This study aims to review deep learning applications for detecting head and neck cancer (HNC) using magnetic resonance imaging (MRI) and radiographic data.

Through January 2023, a PubMed, Scopus, Embase, Google Scholar, IEEE, and arXiv search were carried out. The inclusion criteria were implementing head and neck medical images (computed tomography (CT), positron emission tomography (PET), MRI, Planar scans, and panoramic X-ray) of human subjects with segmentation, object detection, and classification deep learning models for head and neck cancers. The risk of bias was rated with the quality assessment of diagnostic accuracy studies (QUADAS-2) tool. For the meta-analysis diagnostic odds ratio (DOR) was calculated. Deeks' funnel plot was used to assess publication bias. MIDAS and Metandi packages were used to analyze diagnostic test accuracy in STATA.

From 1967 studies, 32 were found eligible after the search and screening procedures. According to the QUADAS-2 tool, 7 included studies had a low risk of bias for all domains. According to the results of all included studies, the accuracy varied from 82.6 to 100%. Additionally, specificity ranged from 66.6 to 90.1%, sensitivity from 74 to 99.68%. Fourteen studies that provided sufficient data were included for meta-analysis. The pooled sensitivity was 90% (95% CI 0.820.94), and the pooled specificity was 92% (CI 95% 0.87-0.96). The DORs were 103 (27-251). Publication bias was not detected based on the p-value of 0.75 in the meta-analysis.

With a head and neck screening deep learning model, detectable screening processes can be enhanced with high specificity and sensitivity.

Distinguishing between primary clear cell carcinoma of the liver (PCCCL) and common hepatocellular carcinoma (CHCC) through traditional inspection methods before the operation is difficult. This study aimed to establish a Faster region-based convolutional neural network (RCNN) model for the accurate differential diagnosis of PCCCL and CHCC.

In this study, we collected the data of 62 patients with PCCCL and 1079 patients with CHCC in Beijing YouAn Hospital from June 2012 to May 2020. A total of 109 patients with CHCC and 42 patients with PCCCL were randomly divided into the training validation set and the test set in a ratio of 4:1.The Faster RCNN was used for deep learning of patients' data in the training validation set, and established a convolutional neural network model to distinguish PCCCL and CHCC. The accuracy, average precision, and the recall of the model for diagnosing PCCCL and CHCC were used to evaluate the detection performance of the Faster RCNN algorithm.

A total of 4392 images of 121 patients (1032 images of 33 patients with PCCCL and 3360 images of 88 patients with CHCC) were uesd in test set for deep learning and establishing the model, and 1072 images of 30 patients (320 images of nine patients with PCCCL and 752 images of 21 patients with CHCC) were used to test the model. The accuracy of the model for accurately diagnosing PCCCL and CHCC was 0.962 (95% confidence interval [CI]: 0.931-0.992). The average precision of the model for diagnosing PCCCL was 0.908 (95% CI: 0.823-0.993) and that for diagnosing CHCC was 0.907 (95% CI: 0.823-0.993). The recall of the model for diagnosing PCCCL was 0.951 (95% CI: 0.916-0.985) and that for diagnosing CHCC was 0.960 (95% CI: 0.854-0.962). The time to make a diagnosis using the model took an average of 4 s for each patient.

The Faster RCNN model can accurately distinguish PCCCL and CHCC. This model could be important for clinicians to make appropriate treatment plans for patients with PCCCL or CHCC.

Esophageal cancer (EC) is a significant global health problem, with an estimated 7th highest incidence and 6th highest mortality rate. Timely diagnosis and treatment are critical for improving patients' outcomes, as over 40% of patients with EC are diagnosed after metastasis. Recent advances in machine learning (ML) techniques, particularly in computer vision, have demonstrated promising applications in medical image processing, assisting clinicians in making more accurate and faster diagnostic decisions. Given the significance of early detection of EC, this systematic review aims to summarize and discuss the current state of research on ML-based methods for the early detection of EC.

