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For: Saraiva MR, Rosa I, Claro I. Early-onset colorectal cancer: A review of current knowledge. World J Gastroenterol 2023; 29(8): 1289-1303 [PMID: 36925459 DOI: 10.3748/wjg.v29.i8.1289]
URL: https://www.wjgnet.com/1948-5204/full/v29/i8/1289.htm
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1
Elizabeth Sun, Xiangzhu Zhu, Reid M Ness, Harvey J Murff, Shan Sun, Chang Yu, Lei Fan, M. Andrea Azcarate-Peril, Martha J Shrubsole, Qi Dai. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trialThe American Journal of Clinical Nutrition 2025; 122(5) doi: 10.1016/j.ajcnut.2025.09.011
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Álvaro Esteban Ruiz-Grajales, Manuela María Orozco-Puerta, Senshuang Zheng, Geertruida H․ de Bock, Juan Camilo Correa-Cote, Esteban Castrillón-Martínez. Clinical and pathological differences between early- and late-onset colorectal cancer and determinants of one-year all-cause mortality among advanced-stage patients: a retrospective cohort study in Medellín, ColombiaCancer Treatment and Research Communications 2024; 39 doi: 10.1016/j.ctarc.2024.100797
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Majed Ramadan. Assessing the contribution of nine preventable risk factors attributed to the burden of early onset colorectal cancer in Gulf Cooperation Council (GCC) countriesPreventive Medicine Reports 2023; 35 doi: 10.1016/j.pmedr.2023.102389
4
Caterina Foppa, Annalisa Maroli, Antonio Luberto, Carlotta La Raja, Paola Spaggiari, Cristiana Bonifacio, Stefano De Zanet, Marco Montorsi, Salvatore Piscuoglio, Luigi Maria Terracciano, Armando Santoro, Antonino Spinelli. Early Age of Onset Is an Independent Predictor for a Worse Response to Neoadjuvant Therapies in Sporadic Rectal Cancer PatientsCancers 2023; 15(14) doi: 10.3390/cancers15143750
5
平 盛. Progress in Surgical Treatment of Colorectal CancerAdvances in Clinical Medicine 2023; 13(11) doi: 10.12677/ACM.2023.13112510
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Zhengyuan Zhou, Linda Kleis, Ana Depetris-Chauvin, Stefanie Jaskulski, Victoria Damerell, Karin B Michels, Biljana Gigic, Ute Nöthlings, Gianni Panagiotou. Beneficial microbiome and diet interplay in early-onset colorectal cancerEMBO Molecular Medicine 2024; 17(1) doi: 10.1038/s44321-024-00177-0
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Jian Li, De Ming Tong, Peng Lv, Peng Xu, Cheng Zhang. Individualised prediction of chemotherapy benefit in early-onset colorectal cancerDiscover Oncology 2024; 15(1) doi: 10.1007/s12672-024-01490-3
8
Wanqing Tu, Leilai Xu. Refining cost-effectiveness modeling of colorectal cancer screening in average-risk Asian populations: implications of risk-based stratification and free screening policiesGastrointestinal Endoscopy 2026; 103(5) doi: 10.1016/j.gie.2025.10.040
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Cristiano Spada, Sara Sofia De Lucia. Waye's Colonoscopy2026;  doi: 10.1002/9781394220281.ch15
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Lei Zhang, Kexuan Wang, Guanghui Wang, Chenhao Hu, Chao Yin, Yujie Li, Lin Wang, Junjun She, Zhigang Wu, Feiyu Shi. Comparison of clinical outcomes and quality of life for robotic versus laparoscopic surgery in elderly patients with mid-low rectal cancer: a multicenter cohort study with inverse probability of treatment weighting analysisFrontiers in Oncology 2026; 16 doi: 10.3389/fonc.2026.1809161
