| For: | Zenonos K, Kyprianou K. RAS signaling pathways, mutations and their role in colorectal cancer. World J Gastrointest Oncol 2013; 5(5): 97-101 [PMID: 23799159 DOI: 10.4251/wjgo.v5.i5.97] |
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| URL: | https://www.wjgnet.com/1948-5204/full/v5/i5/97.htm |
| Number | Citing Articles |
| 1 |
Mohamed Mahmoud, Amr Ahmed WalyEldeen, Mohamed A. Samie, Ahmed M. Sadek, Sayed Elakhras, Mohamed Samir, Osama Ahmed, Rasha Mohamed Samir Sayed, Ahmed Abdelaziz Baiomy, Sherif Abdelaziz Ibrahim, Hebatallah Hassan. Overexpression of miR-21-5p as a potential pathogenesis marker for ovarian endometriosis. The Journal of Basic and Applied Zoology 2025; 86(1) doi: 10.1186/s41936-024-00414-5
|
| 2 |
Frédéric Morinet, Mathilde Parent, Corinne Bergeron, Sylvie Pillet, Claude Capron. Oxygen and viruses: a breathing story. Journal of General Virology 2015; 96(8) doi: 10.1099/vir.0.000172
|
| 3 |
Hamizah Ibrahim, Ya Chee Lim. KRAS-associated microRNAs in colorectal cancer. Oncology Reviews 2020; 14(2) doi: 10.4081/oncol.2020.454
|
| 4 |
Jamal Zekri, Mohammed A. Baghdadi, Hosam Alardati, Hamoud Khallaf, Juma H. Kabanja. Evaluation of the Idylla KRAS and NRAS mutation test in colorectal cancer tissue. Experimental and Molecular Pathology 2019; 110 doi: 10.1016/j.yexmp.2019.104270
|
| 5 |
Stéphane Rossat, Hervé Perrier, Marine Lefevre, Christophe Louvet, Nathalie Le Berre, Jérôme Chamois, Maryline Dorel, Daniel Vacque, Angélique Guillaudeau, Dominique Genet, Evelyne Maillet, Simon Triby, Jean-Christophe Sabourin. Drastic Reduction of Turnaround Time After Implementation of a Fully Automated Assay for RAS-BRAF Mutations in Colorectal Cancer: A Pilot Prospective Study in Real-life Conditions. Pathology & Oncology Research 2020; 26(4) doi: 10.1007/s12253-020-00818-y
|
| 6 |
Neha Zutshi, Bhopal C. Mohapatra, Pinaki Mondal, Wei An, Benjamin T. Goetz, Shuo Wang, Sicong Li, Matthew D. Storck, David F. Mercer, Adrian R. Black, Sarah P. Thayer, Jennifer D. Black, Chi Lin, Vimla Band, Hamid Band. Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance. iScience 2024; 27(6) doi: 10.1016/j.isci.2024.109912
|
| 7 |
Iemmolo Rosario, Guarnaccia Maria, Petralia Salvatore, Cavallaro Sebastiano, Conoci Sabrina. Sensors. Lecture Notes in Electrical Engineering 2019; 539 doi: 10.1007/978-3-030-04324-7_53
|
| 8 |
Ege Ulgen, Ozan Ozisik, Osman Ugur Sezerman. pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks. Frontiers in Genetics 2019; 10 doi: 10.3389/fgene.2019.00858
|
| 9 |
Yang Ni, Yuan Ji, Peter Müller. Reciprocal Graphical Models for Integrative Gene Regulatory Network Analysis. Bayesian Analysis 2018; 13(4) doi: 10.1214/17-BA1087
|
| 10 |
Tikam Chand Dakal, Ramgopal Dhakar, Abhijit Beura, Kareena Moar, Pawan Kumar Maurya, Narendra Kumar Sharma, Vipin Ranga, Abhishek Kumar. Emerging methods and techniques for cancer biomarker discovery. Pathology - Research and Practice 2024; 262 doi: 10.1016/j.prp.2024.155567
|
| 11 |
Emilia Díaz, Anthony Febres, Michelle Giammarresi, Adrian Silva, Oriana Vanegas, Carlos Gomes, Alicia Ponte-Sucre. G Protein-Coupled Receptors as Potential Intercellular Communication Mediators in Trypanosomatidae. Frontiers in Cellular and Infection Microbiology 2022; 12 doi: 10.3389/fcimb.2022.812848
|
| 12 |
Amy Rios, Kimberly A. Jorge, Gizelle G. Ramirez, Chester A. Thompson, Tikvah K. Hayes. Impact of lineage-specific epidermal growth factor receptor mutations in cancer. Philosophical Transactions of the Royal Society B: Biological Sciences 2026; 381(1957) doi: 10.1098/rstb.2024.0501
|
| 13 |
Phoenix D Bell, Reetesh K Pai. Immune response in colorectal carcinoma: a review of its significance as a predictive and prognostic biomarker. Histopathology 2022; 81(6) doi: 10.1111/his.14713
|
| 14 |
Arathi Nair, Prashant Chauhan, Bhaskar Saha, Katharina F. Kubatzky. Conceptual Evolution of Cell Signaling. International Journal of Molecular Sciences 2019; 20(13) doi: 10.3390/ijms20133292
|
| 15 |
Ajaratu Keshinro, Chad Vanderbilt, Jin K. Kim, Canan Firat, Chin-Tung Chen, Rona Yaeger, Karuna Ganesh, Neil H. Segal, Mithat Gonen, Jinru Shia, Zsofia Stadler, Martin R. Weiser. Tumor-Infiltrating Lymphocytes, Tumor Mutational Burden, and Genetic Alterations in Microsatellite Unstable, Microsatellite Stable, or Mutant POLE/POLD1 Colon Cancer. JCO Precision Oncology 2021; (5) doi: 10.1200/PO.20.00456
|
| 16 |
