New hope for esophageal stricture prevention: A prospective single-center trial on acellular dermal matrix

Table 1 Basic information of 20 patients

Participant	Age (yr)	Gender	Endoscopic morphology	Trauma length (cm)	Circumference of the wound	Infiltration depth	Postoperative stenosis	Occurrence of stenosis time (d)	Number of ADM used (slices)	Follow-up time (mo)	Graft mucosa survival
1	63	Male	IIa + IIc	6	2/3	Mucosal muscle layer	No	No	0	44.13	Yes
2	63	Male	IIb	5	3/4	Submucosa	No	No	0	42.73	Yes
3	58	Male	IIb	2	1/2	Mucosal muscle layer	No	No	0	40.87	Yes
4	67	Male	IIa	4	1/2	Mucosa layer	No	No	0	39.93	Yes
5	73	Female	IIb	4	4/5	Mucosal muscle layer	No	No	0	39.70	Yes
6	58	Male	IIa + IIc	5	1	Superficial submucosa	No	No	0	38.77	Yes
7	69	Female	IIa	6	4/5	Mucosal layer	No	No	0	38.53	Yes
8	69	Female	IIa	5	3/4	Mucosal layer	Yes	98	0	37.83	Yes
9	56	Male	IIa + IIc	8	1	Submucosa	Yes	44	0	34.57	Yes
10	56	Male	IIa	2	2/3	Mucosal layer	No	No	1	44.90	Yes
11	65	Male	IIa + IIc	3	2/3	Mucosal muscle superficial layer	No	No	1	44.90	Yes
12	60	Male	IIc	3	2/3	Mucosal lamina propria	No	No	1	44.43	Yes
13	73	Male	IIc	5	3/5	Mucosal lamina propria	No	No	1	43.97	Yes
14	49	Male	IIc	3	1/2	Mucosal layer	No	No	1	43.97	Yes
15	73	Female	IIa	5	3/5	Mucosal muscle layer	Yes	41	4	43.50	Yes
16	66	Male	IIc	2	4/5	Mucosal layer	No	No	1	43.03	Yes
17	78	Male	IIa + IIc	5	3/4	Mucosal layer	No	No	3	42.57	Yes
18	61	Female	IIa	3	1/2	Mucosal layer	No	No	1	42.57	Yes
19	52	Female	IIa	10	1	Submucosa	Yes	62	4	42.33	Yes
20	68	Male	IIa + IIc	6	1	Mucosal lamina propria	No	No	1	38.60	Yes

ADM: Acellular dermal matrix.

Table 2 Analysis of lesions in the autologous mucosal transplantation group and acellular dermal matrix transplantation group

	Group 1 (n = 9)	Group 2 (n = 11)	P value
Gender			0.77
Male	6	8
Female	3	3
Age			0.94
≥ 60 yr	3	4
< 60 yr	6	7
Wound circumference			0.23
1/2-3/4 circumference	3	7
3/4-full circumference	6	4
Wound length			0.22
< 10 mm	0	0
10-30 mm	1	2
> 30 mm	8	9
Endoscopic morphology			0.81
IIa	3	3
IIb	3	0
IIc	0	4
IIa + IIc	3	3
Invasion depth			0.19
Mucosal layer	3	4
Lamina propria	0	3
Muscularis mucosa	3	2
Submucosa	3	1
Follow-up time (mo)	39.67 (34.57-44.13)	43.16 (38.60-44.90)	0.52

Group 1: Autologous mucous membrane transplantation group; Group 2: Acellular dermal matrix transplantation group.