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Xing Sun, Jingang Ma, Yang Li. Efficient polyp detection algorithm based on deep learningScandinavian Journal of Gastroenterology 2025; 60(6) doi: 10.1080/00365521.2025.2503297
12
Juan Pablo Campana, Tomas Cifone, Esteban Gonzalez Salazar, Gustavo Rossi, Ricardo Mentz, Carlos Vaccaro, Ma. Dolores Daneri, Juan Carlos Patron Uriburu, Mariano Cillo, Hernan Ruiz, Diego Estefania, Nicolas Rotholtz, Camila Bras Harriott, Maximiliano Bun, Fiorella Campagno, Augusto Carrie, Mateo Santillan, Nicolás Avellaneda, Carina Chwat, Flavia Alexandre, Guillermo Rosato, Diego Valli, Mauro Ramirez Duarte, Agustín Alesandrini, Juan Perriello, Nadia Miranda, Fabio Leiro, Martina Bigerna, Romina Bianchi, Gabriel Gondolesi, Marcos Gonzalez, Lisandro Moreno, Magdalena Bozzetti, Macarena Lucas, Juan Manuel Sotelo, Ana Ines Leone, Pamela Jacinto, Alejandro Canelas, Pablo Farina, Carlos Miguel Lumi, Karina Collia Avila, Emiliano Caruso, Juan Pablo Muñoz, Natalia Mira Gesto, Milagros Marasca, Julieta Espino, Mauro Trama, Mariela Cedermas, Pablo Arbios, Gerardo Zanoni, Javier Minoldo, Guillermo Vallejos Pereira, Juan Manuel Giordanino, Luz Maria Salinas Sosa, Agustin Pierotti, Flavia Gorreta, Ezequiel Danielli, Gerardo Martín Rodriguez, Camilo Sebastian Canesin, Diego Bertani, Walther Minati, Eduardo Carrozzo, Rodrigo Molina, Carlos Robales, Adrian Francisco, Maria Paula Hendl, Gustavo Marcucci, Lisandro Lorenzi, Nestor Marchetti, Juan Gigli, Federico Posner, Marcelo Schor, Ruben Balmaceda, Martin Galvarini, Yanina Agnella, María Manuela Barranco, Franco Paredes, Sabrina Velásquez, Javier Girardini, Juliana Sesma, Juan Pablo Campana, Tomas Cifone, Esteban Gonzalez Salazar, Gustavo Rossi, Ricardo Mentz, Carlos Vaccaro, Ma Dolores Daneri, Juan Carlos Patron Uriburu, Mariano Cillo, Hernan Ruiz, Diego Estefania, Nicolas Rotholtz, Camila Bras Harriott, Maximiliano Bun, Fiorella Campagno, Augusto Carrie, Mateo Santillan, Nicolás Avellaneda, Carina Chwat, Flavia Alexandre, Guillermo Rosato, Diego Valli, Mauro Ramirez Duarte, Agustín Alesandrini, Juan Perriello, Nadia Miranda, Fabio Leiro, Martina Bigerna, Romina Bianchi, Gabriel Gondolesi, Marcos Gonzalez, Lisandro Moreno, Magdalena Bozzetti, Macarena Lucas, Juan Manuel Sotelo, Ana Ines Leone, Pamela Jacinto, Alejandro Canelas, Pablo Farina, Carlos Miguel Lumi, Karina Collia Avila, Emiliano Caruso, Juan Pablo Muñoz, Natalia Mira Gesto, Milagros Marasca, Julieta Espino, Mauro Trama, Mariela Cedermas, Pablo Arbios, Gerardo Zanoni, Javier Minoldo, Guillermo Vallejos Pereira, Juan Manuel Giordanino, Luz Maria Salinas Sosa, Agustin Pierotti, Flavia Gorreta, Ezequiel Danielli, Gerardo Martín Rodriguez, Camilo Sebastian Canesin, Diego Bertani, Walther Minati, Eduardo Carrozzo, Rodrigo Molina, Carlos Robales, Adrian Francisco, Maria Paula Hendl, Gustavo Marcucci, Lisandro Lorenzi, Nestor Marchetti, Juan Gigli, Federico Posner, Marcelo Schor, Ruben Balmaceda, Martin Galvarini, Yanina Agnella, María Manuela Barranco, Franco Paredes, Sabrina Velásquez, Javier Girardini, Juliana Sesma. Early-onset colorectal cancer in Argentina: a multicenter surgical analysis of incidence, stage, and metastatic patternsThe Lancet Regional Health - Americas 2026; 56 doi: 10.1016/j.lana.2026.101415