Jiyauddin Khan, Priyanjana Ghosh, Urmi Bajpai, Kountay Dwivedi, Daman Saluja. Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for therapeutic potential. Discover Oncology 2024; 15(1) doi: 10.1007/s12672-024-01712-8
|
| 17 |
Cheng Xu, Yulin Chen, Feiwu Long, Junman Ye, Xue Li, Qiaorong Huang, Dejiao Yao, Xiaoli Wang, Jin Zhao, Wentong Meng, Xianming Mo, Ran Lu, Chuanwen Fan, Tao Zhang. Prognostic value and biological function of LRRN4 in colorectal cancer. Cancer Cell International 2022; 22(1) doi: 10.1186/s12935-022-02579-x
|
| 18 |
Benjamin D. Young, Dana E. Williams, Allan J. Bright, Annie Peterson, Nikki Traylor-Knowles, Stephane M. Rosales. Genet identity and season drive gene expression in outplanted Acropora palmata at different reef sites. Scientific Reports 2024; 14(1) doi: 10.1038/s41598-024-80479-y
|
| 19 |
Matin Shaikh, Yashodeep Shinde, Rahul Pawara, Malleshappa Noolvi, Sanjay Surana, Iqrar Ahmad, Harun Patel. Emerging Approaches to Overcome Acquired Drug Resistance Obstacles to Osimertinib in Non-Small-Cell Lung Cancer. Journal of Medicinal Chemistry 2022; 65(2) doi: 10.1021/acs.jmedchem.1c00876
|
| 20 |
Ramya Ephraim, Sarah Fraser, Jeannie Devereaux, Rhian Stavely, Jack Feehan, Rajaraman Eri, Kulmira Nurgali, Vasso Apostolopoulos. Differential Gene Expression of Checkpoint Markers and Cancer Markers in Mouse Models of Spontaneous Chronic Colitis. Cancers 2023; 15(19) doi: 10.3390/cancers15194793
|
| 21 |
Yuwares Malila, Tanaporn Uengwetwanit, Sopacha Arayamethakorn, Yanee Srimarut, Krittaporn V. Thanatsang, Francesca Soglia, Gale M. Strasburg, Wanilada Rungrassamee, Wonnop Visessanguan. Transcriptional Profiles of Skeletal Muscle Associated With Increasing Severity of White Striping in Commercial Broilers. Frontiers in Physiology 2020; 11 doi: 10.3389/fphys.2020.00580
|
| 22 |
Lokesh Kumar Bhatt, Niraj Parihar, Kedar S. Prabhavalkar. The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases. Advances in Biochemistry in Health and Disease 2023; 25 doi: 10.1007/978-3-031-23621-1_22
|
| 23 |
Nourhan Abu-Shahba, Elsayed Hegazy, Faiz M. Khan, Mahmoud Elhefnawi. In Silico Analysis of MicroRNA Expression Data in Liver Cancer. Cancer Informatics 2023; 22 doi: 10.1177/11769351231171743
|
| 24 |
Ritwik Patra, Amit Kumar Dey, Suprabhat Mukherjee, Divijendra Natha Reddy Sirigiri. Identification of genes critical for inducing ulcerative colitis and exploring their tumorigenic potential in human colorectal carcinoma. PLOS ONE 2023; 18(8) doi: 10.1371/journal.pone.0289064
|
| 25 |
Sandeep Palvai, Meenu Mahesh Kuman, Sudipta Basu. Hyaluronic acid cloaked oleic acid nanoparticles inhibit MAPK signaling with sub-cellular DNA damage in colon cancer cells. Journal of Materials Chemistry B 2017; 5(20) doi: 10.1039/C7TB00656J
|
| 26 |
Yasin Ahmadi, Javad Khalili Fard, Dlzar Ghafoor, Ali H. Eid, Amirhossein Sahebkar. Paradoxical effects of statins on endothelial and cancer cells: the impact of concentrations. Cancer Cell International 2023; 23(1) doi: 10.1186/s12935-023-02890-1
|
| 27 |
Aoife Carr, Jonathan A. Coulter, Julie Workman, Joanna Fay, Angela Farrelly, Alex J. Eustace, Lindsey Bennie, Liam Grogan, Oscar Breathnach, Patrick G. Morris, Deborah A. McNamara, Mattia Cremona, Brian D.P. O'Neill, Bryan T. Hennessy, Sinead Toomey. Targeting the phosphatidylinositol-3-kinase (PI3K) and mitogen activated protein kinase (MAPK) signalling pathways to enhance chemoradiotherapy in locally advanced rectal cancer. Cancer Treatment and Research Communications 2025; 43 doi: 10.1016/j.ctarc.2025.100926
|
| 28 |
Catharina Olsen, Kathleen Fleming, Niall Prendergast, Renee Rubio, Frank Emmert-Streib, Gianluca Bontempi, John Quackenbush, Benjamin Haibe-Kains. Using shRNA experiments to validate gene regulatory networks. Genomics Data 2015; 4 doi: 10.1016/j.gdata.2015.03.011
|
| 29 |
Jeng-Wei Lu, Yuxi Sun, Pei-Shi Angelina Fong, Liang-In Lin, Dong Liu, Zhiyuan Gong. Lipopolysaccharides Enhance Epithelial Hyperplasia and Tubular Adenoma in Intestine-Specific Expression of krasV12 in Transgenic Zebrafish. Biomedicines 2021; 9(8) doi: 10.3390/biomedicines9080974
|
| 30 |
Yvonne Saara Gladbach, Leonie Wiegele, Mohamed Hamed, Anna-Marie Merkenschläger, Georg Fuellen, Christian Junghanss, Claudia Maletzki. Unraveling the Heterogeneous Mutational Signature of Spontaneously Developing Tumors in MLH1−/− Mice. Cancers 2019; 11(10) doi: 10.3390/cancers11101485
|
| 31 |
