SFRP4 expression correlates with epithelial mesenchymal transition-linked genes and poor overall survival in colon cancer patients

Figure 1 SFRP4 co-expresses with epithelial mesenchymal transition-linked genes in colon cancer. SFRP4 and the epithelial mesenchymal transition-linked genes have higher expression in samples that are more mesenchymal (red) compared to the more epithelial samples with lower expression (blue).

Figure 2 Epithelial mesenchymal transition-linked genes with positive correlation with SFRP4 expression.

Figure 3 Epithelial mesenchymal transition-linked genes with negative correlation SFRP4 express.

Figure 4 Overall survival of colon cancer patients with low, intermediate or high SFRP4 expression. A: Patients expressing higher levels of SFRP4 (red line) had poor survival compared to those expressing lower SFRP4 levels (blue line); (B) When a three group analysis was performed, patients with higher SFRP4 expression (red line) presented with poor overall survival compared to patients with intermediate (white lines) or low expression (blue line).