13
Moniek van Zutphen, Auke J. C. F. Verkaar, Fränzel J. B. van Duijnhoven, Trudy Voortman, Monica L. Baskin, Rajiv Chowdhury, Ellen Copson, Sarah J. Lewis, Lynette Hill, John Krebs, Matty P. Weijenberg, Jacob C. Seidell, Yikyung Park, Jennifer L. Baker, Mojgan Amiri, Tosca O. E. de Crom, Erand Llanaj, Amber Meulenbeld, Macarena Lara, Yuchan Mou, Vanessa L. Z. Gordon‐Dseagu, Esther M. González‐Gil, Georgios Markozannes, Konstantinos K. Tsilidis, Doris S. M. Chan, Ellen Kampman, Dieuwertje E. Kok. Early‐life anthropometry and colorectal cancer risk in adulthood: Global Cancer Update Programme (CUP Global) systematic literature review and meta‐analysis of prospective studiesInternational Journal of Cancer 2025; 157(6) doi: 10.1002/ijc.35461
14
Sha Luo, Jiajun Xu, Chune Mo, Weiwei Gong, Chunhong Li, Xianliang Hou, Minglin Ou. High-throughput sequencing reveals twelve cell death pattern prognostic target genes as potential drug-response-associated genes in the treatment of colorectal cancer cells with palmatine hydrochlorideOncologie 2025; 27(1) doi: 10.1515/oncologie-2024-0378
15
Vlad Alexandru Ionescu, Gina Gheorghe, Teodor Florin Georgescu, Vlad Buica, Mihai-Stefan Catanescu, Iris-Andreea Cercel, Beatrice Budeanu, Mihail Budan, Nicolae Bacalbasa, Camelia Diaconu. Exploring the Role of the Gut Microbiota in Colorectal Cancer DevelopmentGastrointestinal Disorders 2024; 6(2) doi: 10.3390/gidisord6020036
16
Jinlan Di, Jianlei Liu, Xiaochun Zhang. Mechanisms Underlying Immunotherapy Resistance in Microsatellite-Stable Colorectal CancerBratislava Medical Journal 2026; 127(3) doi: 10.1007/s44411-026-00524-2
17
Jerrald Lau, Alyssa Ng, Wei-Ling Koh, Kai-Yin Lee, Nan Luo, Ker-Kan Tan. The impact of colorectal cancer on quality of life of younger adults: A qualitative longitudinal approachEuropean Journal of Surgical Oncology 2026; 52(1) doi: 10.1016/j.ejso.2025.111169
18
Sana Iqbal, Asim Pervaiz, Shaukat Ali, Munir Ahmad Bhinder, Faheem Shahzad, Bushra Ijaz, Mahmood S. Choudhery. Experimental data supports antineoplastic effects of silkworm protein sericin against colorectal cancer cellsMedical Oncology 2025; 43(1) doi: 10.1007/s12032-025-03131-3
19
Alexandr Stratulat, Alejandro Valverde, Laura Mariën, Ken Op de Beeck, Guy Van Camp, Karolien De Wael. Rapid detection of NPY methylation in colorectal cancer using a singlet oxygen-based photoelectrochemical ratiometric bio-platformAnalytica Chimica Acta 2025; 1370 doi: 10.1016/j.aca.2025.344381
20
Maria F. Gomez Morales, Stephanie R. Hogue, Scott Pitcher, Daniel Jeong, Ivana Radosavljevic, Amalia Stefanou, Seth I. Felder, Jessica R. Burns, Scot E. Dowd, Emily Vogtmann, Rashmi Sinha, Liang Wang, Xuefeng Wang, Jennifer B. Permuth, Cynthia L. Sears, Shaneda Warren Andersen, K. Leigh Greathouse, Jacob K. Kresovich, Mark S. Friedman, Erin M. Siegel, Doratha A. Byrd. Survival implications of the age-associated tumor and normal adjacent tissue microbiome among colorectal cancer patientsGut Pathogens 2025; 17(1) doi: 10.1186/s13099-025-00773-6
21
Eugene Annor, Joseph Atarere, Quarshie Glover, Nneoma Ubah, Chinenye Odo, Yakubu Bene-Alhasan, Vwaire Orhurhu, Jamal Hasoon, Wisdom Chinonyelu Ufondu, Moyasar Osman, Christopher Thompson. E-cigarette Smoking and Colorectal Cancer ScreeningAmerican Journal of Health Promotion 2025; 39(4) doi: 10.1177/08901171241304726
22