Tabata Barbosa-Rojas, Ilya Ioshikhes, Raghvendra All. Placental microRNAs as potential regulators in tumour processes. ScienceBank 2026; doi: 10.61340/PLACMIRNAS
|
| 32 |
Hooi Xian Lee, Wai Ming Li, Chee Wei Ang, Kerry Reimer, Victor Liu, Brian O. Patrick, Keng Yoon Yeong, Chow H. Lee. Regio- and stereoselective synthesis of dispiropyrrolizidines through 1,3-dipolar cycloaddition reaction: Inhibition of KRAS expression. Journal of Molecular Structure 2022; 1263 doi: 10.1016/j.molstruc.2022.133177
|
| 33 |
Maryam Alizadeh-Sedigh, Habibollah Mahmoodzadeh, Mohammad Sadegh Fazeli, Mohammad Haddadi-Aghdam, Ladan Teimoori-Toolabi. The potential of PIK3CA, KRAS, BRAF, and APC hotspot mutations as a non-invasive detection method for colorectal cancer. Molecular and Cellular Probes 2022; 63 doi: 10.1016/j.mcp.2022.101807
|
| 34 |
Nima Mohseni, Majid Ghaniee Zarich, Saeid Afshar, Manouchehr Hosseini. Identification of Novel Biomarkers for Response to Preoperative Chemoradiation in Locally Advanced Rectal Cancer with Genetic Algorithm–Based Gene Selection. Journal of Gastrointestinal Cancer 2023; 54(3) doi: 10.1007/s12029-022-00873-5
|
| 35 |
Louise Johnston, Michael Power, Philip Sloan, Anna Long, Angela Silmon, Ben Chaffey, Andrea Jane Lisgo, Liam Little, Ellen Vercauteren, Torben Steiniche, Tine Meyer, John Simpson. Clinical performance evaluation of the Idylla NRAS-BRAF mutation test on retrospectively collected formalin-fixed paraffin-embedded colorectal cancer tissue. Journal of Clinical Pathology 2018; 71(4) doi: 10.1136/jclinpath-2017-204629
|
| 36 |
Weinan Xue, Xiangxin Wu, Fan Wang, Peng Han, Binbin Cui. Genome-wide methylation analysis identifies novel prognostic methylation markers in colon adenocarcinoma. Biomedicine & Pharmacotherapy 2018; 108 doi: 10.1016/j.biopha.2018.09.043
|
| 37 |
Maryam Hassanlou, Bahram M. Soltani, Abdallah Medlej, Maryam Kay, Seyed Javad Mowla. Hsa-miR-6165 downregulates insulin-like growth factor-1 receptor (IGF-1R) expression and enhances apoptosis in SW480 cells. Biological Chemistry 2020; 401(4) doi: 10.1515/hsz-2018-0421
|
| 38 |
Ozkan Kanat, Hulya Ertas, Burcu Caner. Dual HER2 inhibition strategies in the management of treatment-refractory metastatic colorectal cancer: History and status. World Journal of Clinical Cases 2018; 6(11): 418-425 doi: 10.12998/wjcc.v6.i11.418
|
| 39 |
Tim Svenstrup Poulsen, Douglas Vinicius Nogueira Perez de Oliveira, Maiken Lise Marcker Espersen, Louise Laurberg Klarskov, Wojciech Skovrider‐Ruminski, Estrid Hogdall. Frequency and coexistence of KRAS, NRAS, BRAF and PIK3CA mutations and occurrence of MMR deficiency in Danish colorectal cancer patients. APMIS 2021; 129(2) doi: 10.1111/apm.13091
|
| 40 |
Xinyu Ma, Zhibo Zhou, Shuyu Gu, Yan Guo, Tianqing Zhou, Ruonan Shao, Jinsong Yan, Wei Chen, Xiaofeng Shi. Advances in the Diagnosis and Treatment of Myeloproliferative Neoplasms (MPNs). Cancers 2025; 17(19) doi: 10.3390/cancers17193142
|
| 41 |
Sergey G. Klochkov, Margarita E. Neganova, Nagendra Sastry Yarla, Madhukiran Parvathaneni, Bechan Sharma, Vadim V. Tarasov, George Barreto, Sergey O. Bachurin, Ghulam Md Ashraf, Gjumrakch Aliev. Implications of farnesyltransferase and its inhibitors as a promising strategy for cancer therapy. Seminars in Cancer Biology 2019; 56 doi: 10.1016/j.semcancer.2017.10.010
|
| 42 |
Mohammad Mehdi Gravandi, Sadaf Abdian, Maedeh Tahvilian, Amin Iranpanah, Seyed Zachariah Moradi, Sajad Fakhri, Javier Echeverría. Therapeutic targeting of Ras/Raf/MAPK pathway by natural products: A systematic and mechanistic approach for neurodegeneration. Phytomedicine 2023; 115 doi: 10.1016/j.phymed.2023.154821
|
| 43 |
Yusuke Makutani, Kazuko Sakai, Masahiro Yamada, Toshiaki Wada, Takaaki Chikugo, Takao Satou, Yoko Iwasa, Hidekazu Yamamoto, Marco A. de Velasco, Kazuto Nishio, Junichiro Kawamura. Performance of Idylla™ RAS-BRAF mutation test for formalin-fixed paraffin-embedded tissues of colorectal cancer. International Journal of Clinical Oncology 2022; 27(7) doi: 10.1007/s10147-022-02167-z
|
| 44 |
Magdalena Dabrowska, Marek Skoneczny, Lukasz Uram, Wojciech Rode. Methotrexate-induced senescence of human colon cancer cells depends on p53 acetylation, but not genomic aberrations. Anti-Cancer Drugs 2019; 30(4) doi: 10.1097/CAD.0000000000000731
|
| 45 |
Fuyan Hu, Wenying Zeng, Xiaoping Liu. A Gene Signature of Survival Prediction for Kidney Renal Cell Carcinoma by Multi-Omic Data Analysis. International Journal of Molecular Sciences 2019; 20(22) doi: 10.3390/ijms20225720