We conducted a comprehensive systematic search of five databases (PubMed, Scopus, Web of Science, Wiley, and IEEE) using search terms such as "ML", "Deep Learning (DL (", "Neural Networks (NN)", "Esophagus", "EC" and "Early Detection". After applying inclusion and exclusion criteria, 31 articles were retained for full review.

The results of this review highlight the potential of ML-based methods in the early detection of EC. The average accuracy of the reviewed methods in the analysis of endoscopic and computed tomography (CT (images of the esophagus was over 89%, indicating a high impact on early detection of EC. Additionally, the highest percentage of clinical images used in the early detection of EC with the use of ML was related to white light imaging (WLI) images. Among all ML techniques, methods based on convolutional neural networks (CNN) achieved higher accuracy and sensitivity in the early detection of EC compared to other methods.

Our findings suggest that ML methods may improve accuracy in the early detection of EC, potentially supporting radiologists, endoscopists, and pathologists in diagnosis and treatment planning. However, the current literature is limited, and more studies are needed to investigate the clinical applications of these methods in early detection of EC. Furthermore, many studies suffer from class imbalance and biases, highlighting the need for validation of detection algorithms across organizations in longitudinal studies.

There are few studies on esophageal adenosquamous carcinoma (ADSC). Our study intended to investigate the clinical and survival features of ADSC. We included esophageal cancer (EC) data from the Surveillance, Epidemiology, and End Results program database to explore clinical and survival traits. Propensity score matching (PSM), the multivariate Cox regression model, and survival curves were used in this study. A total of 137 patients with ADSC were included in our analysis. The proportion of ADSC within the EC cohort declined from 2004 to 2018. Besides, results indicated no significant difference in survival between ADSC and SCC groups (PSM-adjusted HR = 1.249, P = 0.127). However, the survival rate of the ADSC group was significantly worse than that of the ADC group (PSM-adjusted HR = 1.497, P = 0.007). For the ADSC group, combined treatment with surgery had a higher survival rate than other treatment methods (all P < 0.001). Surgical resection, radiotherapy, and chemotherapy were independent protective prognostic factors (all P < 0.05). The proportion of ADSC has been declining from 2004 to 2018. The prognosis of ADSC is not significantly different from that of SCC but is worse than that of ADC. Surgery, radiotherapy, and chemotherapy could improve the prognosis of patients. Comprehensive treatment with surgery as the main treatment is more beneficial for some patients.

Esophageal cancer has become one of the important cancers that seriously threaten human life and health, and its incidence and mortality rate are still among the top malignant tumors. Histopathological image analysis is the gold standard for diagnosing different differentiation types of esophageal cancer.

The grading accuracy and interpretability of the auxiliary diagnostic model for esophageal cancer are seriously affected by small interclass differences, imbalanced data distribution, and poor model interpretability. Therefore, we focused on developing the category imbalance attention block network (CIABNet) model to try to solve the previous problems.

First, the quantitative metrics and model visualization results are integrated to transfer knowledge from the source domain images to better identify the regions of interest (ROI) in the target domain of esophageal cancer. Second, in order to pay attention to the subtle interclass differences, we propose the concatenate fusion attention block, which can focus on the contextual local feature relationships and the changes of channel attention weights among different regions simultaneously. Third, we proposed a category imbalance attention module, which treats each esophageal cancer differentiation class fairly based on aggregating different intensity information at multiple scales and explores more representative regional features for each class, which effectively mitigates the negative impact of category imbalance. Finally, we use feature map visualization to focus on interpreting whether the ROIs are the same or similar between the model and pathologists, thus better improving the interpretability of the model.

The experimental results show that the CIABNet model outperforms other state-of-the-art models, which achieves the most advanced results in classifying the differentiation types of esophageal cancer with an average classification accuracy of 92.24%, an average precision of 93.52%, an average recall of 90.31%, an average F1 value of 91.73%, and an average AUC value of 97.43%. In addition, the CIABNet model has essentially similar or identical to the ROI of pathologists in identifying histopathological images of esophageal cancer.

Our experimental results prove that our proposed computer-aided diagnostic algorithm shows great potential in histopathological images of multi-differentiated types of esophageal cancer.