Marjan Ghiyasvand, Ardeshir Hesampour, Hossein Dabiri, Javad Arasteh. Anticancer Effects of Escherichia Coli-Derived Outer Membrane Vesicles Against Colorectal CancerReports of Biochemistry and Molecular Biology 2024; 13(3) doi: 10.61186/rbmb.13.3.438
23
Xin Guo, Saisai Tian, Xinxing Li, Hongwei Zhang, Anqi Wang, Yan Jin, Ce Bian, Jiayi Lin, Sanhong Liu, Min Tang, Lijun Zhang, Xin Luan, Haiyang Zhou, Weidong Zhang. Integrated Multi‐Omics Profiling to Characterize Molecular Subtypes and Reveal Potential Therapeutic Strategies for Colorectal CancerMedComm 2025; 6(12) doi: 10.1002/mco2.70492
24
Yu-Qing Gong, Chun-Jing Lu, Yan-Ru Xiao, Jin-Yan Zhang, Zhong Xu, Ji Li, Wei-Feng Huang. Epidemiological trends of early-onset gastrointestinal cancers from 1990 to 2021 and predictions for 2036: analysis from the global burden of disease study 2021Annals of Medicine 2025; 57(1) doi: 10.1080/07853890.2025.2555518
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Marwh G. Aldriwesh, Amer R. Aljaian, Khalid M. Alorf, Mohammed A. Bayounis, Yazeed H. Alrayani, Winnie Philip, Mohammed Algarni, Nahar A. Alselaim, Raniah S. Alotibi. Comparative analysis of the clinical aspects of colorectal cancer in young adult and older adult patients in Saudi ArabiaFrontiers in Oncology 2024; 14 doi: 10.3389/fonc.2024.1460636
26
Miquel Kraft, Annalisa Maroli, Meritxell Pera, Elsa García-Möller, Gianluca Pellino, Antonino Spinelli, Eloy Espín-Basany. Subclinical anxiety and depression and postoperative complications after major colorectal surgery: A 2-center studySurgery 2026; 196 doi: 10.1016/j.surg.2026.110317
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Shaina Ailawadi, David C. Kaelber, Abbinaya Elangovan. Early-Onset Colorectal Cancer: A Review of Current Insights and a Call for ActionBiomedicines 2025; 13(7) doi: 10.3390/biomedicines13071572
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Ami E Sedani. #CRCandMe: results of a pre-post quasi-experimental study of a mass media campaign to increase early-onset colorectal cancer awareness in Utah and WisconsinAmerican Journal of Cancer Research 2024; 14(8) doi: 10.62347/PGYM7724
29
Natalia Kurowska, Maria Książek, Paulina Borkowska, Barbara Strzałka-Mrozik. Cell Line–Dependent Cell Death Pathways Induced by Thymoquinone in Colorectal Cancer CellsMolecules 2026; 31(3) doi: 10.3390/molecules31030512
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Saleh Alessy, Badr Al-Bawardy, Abeer Alabdullah, Duna Barakeh, Mayar Alatout, Sara Khan, Osamah Altamimi, Shams A. AlBader, Aljohara S. Alasheikh, Mohammad Alhassoun, Layan A. Alsubki, Basmah B Khoja, Abdulmohsen Alshammari, Nawaf AlEnaz, Saleh Alorainy, Norah Bin Sulaiman, Ahmad Alharbi, Waleed Alomaim, Manal Bukhary, Saleh A. Alqahtani. Comparison of early-onset and average-onset colorectal cancer in Saudi Arabia: A multicenter retrospective cohort studySaudi Journal of Gastroenterology 2026;  doi: 10.4103/sjg.sjg_51_26
31
Lana Jajac Brucic, Vesna Bisof, Majana Soce, Marko Skelin, Ivan Krecak, Andjela Nadinic, Branka Vrbicic, Zivana Puljiz, Suzana Hancic, Slavko Gasparov. Polo-like Kinase 1 Expression as a Biomarker in Colorectal Cancer: A Retrospective Two-Center StudyBiomedicines 2024; 13(1) doi: 10.3390/biomedicines13010054
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Andrzej S Tarnawski. Editor-in-Chief articles of choice and comments at the year-end of 2023World Journal of Gastroenterology 2024; 30(1): 1-8 doi: 10.3748/wjg.v30.i1.1