|
| 46 |
Yu-Tang Chang, Chou-Chen Chen, Shih-Ching Chang, Yu-Yao Chang, Bo-Wen Lin, Hong-Hwa Chen, Yao-Yu Hsieh, Hung-Chih Hsu, Meng-Che Hsieh, Feng-Che Kuan, Chih-Chien Wu, Wei-Chen Lu, Yu-Li Su, Yi-Hsin Liang, Joe-Bin Chen, Shuan-Yuan Huang, Ching-Wen Huang, Jaw-Yuan Wang. Efficacy and Safety of a Parenteral Nutrition Program for Patients with RAS Wild-Type Metastatic Colorectal Cancer Administered First-Line Cetuximab Plus Chemotherapy: A Propensity Score Matching Study. Nutrients 2023; 15(13) doi: 10.3390/nu15132971
|
| 47 |
Khalid Jazieh, Julian Molina, Jacob Allred, Jun Yin, Joel Reid, Matthew Goetz, Vun-Sin Lim, Scott H. Kaufmann, Alex Adjei. A phase I study of the farnesyltransferase inhibitor Tipifarnib in combination with the epidermal growth factor tyrosine kinase inhibitor Erlotinib in patients with advanced solid tumors. Investigational New Drugs 2019; 37(2) doi: 10.1007/s10637-018-0662-1
|
| 48 |
Yan Shen, Bin Lu, Shuo Zhang, Zhong-Jun Ma. Diterpenoid C of Radix Curcumae: An inhibitor of proliferation and inducer of apoptosis in human colon adenocarcinoma cells acting via inhibiting MAPK signaling pathway. Pharmaceutical Biology 2014; 52(9) doi: 10.3109/13880209.2013.879907
|
| 49 |
Doulathunnisa Jaffar Ali, Cong He, Huantian Xu, Subhashree Kumaravel, Bo Sun, Yunting Zhou, Rui Liu, Zhongdang Xiao. Microvesicles mediate sorafenib resistance in liver cancer cells through attenuating p53 and enhancing FOXM1 expression. Life Sciences 2021; 271 doi: 10.1016/j.lfs.2021.119149
|
| 50 |
Agata N. Burska, Bayansulu Ilyassova, Aruzhan Dildabek, Medina Khamijan, Dinara Begimbetova, Ferdinand Molnár, Dos D. Sarbassov. Enhancing an Oxidative “Trojan Horse” Action of Vitamin C with Arsenic Trioxide for Effective Suppression of KRAS-Mutant Cancers: A Promising Path at the Bedside. Cells 2022; 11(21) doi: 10.3390/cells11213454
|
| 51 |
Qingfeng Huang, Yang Zhou, Bowen Wang, Yi Zhao, Fengxia Zhang, Bowen Ding. Mutational landscape of pan-cancer patients with PIK3CA alterations in Chinese population. BMC Medical Genomics 2022; 15(1) doi: 10.1186/s12920-022-01297-7
|
| 52 |
Eliza Vakana, Susan Pratt, Wayne Blosser, Michele Dowless, Nicholas Simpson, Xiu-Juan Yuan, Susan Jaken, Jason Manro, Jennifer Stephens, Youyan Zhang, Lysiane Huber, Sheng-Bin Peng, Louis F. Stancato. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. Oncotarget 2017; 8(6) doi: 10.18632/oncotarget.14002
|
| 53 |
Fei Teng, Qingqin Gao, Li Zhou, Tongtong Cui, Xiangtian Tan, Yali Ding, Rongqi Li, Bojin Li, Bei Zhong, Miao Miao, Qi Zhou, Wei Li. Targeting RAS-mutant cancer cells using a synthetic RAS-activated cancer killing system. Trends in Biotechnology 2025; 43(12) doi: 10.1016/j.tibtech.2025.07.031
|
| 54 |
Jennifer J. Lee, Vaibhav Jain, Ravi K. Amaravadi. Clinical Translation of Combined MAPK and Autophagy Inhibition in RAS Mutant Cancer. International Journal of Molecular Sciences 2021; 22(22) doi: 10.3390/ijms222212402
|
| 55 |
Jace Chen, Apple Verdiell, Carlos Formoso, Myles Luciano, Celine Chen, Abhimanyu Thakur. Tumor-derived extracellular vesicles: Bridging communication and next-generation theranostics. Biomedicine & Pharmacotherapy 2025; 193 doi: 10.1016/j.biopha.2025.118815
|
| 56 |
Ritwik Patra, Nabarun Chandra Das, Suprabhat Mukherjee. Exploring the Differential Expression and Prognostic Significance of the COL11A1 Gene in Human Colorectal Carcinoma: An Integrated Bioinformatics Approach. Frontiers in Genetics 2021; 12 doi: 10.3389/fgene.2021.608313
|
| 57 |
Ida Christine Jacobsen, Iben Spanggaard, Martin Højgaard, Laïla Belcaid, Camilla Qvortrup, Christina Westmose Yde, Ane Yde Schmidt, Finn Cilius Nielsen, Gro Linno Willemoe, Mikkel Seidelin Dam, Ulrik Lassen, Kristoffer Staal Rohrberg. Extensive genomic analysis in patients with KRAS-mutated solid tumors shows high frequencies of concurrent alterations and potential targets but has limited clinical impact. Acta Oncologica 2022; 61(12) doi: 10.1080/0284186X.2022.2156809
|
| 58 |
Tahani Bakhsh, Safiah Alhazmi, Ali Farsi, Abdulaziz S. Yusuf, Amani Alharthi, Safa H. Qahl, Maha Ali Alghamdi, Faisal A. Alzahrani, Ola H. Elgaddar, Mohanad A. Ibrahim, Ahmed Bahieldin. Molecular detection of exosomal miRNAs of blood serum for prognosis of colorectal cancer. Scientific Reports 2024; 14(1) doi: 10.1038/s41598-024-58536-3
|
| 59 |
