Single-nucleotide polymorphisms of matrix metalloproteinases and their inhibitors in gastrointestinal cancer

Figure 1 Schematic overview of the various types of matrix metalloproteinase-producing cells that are involved in the different processes during the various stages of cancer. MMP: Matrix metalloproteinase; TIMP: Tissue inhibitor of metalloproteinase.

Figure 2 Forest plot of gastrointestinal cancer risk associated with the MMP-2 -1306 C/T polymorphism. Results are expressed as Odds ratios ± 95% confidence interval (CI) for CC vs CT+TT. The size of the diamonds indicates the size of the study cohort.