Recent development of optical coherence tomography for preoperative diagnosis of esophageal malignancies

doi:10.4253/wjge.v7.i9.872

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World Journal of Gastrointestinal Endoscopy

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World J Gastrointest Endosc. Jul 25, 2015; 7(9): 872-880
Published online Jul 25, 2015. doi: 10.4253/wjge.v7.i9.872

Recent development of optical coherence tomography for preoperative diagnosis of esophageal malignancies

Kaname Uno, Tomoyuki Koike, Tooru Shimosegawa

Kaname Uno, Tomoyuki Koike, Tooru Shimosegawa, Division of Gastroenterology, Tohoku University Hospital, Miyagi 981-8574, Japan

Author contributions: All authors contributed to this paper.

Conflict-of-interest statement: None.

Correspondence to: Kaname Uno, MD, PhD, Division of Gastroenterology, Tohoku University Hospital, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 981-8574, Japan. kaname@wa2.so-net.ne.jp

Telephone: +81-22-7177171 Fax: +81-22-7177174

Received: April 22, 2015
Peer-review started: April 30, 2015
First decision: May 13, 2015
Revised: May 20, 2015
Accepted: June 15, 2015
Article in press: June 16, 2015
Published online: July 25, 2015
Processing time: 103 Days and 22.3 Hours

Core Tip

Core tip: Optical coherence tomography (OCT) provides real-time cross-sectional images with extremely high resolution. We previously reported that OCT provided significantly more accurate preoperative staging of esophageal squamous carcinoma (ESCC) than endosonography. With remarkable improvements in this technology, such as three-dimensional devices with Doppler capability, for the detection of Barrett’s-associated neoplasia, the diagnostic accuracy gradually became better through enhanced visualization of structural/functional alterations in mucosal/submucosal tissue. Recent reports suggested its usefulness for targeting malignant lesions for endoscopic intervention and for predicting treatment effects. Therefore, further development of OCT should promote improved management strategies for esophageal malignancies, including ESCC.