Altered endocannabinoid system gene expression in inflammatory bowel disease mucosa: New perspectives in inflammatory bowel disease management

Figure 1 Gene expression levels of the significant genes belonging to the endocannabinoid system in inflammatory bowel disease. Bar graphs refer to the mean of the 2^-ΔCt values in each group, and error bars represent the SEM. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. IBD: Inflammatory bowel disease; UC: Ulcerative colitis; CD: Crohn’s disease; CTRL: Non-inflammatory bowel disease controls; NIM: Noninflamed mucosa, IM: Inflamed mucosa; CNR2: Cannabinoid receptor 2; FAAH: Fatty acid amide hydrolase; GPR: G protein-coupled receptor 18; GPR55: G protein-coupled receptor 55; PPARG: Peroxisome proliferator-activated receptor gamma; TRPV1: Transient receptor potential cation channel, subfamily V, member 1.