Osman Sütcüoğlu, Hasan Çağrı Yıldırım, Elvina Almuradova, Damla Günenç, Şuayib Yalçın. RAS Mutations in Advanced Colorectal Cancer: Mechanisms, Clinical Implications, and Novel Therapeutic Approaches. Medicina 2025; 61(7) doi: 10.3390/medicina61071202
|
| 60 |
Pougang Golmei, Shriyansh Srivastava, Laxmi Yadav, Sachin Kumar. Biosensors and Aptamers. 2025; doi: 10.1007/978-981-96-8387-1_4
|
| 61 |
Lixin Dong, Li Ma, Gloria H. Ma, Hongmei Ren. Genome-wide Analysis Reveals DNA Methylation Alterations in Obesity Associated with High Risk of Colorectal Cancer. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-41616-0
|
| 62 |
Binod Pokhrel, Zhendong Tan, Honglin Jiang. Identification of transcriptional regulators and signaling pathways mediating postnatal rumen growth and functional maturation in cattle. Journal of Animal Science 2025; 103 doi: 10.1093/jas/skae367
|
| 63 |
Anna A. Marusiak, Natalie L. Stephenson, Hayeon Baik, Eleanor W. Trotter, Yaoyong Li, Karen Blyth, Susan Mason, Phil Chapman, Lorena A. Puto, Jon A. Read, Claire Brassington, Hannah K. Pollard, Chris Phillips, Isabelle Green, Ross Overman, Matthew Collier, Ewelina Testoni, Crispin J. Miller, Tony Hunter, Owen J. Sansom, John Brognard. Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis. Cancer Research 2016; 76(3) doi: 10.1158/0008-5472.CAN-15-0701-T
|
| 64 |
Sonia M. Novo, Stephen R. Wedge, Lesley A. Stark. Ex vivo treatment of patient biopsies as a novel method to assess colorectal tumour response to the MEK1/2 inhibitor, Selumetinib. Scientific Reports 2017; 7(1) doi: 10.1038/s41598-017-12222-9
|
| 65 |
Tanos C. C. França, Michael Maddalena, Imène Kouidmi, Yann Ayotte, Salim T. Islam, Steven R. LaPlante. SI/II Pocket of Ras: An Opportunity for a Once “Undruggable” Target. ACS Omega 2025; 10(9) doi: 10.1021/acsomega.4c10493
|
| 66 |
. 2018; doi: 10.70675/eb51eb1ezc51dz4737zaf38z954d1a68dbea
|
| 67 |
Sreyashi Das, Mohan Kumar Dey, Ram Devireddy, Manas Ranjan Gartia. Biomarkers in Cancer Detection, Diagnosis, and Prognosis. Sensors 2023; 24(1) doi: 10.3390/s24010037
|
| 68 |
Chaimaa Mounjid, Hajar El Agouri, Youssef Mahdi, Abdelilah Laraqui, En-nacer Chtati, Soumaya Ech-charif, Mouna Khmou, Youssef Bakri, Amine Souadka, Basma El Khannoussi. Assessment of KRAS and NRAS status in metastatic colorectal cancer: Experience of the National Institute of Oncology in Rabat Morocco. Annals of Cancer Research and Therapy 2022; 30(2) doi: 10.4993/acrt.30.80
|
| 69 |
Setareh Rezatabar, Ansar Karimian, Vahid Rameshknia, Hadi Parsian, Maryam Majidinia, Tayebeh Azramezani Kopi, Anupam Bishayee, Ali Sadeghinia, Mehdi Yousefi, Mohsen Monirialamdari, Bahman Yousefi. RAS/MAPK signaling functions in oxidative stress, DNA damage response and cancer progression. Journal of Cellular Physiology 2019; 234(9) doi: 10.1002/jcp.28334
|
| 70 |
. 2021; doi: 10.70675/75af9f5az2515z4a05z81f7z3294310d6a2d
|
| 71 |
Lisha Wu, Maosheng Xu, Xueqin Li, Dilinuer Aierken, Jinxiu Yu, Tao Qin. A real-world pharmacovigilance study of KRAS G12C mutation inhibitors based on the food and drug administration adverse event reporting system. Frontiers in Pharmacology 2024; 15 doi: 10.3389/fphar.2024.1418469
|
| 72 |
Ashley N. Sigafoos, Brooke D. Paradise, Martin E. Fernandez-Zapico. Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease. Cancers 2021; 13(14) doi: 10.3390/cancers13143410
|
| 73 |
Aditya Lahiri, Haswanth Vundavilli, Madhurima Mondal, Pranabesh Bhattacharjee, Brian Decker, Giuseppe Del Priore, N. Peter Reeves, Aniruddha Datta. Drug Target Identification in Triple Negative Breast Cancer Stem Cell Pathways: A Computational Study of Gene Regulatory Pathways Using Boolean Networks. IEEE Access 2023; 11 doi: 10.1109/ACCESS.2023.3283291
|
| 74 |
Sudip Kumar Ghosh, Raima Das Kundu, Sankar Kumar Ghosh. Whole exome sequencing based coding variation in nasopharyngeal cancer from tribal population of North-East India. Gene Reports 2025; 38 doi: 10.1016/j.genrep.2024.102126
|
| 75 |
Nastaran Masoudi-Khoram, Sara Cheraghi, Mahboobeh Nazari, Mohammad E. Khamseh. Targeting endothelial growth factor receptor in thyroid cancer: current concepts and future directions. Medical Oncology 2025; 42(7) doi: 10.1007/s12032-025-02788-0
|
| 76 |
Maria Guarnaccia, Rosario Iemmolo, Salvatore Petralia, Sabrina Conoci, Sebastiano Cavallaro. Miniaturized Real-Time PCR on a Q3 System for Rapid KRAS Genotyping. Sensors 2017; 17(4) doi: 10.3390/s17040831
|
| 77 |