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Yazan Abboud, Madison Fraser, Imran Qureshi, Kaveh Hajifathalian. Early-Onset Colorectal Cancer: Are Neuroendocrine Tumors or Adenocarcinomas the Culprit? Analysis of the Largest U.S. Cancer Incidence Database, 2001–2020Journal of Clinical Medicine 2024; 13(4) doi: 10.3390/jcm13041098
34
Thomas Lawler, Lisa Parlato, Shaneda Warren Andersen. The histological and molecular characteristics of early-onset colorectal cancer: a systematic review and meta-analysisFrontiers in Oncology 2024; 14 doi: 10.3389/fonc.2024.1349572
35
Stefanie BREZINA, Gernot LEEB, Andreas BAIERL, Evelyn GRÄF, Monika HACKL, Philipp HOFER, Harald LANG, Michaela KLEIN, Karl MACH, Remy SCHWARZER, Wilhelm WLASSITS, Andreas PÜSPÖK, Andrea GSUR. Evaluation of the “Burgenland PREvention trial of colorectal cancer Disease with ImmunologiCal Testing” (B-PREDICT)—a population-based colorectal cancer screening programBMC Gastroenterology 2024; 24(1) doi: 10.1186/s12876-024-03242-7
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Laudy Chehade, Kristel Dagher, Ali Shamseddine. Tailoring treatment for locally advanced rectal cancerCancer Treatment and Research Communications 2024; 41 doi: 10.1016/j.ctarc.2024.100847
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Hui Lionel Raphael Chen, Qingqing Dawn Chong, Brenda Tay, Siqin Zhou, Evelyn Yi Ting Wong, Isaac Seow-En, Ker Kan Tan, Yi Wang, Adeline Seow, Kwong-Wei Emile Tan, Bee Huat Iain Tan, Sze Huey Tan. Trends in Early-Onset Colorectal Cancer in Singapore: Epidemiological Study of a Multiethnic PopulationJMIR Public Health and Surveillance 2025; 11 doi: 10.2196/62835
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Shiva Darabi, Fatemeh Keshavarzi, Parviz Ashtari, Farahnaz Motamedi Sedeh, Behrouz Alirezapour. The effects of gut microbiota-derived short-chain fatty acids (SCFAs) on human colon cancer cells: An in vitro studyJournal of Genetic Engineering and Biotechnology 2025; 23(4) doi: 10.1016/j.jgeb.2025.100610
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Sameh Hany Emile, Nir Horesh, Zoe Garoufalia, Rachel Gefen, Justin Dourado, Marylise Boutros, Steven D. Wexner. Non‐Colorectal Cancer‐Related Deaths in Patients With Early‐Onset Colorectal Cancer: A Population‐Based StudyJournal of Surgical Oncology 2025; 132(8) doi: 10.1002/jso.70118
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Betül Keskinkılıç Yağız, Metin Yalaza. Sağlık Çalışanlarının Kolorektal Kanser Tarama Programına Yönelik Farkındalık ve Davranış Düzeyinin DeğerlendirilmesiHarran Üniversitesi Tıp Fakültesi Dergisi 2024; 21(3) doi: 10.35440/hutfd.1540876
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Amna Fareed, Mazhar Iqbal, Syed Shafqatullah, Naeem Khan, Resham Ali, Raja Jawad, Ali Muhammad Rahuja, Sarkhail A Sayar. Presentation of Rectal Cancer Among Young Adults in a Tertiary Care CenterCureus 2025;  doi: 10.7759/cureus.91992
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Thanathip Suenghataiphorn, Peenaprapa Tangpradubkiat, Vitchapong Prasitsumrit, Narathorn Kulthamrongsri, Pojsakorn Danpanichkul, Rohit Singhania. State-level burden of early onset colorectal cancer in the US: a Global Burden of Disease study, 1980 to 2021Baylor University Medical Center Proceedings 2026;  doi: 10.1080/08998280.2026.2651609
