Endoscopic assessment and management of sporadic duodenal adenomas: The results of single centre multidisciplinary management

Table 1 Summary of patient demographics, adenoma morphology and investigations utilized n (%)

	Non-ampullary (n = 18)	Ampullary (n = 10)
Demographics
Median age, yr (range)	69 (47-88)	67 (48-80)
Male: female	9:9	5:5
Morphology
Pedunculated	3 (17)	1 (10)
Sessile	15 (83)	9 (90)
Median size, mm (range)	15 (9-24)	20 (10-35)
Number ≥ 20 mm	7 (39)	6 (60)
Investigations
Biopsy	7 (39)	8 (80)
EUS	3 (17)	0
ERCP	0	10 (100)

ERCP: Endoscopic retrograde cholangiopancreatography; EUS: Endoscopic ultrasound.

Table 2 Summary of treatment, biopsy and final pathology and recurrence

	Non-ampullary (n = 18)	Ampullary (n = 10)
Endoscopic treatment	15	8
Stenting
Biliary	0	2
Pancreatic	0	5
Specimen removal
Piecemeal	11	6
En bloc	4	2
Complications	0	1
Surgical resection	2	1
No treatment	1	1
Histology
	1 no dysplasia	7 low grade dysplasia
	13 low grade dysplasia	1 high grade dysplasia
	3 high grade dysplasia	1 adenocarcinoma
Concordance with biopsy	4/7	7/8
Recurrence	5	5

Table 3 Comparison of characteristics of recurrences (n = 10) vs no recurrence (n = 10)

	Recurrence (n = 10)	No recurrence (n = 10)
Non-ampullary/ ampullary	5:5	7:3
Median size (mm)	20 mm	10 mm
Treatment
Endoscopic resection	10	8
Surgical resection	0	2
Specimen retrieval
Piecemeal	8	6
En bloc	2	4
Margin positivity	9 (90%)	6 (60%)
Salvage therapy
Endoscopic resection	8
Surgical resection	2