Prospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2015; 7(5): 555-562
Published online May 16, 2015. doi: 10.4253/wjge.v7.i5.555
Polyp detection rates using magnification with narrow band imaging and white light
Nooman Gilani, Sally Stipho, James D Panetta, Sorin Petre, Michele A Young, Francisco C Ramirez
Nooman Gilani, Sally Stipho, James D Panetta, Sorin Petre, Michele A Young, Francisco C Ramirez, Section of Gastroenterology, Department of Medicine and Research, Phoenix VA Healthcare System, Scottsdale, AZ 85254, United States
Author contributions: Gilani N and Ramirez FC designed and performed the research study; Stipho S, Panetta JD, Petre S and Young MA helped to collect the data; Gilani N and Ramirez FC performed statistical analysis and wrote the paper.
Ethics approval: This study was approved by Institutional Review Board at Phoenix VA Medical Center, Arizona, United States.
Clinical trial registration: Not applicable as this was a non-randomized study.
Informed consent: All patients in the study gave informed consent for the colonoscopy. Informed consent for the study was waived by the Institutional Review Board per request due to non-randomization.
Conflict-of-interest: None.
Data sharing: Technical appendix, statistical code, and dataset available from the corresponding author at (ngilani@hotmail.com). Consent for data sharing was not obtained from the participants but the presented data are anonymized and risk of identification is low.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Nooman Gilani, MD, FACG, FASGE, AGAF, Section of Gastroenterology, Department of Medicine and Research, Phoenix VA Healthcare System, 5529. E. Angela Drive, Scottsdale, AZ 85254, United States. ngilani@hotmail.com
Telephone: +1-602-3686008
Received: November 18, 2014
Peer-review started: November 19, 2014
First decision: December 29, 2014
Revised: January 28, 2015
Accepted: February 10, 2015
Article in press: February 12, 2015
Published online: May 16, 2015
Processing time: 180 Days and 21.9 Hours
Core Tip

Core tip: The role of narrow band imaging for polyp detection is controversial. We studied 3 groups of 100 patients each, undergoing tandem colonoscopy by (1) white light followed by narrow band imaging; (2) narrow band followed by white light; and (3) white light followed by white light. Detection rate for polyps with white light used first was similar irrespective of the light used afterwards. Miss rate of polyps and adenomas was higher when narrow band imaging was used first (29.3% and 30.3%, respectively; P < 0.05). Our study suggests that the tandem nature of colonoscopy rather than the optical techniques, detects missing pathology.