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Huanqing Li, Songhua Bei, Yanqing Mo, Li Feng. Theaflavins Inhibit Proliferation and Glycolysis of Colorectal Cancer Cells by Downregulating DDIT4Drug Development Research 2025; 86(6) doi: 10.1002/ddr.70151
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Chun-Kai Liao, Yu-Jen Hsu, Yih-Jong Chern, Yen-Lin Yu, Yueh-Chen Lin, Pao-Shiu Hsieh, Jy-Ming Chiang, Jeng-Fu You. Differences in characteristics and outcomes between early-onset colorectal cancer and late-onset colorectal cancersEuropean Journal of Surgical Oncology 2024; 50(12) doi: 10.1016/j.ejso.2024.108687
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Elahe Jafari, Seyedeh Zahra Bahojb Mahdavi, Haniyeh Azimi Hasani, Mohammad Yousef Memar, Omid Pourbagherian, Sahar Safaei, Amir Ali Mokhtarzadeh, Golamreza Dehghan, Morteza Eskandani. α-pinene effects on the anticancer properties of Lactobacillus acidophilus probiotics against colorectal cancer cellsBMC Microbiology 2026; 26(1) doi: 10.1186/s12866-025-04639-4
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John K Triantafillidis, Konstantinos Georgiou, Manousos M Konstadoulakis, Apostolos E Papalois. Early-onset gastrointestinal cancer: An epidemiological reality with great significance and implicationsWorld Journal of Gastrointestinal Oncology 2024; 16(3): 583-597 doi: 10.4251/wjgo.v16.i3.583
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Hossam Elfeki, Reem A. Alharbi, Therese Juul, Asbjørn M. Drewes, Peter Christensen, Søren Laurberg, Katrine J. Emmertsen. Chronic pain after colorectal cancer treatment: A population‐based cross‐sectional studyColorectal Disease 2025; 27(2) doi: 10.1111/codi.17296
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Xinlong Cui, Naihan Cao, Shouyuan Tian, Yi Liu, Jie Xiang. A Prospective Nested Case-Control Study of Risk Factors for Postoperative Delirium in Elderly Patients with Colorectal CancerClinical Interventions in Aging 2025;  doi: 10.2147/CIA.S507668
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Majed Ramadan, Hanin Ghamdi, Doaa Aboalola, Noha Alorainan, Ragad Alsalmi, Ahmed Afash, Albaraa Hariri, Atheer Alboloshi, Alaa Samkari, Rawiah Alsiary. Disease burden and projection of total and early-onset colorectal cancer in Gulf cooperation council countries from 1990 to 2019Neoplasia 2024; 51 doi: 10.1016/j.neo.2024.100988
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Derick Okwan-Duodu, Arun R. Pandiri, David J. Adams. Not All Carcinogens Are Directly Mutagenic: A Holistic View of the Environmental Exposure–Cancer Connection Annual Review of Cancer Biology 2025; 9(1) doi: 10.1146/annurev-cancerbio-060424-052905
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Wenpeng Han, Yanyan Liu, Bo Zhang, Jing Liu, Mingxia Sun, Hongqing Zhuo. RETRACTED: Construction and validation of nomogram model for endoscopic submucosal dissection in patients with early colorectal cancer based on intestinal microflora and clinical pathological parametersFrontiers in Medicine 2025; 12 doi: 10.3389/fmed.2025.1604257
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Manasawee Tanariyakul, Chalothorn Wannaphut, Toshiaki Takahashi, Ryon Nakasone, Jared Acoba. Comprehensive Analysis of Native Hawaiians and Other Pacific Islanders with Early Onset Colorectal CancerJournal of Gastrointestinal Cancer 2025; 56(1) doi: 10.1007/s12029-025-01278-w