Vicente Morales-Oyarvide, Chen Yuan, Ana Babic, Sui Zhang, Donna Niedzwiecki, Jennie C Brand-Miller, Laura Sampson-Kent, Xing Ye, Yanping Li, Leonard B Saltz, Robert J Mayer, Rex B Mowat, Renaud Whittom, Alexander Hantel, Al Benson, Daniel Atienza, Michael Messino, Hedy Kindler, Alan Venook, Shuji Ogino, Kana Wu, Walter C Willett, Edward L Giovannucci, Brian M Wolpin, Jeffrey A Meyerhardt, Charles S Fuchs, Kimmie Ng. Dietary Insulin Load and Cancer Recurrence and Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803 (Alliance). JNCI: Journal of the National Cancer Institute 2019; 111(2) doi: 10.1093/jnci/djy098
|
| 78 |
Mohd Asad Farooqi, Kantrol Kumar Sahu. Signaling pathways and molecular mechanisms of lupeol in colorectal cancer: A comprehensive review. Journal of Ayurveda and Integrative Medicine 2026; 17(1) doi: 10.1016/j.jaim.2025.101270
|
| 79 |
. 2020; doi: 10.70675/6265256cz226fz425dza7cdz3f0c5f6590d4
|
| 80 |
Xinying Hu, Hang Wei, Haoran Zheng. Identification of perturbed signaling pathways from gene expression data using information divergence. Molecular BioSystems 2017; 13(9) doi: 10.1039/C7MB00285H
|
| 81 |
Yong-Hee Cho, Eun Ji Ro, Jeong-Su Yoon, Dong-Kyu Kwak, Jaebeom Cho, Dong Woo Kang, Ho-Young Lee, Kang-Yell Choi. Small molecule-induced simultaneous destabilization of β-catenin and RAS is an effective molecular strategy to suppress stemness of colorectal cancer cells. Cell Communication and Signaling 2020; 18(1) doi: 10.1186/s12964-020-0519-z
|
| 82 |
Arash Mohammadinejad, Taraneh Mohajeri, Ghazaleh Aleyaghoob, Fatemeh Heidarian, Reza Kazemi Oskuee. Ellagic acid as a potent anticancer drug: A comprehensive review on in vitro, in vivo, in silico, and drug delivery studies. Biotechnology and Applied Biochemistry 2022; 69(6) doi: 10.1002/bab.2288
|
| 83 |
Makoto Shimozawa, Sakiho Anzai, Reiko Satow, Kiyoko Fukami. Phospholipase C δ1 negatively regulates autophagy in colorectal cancer cells. Biochemical and Biophysical Research Communications 2017; 488(4) doi: 10.1016/j.bbrc.2017.05.098
|
| 84 |
Mahmoud A. Elrebehy, Sarah Al-Saeed, Sara Gamal, Asmaa El-Sayed, Alshaimaa A. Ahmed, Omnia Waheed, Ahmed Ismail, Hesham A. El-Mahdy, Al-Aliaa M. Sallam, Ahmed S. Doghish. miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: A spotlight on signaling pathways interplay — A review. International Journal of Biological Macromolecules 2022; 214 doi: 10.1016/j.ijbiomac.2022.06.134
|
| 85 |
Hani Lee, Nayoung Kim, Young Ji Yoo, Hyejin Kim, Euna Jeong, SeokGyeong Choi, Sung Un Moon, Seung Hyun Oh, Gordon B. Mills, Sukjoon Yoon, Woo-Young Kim. β-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer. Oncogene 2018; 37(40) doi: 10.1038/s41388-018-0362-5
|
| 86 |
Maider Varela-Guruceaga, Sonia Tejada-Solís, Marc García-Moure, Juan Fueyo, Candelaria Gomez-Manzano, Ana Patiño-García, Marta Alonso. Oncolytic Viruses as Therapeutic Tools for Pediatric Brain Tumors. Cancers 2018; 10(7) doi: 10.3390/cancers10070226
|
| 87 |
Suvasmita Rath, Venkateswarlu Perikala, Atala Bihari Jena, Jagneshwar Dandapat. Factors regulating dynamics of angiotensin-converting enzyme-2 (ACE2), the gateway of SARS-CoV-2: Epigenetic modifications and therapeutic interventions by epidrugs. Biomedicine & Pharmacotherapy 2021; 143 doi: 10.1016/j.biopha.2021.112095
|
| 88 |
Cristina Barbagallo, Duilia Brex, Angela Caponnetto, Matilde Cirnigliaro, Marina Scalia, Antonio Magnano, Rosario Caltabiano, Davide Barbagallo, Antonio Biondi, Alessandro Cappellani, Francesco Basile, Cinzia Di Pietro, Michele Purrello, Marco Ragusa. LncRNA UCA1, Upregulated in CRC Biopsies and Downregulated in Serum Exosomes, Controls mRNA Expression by RNA-RNA Interactions. Molecular Therapy Nucleic Acids 2018; 12 doi: 10.1016/j.omtn.2018.05.009
|
| 89 |
Brooke V. Hisrich, R. Brant Young, Alison M. Sansone, Zachary Bowens, Lisa J. Green, Bruce A. Lessey, Anna V. Blenda. Role of Human Galectins in Inflammation and Cancers Associated with Endometriosis. Biomolecules 2020; 10(2) doi: 10.3390/biom10020230
|
| 90 |
Massimiliano Bissa, Veronica Galli, Luca Schifanella, Monica Vaccari, Mohammad Arif Rahman, Giacomo Gorini, Nicolò Binello, Sarkis Sarkis, Anna Gutowska, Isabela Silva de Castro, Melvin N. Doster, Ramona Moles, Guido Ferrari, Xiaoying Shen, Georgia D. Tomaras, David C. Montefiori, Kombo F. N’guessan, Dominic Paquin-Proulx, Pamela A. Kozlowski, David J. Venzon, Hyoyoung Choo-Wosoba, Matthew W. Breed, Joshua Kramer, Genoveffa Franchini. In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4+ T-Cells. Vaccines 2023; 11(11) doi: 10.3390/vaccines11111662
