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Case Report
Copyright ©The Author(s) 2026.
World J Gastrointest Oncol. Feb 15, 2026; 18(2): 113494
Published online Feb 15, 2026. doi: 10.4251/wjgo.v18.i2.113494
Figure 1
Figure 1 The endoscopic examination results indicated esophageal neoplastic lesions. A: White-light endoscopy showing significant mucosal stenosis at 30 cm from incisors, with a soft and friable lesion; B: Endoscopic ultrasound demonstrating loss of normal mural layer structure and serosal interruption at lesion site (max wall thickness: 1.11 cm).
Figure 2
Figure 2  Whole-body absorption graph.
Figure 3
Figure 3 Chest computed tomography imaging. A: Showing mid-esophageal wall thickening and subcarinal lymphadenopathy when the patient presented to the thoracic surgeon; B: Showing the volume of the esophageal tumor increased, causing the esophageal lumen to narrow, after two cycles of neoadjuvant immunochemotherapy.
Figure 4
Figure 4 Hematoxylin and eosin stain of tumor biopsy (100 ×). A: Esophageal tumor; B: Primary rectal adenocarcinoma.
Figure 5
Figure 5 Immunohistochemistry results of esophageal tumor. A: CDX-2; B: SATB2.
Figure 6
Figure 6 Immunohistochemistry results of primary rectal adenocarcinoma. A: CDX-2; B: SATB2.
Figure 7
Figure 7  Radiotherapy target graph showing planning target volume.
Figure 8
Figure 8  Chest computed tomography imaging showing a partial response at the three-month follow-up after radiotherapy completion.