Gut-associated lymphoid tissue or so-called “dome” carcinoma of the colon: Review

Figure 1 Hematoxylin and eosin stains. A: Low power view of a gut- or gastrointestinal-associated lymphoid tissue/dome-type carcinoma showing a well-circumscribed submucosal nodular lesion composed of cystic glands seemingly embedded in a rich lymphoid matrix; B: The cells lining the cystic glands are columnar with eosinophilic, oncocytic cytoplasm displaying minimal cytological atypia and lacking goblet cells; C: The lumina of the cystic glands are distended by non-necrotic eosinophilic material; D: The very prominent lymphoid component is organized into follicles with reactive germinal centers.