|
| 91 |
Mei Chan, Meghna Shelke, Amanda Townsend, Amitesh Roy, Vy Broadbridge, Christos Karapetis, Timothy Price. From undruggable to actionable: advances in KRAS targeting in colorectal cancer. Academia Oncology 2026; 3(1) doi: 10.20935/AcadOnco8216
|
| 92 |
Jean-Michel Amici, Delphine Kerob, Thierry Passeron, Susana Puig. Photoprotection and the Science Behind Skin Healing. EMJ Dermatology 2022; doi: 10.33590/emjdermatol/10058317
|
| 93 |
Jeng-Wei Lu, Divya Raghuram, Pei-Shi Angelina Fong, Zhiyuan Gong. Inducible Intestine-Specific Expression of kras Triggers Intestinal Tumorigenesis In Transgenic Zebrafish. Neoplasia 2018; 20(12) doi: 10.1016/j.neo.2018.10.002
|
| 94 |
Anurag Mathur, Abha Meena, Suaib Luqman. Monoterpenoids: An upcoming class of therapeutic agents for modulating cancer metastasis. Phytotherapy Research 2024; 38(2) doi: 10.1002/ptr.8081
|
| 95 |
Ya‐Sian Chang, Chien‐Chin Lee, Tao‐Wei Ke, Chieh‐Min Chang, Dy‐San Chao, Hsi‐Yuan Huang, Jan‐Gowth Chang. Molecular characterization of colorectal cancer using whole‐exome sequencing in a Taiwanese population. Cancer Medicine 2019; 8(8) doi: 10.1002/cam4.2282
|
| 96 |
Lei Yang, Nigora Atakhanova, Meryelem Tania Churampi Arellano, Mohammed Yassen Mohamed, Thamer Hani, Ali A. Fahdil, Roxana Yolanda Castillo-Acobo, Ashima Juyal, Ahlam Kadhim Hussein, Ali H. Amin, Renzon Daniel Cosme Pecho, Reza Akhavan-Sigari. Translational research of new developments in targeted therapy of colorectal cancer. Pathology - Research and Practice 2023; 252 doi: 10.1016/j.prp.2023.154888
|
| 97 |
Sanket Bapat, Saim Momin, Renu Vyas. Advances in Bioengineering. 2020; doi: 10.1007/978-981-15-2063-1_1
|
| 98 |
Ana Calheiros de Carvalho, Claudio Yoshio Ogawa, Luiza De Camillis Rodrigues, Lívia Soman de Medeiros, Thiago André Moura Veiga. Penicillium genus as a source for anti-leukemia compounds: an overview from 1984 to 2020. Leukemia & Lymphoma 2021; 62(9) doi: 10.1080/10428194.2021.1897804
|
| 99 |
Shaheedul A. Sami, Noureldien H. E. Darwish, Amanda N. M. Barile, Shaker A. Mousa. Current and Future Molecular Targets for Acute Myeloid Leukemia Therapy. Current Treatment Options in Oncology 2020; 21(1) doi: 10.1007/s11864-019-0694-6
|
| 100 |
Sajal Raj Singh, Rakesh Bhaskar, Shampa Ghosh, Bhuvaneshwar Yarlagadda, Krishna Kumar Singh, Prashant Verma, Sonali Sengupta, Mitko Mladenov, Nikola Hadzi-Petrushev, Radoslav Stojchevski, Jitendra Kumar Sinha, Dimiter Avtanski. Exploring the Genetic Orchestra of Cancer: The Interplay Between Oncogenes and Tumor-Suppressor Genes. Cancers 2025; 17(7) doi: 10.3390/cancers17071082
|
| 101 |
Md. Arafat Hossain. Targeting the RAS upstream and downstream signaling pathway for cancer treatment. European Journal of Pharmacology 2024; 979 doi: 10.1016/j.ejphar.2024.176727
|
| 102 |
Parinaz Motiei, Hamid Reza Heidari, Mohammad Saeid Hejazi, Ommoleila Molavi, Elnaz Mehdizadeh Aghdam. A Review of the in Silico Design and Development Approaches of Ras-Specific Anticancer Therapeutics. International Journal of Peptide Research and Therapeutics 2023; 30(1) doi: 10.1007/s10989-023-10578-3
|
| 103 |
Cristina Cuesta, Cristina Arévalo-Alameda, Esther Castellano. The Importance of Being PI3K in the RAS Signaling Network. Genes 2021; 12(7) doi: 10.3390/genes12071094
|
| 104 |
Elba V.M.M. Carvalho, Weslley F. Oliveira, Luana C.B.B. Coelho, Maria T.S. Correia. Lectins as mitosis stimulating factors: Briefly reviewed. Life Sciences 2018; 207 doi: 10.1016/j.lfs.2018.06.003
|
| 105 |
Reiko Satow, Tamaki Hirano, Ryosuke Batori, Tomomi Nakamura, Yumi Murayama, Kiyoko Fukami. Phospholipase Cδ1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells. Proceedings of the National Academy of Sciences 2014; 111(37) doi: 10.1073/pnas.1405374111
|
| 106 |
André Fonseca, Sara Ventura Ramalhete, André Mestre, Ricardo Pires das Neves, Ana Marreiros, Pedro Castelo-Branco, Vânia Palma Roberto. Identification of colorectal cancer associated biomarkers: an integrated analysis of miRNA expression. Aging 2021; 13(18) doi: 10.18632/aging.203556
|
| 107 |
Sujata Paul, El Bethel Lalthavel Hmar, Hemanta Kumar Sharma. Understanding the mechanism of ulcerative colitis-induced colorectal cancer and revealing the potential of Dillenia Indica in its management. European Journal of Medicinal Chemistry Reports 2024; 11 doi: 10.1016/j.ejmcr.2024.100161
|
| 108 |