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Jovana Despotović, Neda Nikolić, Tamara Babic, Milena Ugrin, Aleksandra Đikić Rom, Ana Damjanović, Aleksandra Nikolic, Sandra Dragičević. KRAS , NRAS and BRAF Mutational Landscape in Serbian Early-Onset Colorectal Cancer Patients Cancer Control 2026; 33 doi: 10.1177/10732748261426049
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Le Trung Kien, Tran Duc Huy, Nguyen Huu Thinh, Ung Van Viet, Tran Thien Trung. Survival outcomes and prognostic factors in early-onset colorectal cancerVietnam Journal of Endolaparoscopic Surgey 2025; 15(3) doi: 10.51199/vjsel.2025.3.13
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E. Ghulam, M. Ramadan. Age–period–cohort analysis of colorectal cancer mortality in Saudi Arabia from 1990 to 2019Public Health 2024; 228 doi: 10.1016/j.puhe.2023.11.033
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Qian-Nan Wang, Xiao Zhang, Lan-Lan Feng, Na Ning, Fu-Qin Zhang, Jia-Min Liang, Wei Zhang, Li Gong. Estrogen Receptor May Play Important Role in Gender Differences of Early-Onset Colorectal CancerClinical Colorectal Cancer 2026; 25(1) doi: 10.1016/j.clcc.2025.10.008
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Erman Akkus, Beliz Bahar Karaoğlan, Mehmet Kayaalp, Utkucan Turmuş, Cihangir Akyol, Güngör Utkan. Stage‐specific characterization of “early‐onset colorectal cancer”: Localized and synchronous metastatic diseaseInternational Journal of Cancer 2025; 156(12) doi: 10.1002/ijc.35336
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Fauzia Ullah, Ashwathy Balachandran Pillai, Najiullah Omar, Danai Dima, Seema Harichand. Early-Onset Colorectal Cancer: Current InsightsCancers 2023; 15(12) doi: 10.3390/cancers15123202
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Ragala Venkata Nandha, A. R. Heamchandsaravanan, Priyadarshene Kamalanathan, Prabu Dhandapani, Anandan Balakrishnan. Microbiota and Dietary Mediators in Colon Cancer Prevention and Treatment2024;  doi: 10.1007/978-981-96-0297-1_4
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Enoch Xun Jiang, Giulio Quarta, Olivia Delau, Aasma Shaukat. Mutations in Exon 29 of Ring Finger Protein 213 Are Associated with Early-Onset Colorectal CancerDigestive Diseases and Sciences 2026;  doi: 10.1007/s10620-026-09784-y
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Muhammad S Khan, Azwa Ali, Murk Niaz, Raheena Hassan, Bushra Shirazi, Raja Taha Yaseen Khan. Comparative Analysis of Tumor Characteristics, Treatment Response, and Oncological Outcomes in Early-Onset Versus Late-Onset Colorectal Cancer: A Retrospective Cohort StudyCureus 2025;  doi: 10.7759/cureus.82975
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Luis D. Borrero‐Garcia, Marilyn Moró‐Carrión, Carlos R. Torres‐Cintrón, Hilmaris Centeno‐Girona, Victoria Perez, Taymaraliz Santos‐Colón, María González‐Pons. Disparities in Colorectal Cancer Incidence Trends Among Hispanics Living in Puerto Rico (2000–2021): A Comparison With Surveillance, Epidemiology, and End Results (SEER) DatabaseCancer Medicine 2025; 14(8) doi: 10.1002/cam4.70851
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Haitham Al-Madhagi. Integrative transcriptomics analysis of early-onset and late-onset colorectal cancerInformatics in Medicine Unlocked 2023; 43 doi: 10.1016/j.imu.2023.101408
