Moran CP, Neary B, Doherty GA. Endoscopic evaluation in diagnosis and management of inflammatory bowel disease. World J Gastrointest Endosc 2016; 8(20): 723-732 [PMID: 28042386 DOI: 10.4253/wjge.v8.i20.723]
Corresponding Author of This Article
Carthage P Moran, MB, Centre for Colorectal Disease, St. Vincent’s University Hospital and School of Medicine, University College Dublin, Elm Park, Dublin 4, D04 T6F4 Dublin, Ireland. cmoran@ucc.ie
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Dec 16, 2016; 8(20): 723-732 Published online Dec 16, 2016. doi: 10.4253/wjge.v8.i20.723
Endoscopic evaluation in diagnosis and management of inflammatory bowel disease
Carthage P Moran, Barra Neary, Glen A Doherty
Carthage P Moran, Barra Neary, Glen A Doherty, Centre for Colorectal Disease, St. Vincent’s University Hospital and School of Medicine, University College Dublin, D04 T6F4 Dublin, Ireland
Author contributions: Moran CP and Neary B performed literature review and wrote the paper; Doherty GA contributed critical revision of the manuscript for important intellectual content.
Conflict-of-interest statement: No conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Carthage P Moran, MB, Centre for Colorectal Disease, St. Vincent’s University Hospital and School of Medicine, University College Dublin, Elm Park, Dublin 4, D04 T6F4 Dublin, Ireland. cmoran@ucc.ie
Telephone: +353-1-2214134
Received: March 30, 2016 Peer-review started: April 5, 2016 First decision: June 12, 2016 Revised: August 16, 2016 Accepted: September 21, 2016 Article in press: September 22, 2016 Published online: December 16, 2016 Processing time: 259 Days and 2.4 Hours
Core Tip
Core tip: Ileo-colonoscopy remains the most important test in the diagnosis and monitoring of inflammatory bowel disease (IBD). Video capsule endoscopy shows very high sensitivity for small bowel mucosal lesions not accessible to conventional flexible endoscopes. Both techniques facilitate monitoring of response to treatment. Endoscopic activity indices are important for monitoring treatment response and can help identify patients who may benefit from treatment escalation. Colorectal cancer surveillance in patients with IBD is shifting from high frequency random biopsies, to that of high quality visual inspection and targeted biopsies of suspected dysplasia, enabled by technological advances including chromoendoscopy and high-definition endoscopes.