Bo-Xin Zheng, Ze-Xin Chen, Ya-Kun Wang, Jia-Peng Dong, Meng-Ting She, Ying-Ying Zheng, Yao-Xun Zeng, Wen-De Zheng, Wei Long, Wing-Leung Wong. Translational Suppression of KRAS and NRAS via RNA G-Quadruplex-Targeting Small Molecules for Colorectal Cancer Therapy. Journal of Medicinal Chemistry 2026; 69(3) doi: 10.1021/acs.jmedchem.5c03088
|
| 109 |
Jing-Jing Wang, Qing-Yun Chong, Xin-Bao Sun, Ming-Liang You, Vijay Pandey, Yi-Jun Chen, Qiu-Shi Zhuang, Dong-Xu Liu, Lan Ma, Zheng-Sheng Wu, Tao Zhu, Peter E. Lobie. Autocrine hGH stimulates oncogenicity, epithelial-mesenchymal transition and cancer stem cell-like behavior in human colorectal carcinoma. Oncotarget 2017; 8(61) doi: 10.18632/oncotarget.21812
|
| 110 |
Agata Olejniczak, Magdalena Szaryńska, Zbigniew Kmieć. In vitro characterization of spheres derived from colorectal cancer cell lines. International Journal of Oncology 2017; doi: 10.3892/ijo.2017.4206
|
| 111 |
Jingxuan Xu, Jian Wen, Shuangquan Li, Xian Shen, Tao You, Yingpeng Huang, Chongyong Xu, Yaping Zhao. Immune-Related Nine-MicroRNA Signature for Predicting the Prognosis of Gastric Cancer. Frontiers in Genetics 2021; 12 doi: 10.3389/fgene.2021.690598
|
| 112 |
Amani M. Harrandah, Rodrigo A. Mora, Edward K.L. Chan. Emerging microRNAs in cancer diagnosis, progression, and immune surveillance. Cancer Letters 2018; 438 doi: 10.1016/j.canlet.2018.09.019
|
| 113 |
. 2014; doi: 10.70675/761dc689zc907z41a1z8f5ez85bf9544c19c
|
| 114 |
Veronica Aran, Manoela Heringer, Paulo Jose da Mata, Leandro Kasuki, Renan Lyra Miranda, Felipe Andreiuolo, Leila Chimelli, Paulo Niemeyer Filho, Monica Roberto Gadelha, Vivaldo Moura Neto. Identification of mutant K-RAS in pituitary macroadenoma. Pituitary 2021; 24(5) doi: 10.1007/s11102-021-01151-6
|
| 115 |
Anbarasu Kumaraswamy, Anitha Mamidi, Pavitra Desai, Ananthi Sivagnanam, Lakshmi Revathi Perumalsamy, Chandrasekaran Ramakrishnan, Michael Gromiha, Krishnaraj Rajalingam, Sundarasamy Mahalingam. The non-enzymatic RAS effector RASSF7 inhibits oncogenic c-Myc function. Journal of Biological Chemistry 2018; 293(40) doi: 10.1074/jbc.RA118.004452
|
| 116 |
Madison M. Crutcher, Trevor R. Baybutt, Jessica S. Kopenhaver, Adam E. Snook, Scott A. Waldman. Emerging drug targets for colon cancer: A preclinical assessment. Expert Opinion on Therapeutic Targets 2022; 26(3) doi: 10.1080/14728222.2022.2039119
|
| 117 |
Shiran Shapira, Ilana Boustanai, Dina Kazanov, Marina Ben Shimon, Ahmad Fokra, Nadir Arber. Innovative dual system approach for selective eradication of cancer cells using viral-based delivery of natural bacterial toxin–antitoxin system. Oncogene 2021; 40(31) doi: 10.1038/s41388-021-01792-8
|
| 118 |
Jeremy Jeack Ceen Ng, Zhi Xuan Low, Larsen Alessandro, Jung Yin Fong, Audrey Onn Yi Au Yong, Minn-E Ng, Michelle Yee Mun Teo, Hok Chai Yam, Lionel Lian Aun In. Recombinant cell penetrating peptides and intrabodies targeting membrane-bound mutated KRAS antigens. Asia Pacific Journal of Molecular Biology and Biotechnology 2022; doi: 10.35118/apjmbb.2022.030.2.06
|
| 119 |
Mayank Jauhri, Akanksha Bhatnagar, Satish Gupta, Manasa BP, Sachin Minhas, Yogender Shokeen, Shyam Aggarwal. Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing–based cohort study. Tumor Biology 2017; 39(2) doi: 10.1177/1010428317692265
|
| 120 |
Pasi A. Jänne, Melissa L. Johnson, Jin Li, Shubham Pant, Ulrich Dünzinger, Luis Ilia, Kerstin Möldner, Jae Eui Soh, Noboru Yamamoto. The SOS1 Inhibitor BI 1701963 as Monotherapy or in Combination with Trametinib in Patients with KRAS Mutation-Positive Solid Tumors. Clinical Cancer Research 2026; 32(15) doi: 10.1158/1078-0432.CCR-25-3725
|
| 121 |
Yi‐Jung Ho, Yueh‐Min Lin, Yen‐Chi Huang, Jungshan Chang, Kun‐Tu Yeh, Liang‐In Lin, Zhiyuan Gong, Tsai‐Yu Tzeng, Jeng‐Wei Lu. Significance of histone methyltransferase SETDB1 expression in colon adenocarcinoma. APMIS 2017; 125(11) doi: 10.1111/apm.12745
|
| 122 |
Rupesh Kumar, Maged Mostafa Mahmoud, Hanaa M. Tashkandi, Shafiul Haque, Steve Harakeh, Kalaiarasan Ponnusamy, Shazia Haider. Combinatorial Network of Transcriptional and miRNA Regulation in Colorectal Cancer. International Journal of Molecular Sciences 2023; 24(6) doi: 10.3390/ijms24065356
|
| 123 |
Pranathi Tata, Piyush Gondaliya, Aditya Sunkaria, Akshay Srivastava, Kiran Kalia. Modulation of CD44, EGFR and RAC Pathway Genes (WAVE Complex) in Epithelial Cancers. Current Pharmaceutical Design 2019; 25(8) doi: 10.2174/1381612825666190222143044
|