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Berenice Carbajal-López, Jossimar Coronel-Hernández, Marytere Herrera, Erika Ruiz-Garcia, Sayako M. Miyagui-Adame, Consuelo Diaz-Romero, Eduardo Osiris Madrigal-Santillán, Priscila Morales Esponda-Mendoza, Carlos Pérez-Plasencia, Germán Calderillo-Ruiz. Age as a Predictor of Overall Survival in Colorectal CancerDiagnostics 2024; 14(22) doi: 10.3390/diagnostics14222550
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Alexandra Sala, Lisa van den Driest, Nicholas J. W. Rattray, Caroline H. Johnson, James M. Cameron, Sajid A. Khan, David S. Palmer, Matthew J. Baker. Colorectal cancer molecular profiling: Opportunities for early detectionClinical and Translational Medicine 2025; 15(10) doi: 10.1002/ctm2.70474
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Yiwei Yuan, Zhiqing Wang, Xiucheng Zhang, Yichao Luo, Shuya Lin, Yang Bai, Zhenhui Peng. Exploring Community-Powered Conversational Agent for Health Knowledge Acquisition: A Case Study in Colorectal CancerProceedings of the 2025 International Conference on Human-Engaged Computing 2025;  doi: 10.1145/3786995.3787015
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Suzanne Poulgrain, Ted Gibbons, Cian O’Leary, Sophie Feng, Vikram Jain, Connor Gerard O’Leary. Colorectal cancer in pregnancy: case discussions and real-world data as well as literature review on current knowledgeThe Oncologist 2025; 30(7) doi: 10.1093/oncolo/oyaf097
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D. Arriaga-Izabal, F. Morales-Lazcano, U.A. Angulo-Zamudio, A. Canizalez-Román, N. León-Sicairos. Prevalencia y características clínicas del adenocarcinoma colorrectal en los pacientes jóvenes en México: revisión sistemática y metaanálisisRevista de Gastroenterología de México 2026;  doi: 10.1016/j.rgmx.2025.12.003
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Tsung‐Kun Lin, Wei‐Yao Wang, Jing‐Yang Huang, Yeu‐Sheng Tyan, Mei‐Chun Chen, Gwo‐Ping Jong, Dorji Harnod. Risk of Incident Colorectal Carcinoma in Patients With Type 2 Diabetes on SGLT‐2 Inhibitor UsersPharmacoepidemiology and Drug Safety 2026; 35(3) doi: 10.1002/pds.70348
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Salma Khan, Nolberto Jaramillo , Adrianus J Ekelmans, David J Samson, Mikaiel J Ebanks, Samantha Norden, Ryan Bendl, James Clarke, Madalyn G Neuwirth. National Trends in Rectal Cancer Among Younger Patients: A National Cancer Database AnalysisCureus 2026;  doi: 10.7759/cureus.107699
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Virginia Constantinou, Constantina Constantinou. Focusing on colorectal cancer in young adults (Review)Molecular and Clinical Oncology 2023; 20(1) doi: 10.3892/mco.2023.2706
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Moeez Maqbool, Aden Khan, Areej Shahzad, Zouina Sarfraz, Azza Sarfraz, Hinna Aftab, Ali Jaan. Predictive biomarkers for colorectal cancer: a state-of-the-art systematic reviewBiomarkers 2023; 28(6) doi: 10.1080/1354750X.2023.2247185
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Huda Mohammed, Hadeel Mohamed, Nusyba Mohamed, Rajat Sharma, Jayesh Sagar. Early Rectal Cancer: Advances in Diagnosis and Management StrategiesCancers 2025; 17(4) doi: 10.3390/cancers17040588
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