Effective identification of apple leaf diseases can reduce pesticide spraying and improve apple fruit yield, which is significant to agriculture. However, the existing apple leaf disease detection models lack consideration of disease diversity and accuracy, which hinders the application of intelligent agriculture in the apple industry. In this paper, we explore an accurate and robust detection model for apple leaf disease called Apple-Net, improving the conventional YOLOv5 network by adding the Feature Enhancement Module (FEM) and Coordinate Attention (CA) methods. The combination of the feature pyramid and pan in YOLOv5 can obtain richer semantic information and enhance the semantic information of low-level feature maps but lacks the output of multi-scale information. Thus, the FEM was adopted to improve the output of multi-scale information, and the CA was used to improve the detection efficiency. The experimental results show that Apple-Net achieves a higher mAP@0.5 (95.9%) and precision (93.1%) than four classic target detection models, thus proving that Apple-Net achieves more competitive results on apple leaf disease identification.

Esophageal cancer (EC) is a commonly occurring malignant tumor that significantly affects human health. Earlier recognition and classification of EC or premalignant lesions can result in highly effective targeted intervention. Accurate detection and classification of distinct stages of EC provide effective precision therapy planning and improve the 5-year survival rate. Automated recognition of EC can aid physicians in improving diagnostic performance and accuracy. However, the classification of EC is challenging due to identical endoscopic features, like mucosal erosion, hyperemia, and roughness. The recent developments of deep learning (DL) and computer-aided diagnosis (CAD) models have been useful for designing accurate EC classification models. In this aspect, this study develops an atom search optimization with a deep transfer learning-driven EC classification (ASODTL-ECC) model. The presented ASODTL-ECC model mainly examines the medical images for the existence of EC in a timely and accurate manner. To do so, the presented ASODTL-ECC model employs Gaussian filtering (GF) as a preprocessing stage to enhance image quality. In addition, the deep convolution neural network- (DCNN-) based residual network (ResNet) model is applied as a feature extraction approach. Besides, ASO with an extreme learning machine (ELM) model is utilized for identifying the presence of EC, showing the novelty of the work. The performance of the ASODTL-ECC model is assessed and compared with existing models under several medical images. The experimental results pointed out the improved performance of the ASODTL-ECC model over recent approaches.

The objective of this study was to adopt the high-resolution computed tomography (HRCT) technology based on the faster-region recurrent convolutional neural network (Faster-RCNN) algorithm to evaluate the lung infection in patients with type 2 diabetes, so as to analyze the application value of imaging features in the assessment of pulmonary disease in type 2 diabetes. In this study, 176 patients with type 2 diabetes were selected as the research objects, and they were divided into different groups based on gender, course of disease, age, glycosylated hemoglobin level (HbA1c), 2 h C peptide (2 h C-P) after meal, fasting C peptide (FC-P), and complications. The research objects were performed with HRCT scan, and the Faster-RCNN algorithm model was built to obtain the imaging features. The relationships between HRCT imaging features and 2 h C-P, FC-P, HbA1c, gender, course of disease, age, and complications were analyzed comprehensively. The results showed that there were no significant differences in HRCT scores between male and female patients, patients of various ages, and patients with different HbA1c contents (P > 0.05). As the course of disease and complications increased, HRCT scores of patients increased obviously (P < 0.05). The HRCT score decreased dramatically with the increase in the contents of 2 h C-P and FC-P after the meal (P < 0.05). In addition, the results of the Spearman rank correlation analysis showed that the course of disease and complications were positively correlated with the HRCT scores, while the 2 h C-P and FC-P levels after meal were negatively correlated with the HRCT scores. The receiver operating curve (ROC) showed that the accuracy, specificity, and sensitivity of HRCT imaging based on Faster-RCNN algorithm were 90.12%, 90.43%, and 83.64%, respectively, in diagnosing lung infection of patients with type 2 diabetes. In summary, the HRCT imaging features based on the Faster-RCNN algorithm can provide effective reference information for the diagnosis and condition assessment of lung infection in patients with type 2 diabetes.