©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Aug 25, 2015; 7(11): 1014-1022
Published online Aug 25, 2015. doi: 10.4253/wjge.v7.i11.1014
Published online Aug 25, 2015. doi: 10.4253/wjge.v7.i11.1014
Cell-block procedure in endoscopic ultrasound-guided-fine-needle-aspiration of gastrointestinal solid neoplastic lesions
Antonio Ieni, Valeria Barresi, Rosario Alberto Caruso, Giovanni Tuccari, Department of Human Pathology “Gaetano Barresi”, Section of Anatomic Pathology, University of Messina, Azienda Ospedaliera Universitaria “Gaetano Martino”, 98125 Messina, Italy
Paolo Todaro, Department of Human Pathology “Gaetano Barresi”, Section of Cytopathology, University of Messina, Azienda Ospedaliera Universitaria “Gaetano Martino”, 98125 Messina, Italy
Author contributions: Ieni A and Tuccari G wrote the paper; Barresi V, Todaro P and Caruso RA collected the literature data; all authors read and approved the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Correspondence to: Giovanni Tuccari, MD, Full Professor of Pathology, Department of Human Pathology “Gaetano Barresi”, Section of Anatomic Pathology, University of Messina, Azienda Ospedaliera Universitaria “Gaetano Martino”, Via Consolare Valeria 1, 98125 Messina, Italy. tuccari@unime.it
Telephone: +39-90-2212539
Received: April 12, 2015
Peer-review started: April 15, 2015
First decision: June 24, 2015
Revised: July 1, 2015
Accepted: July 29, 2015
Article in press: August 3, 2015
Published online: August 25, 2015
Processing time: 138 Days and 17.3 Hours
Peer-review started: April 15, 2015
First decision: June 24, 2015
Revised: July 1, 2015
Accepted: July 29, 2015
Article in press: August 3, 2015
Published online: August 25, 2015
Processing time: 138 Days and 17.3 Hours
Core Tip
Core tip: Cell-block procedure (CBP) represents the most suitable complement in diagnostic cytopathology of many gastrointestinal lesions. Hence this method allows high quality morphological evaluation and immunocytochemical analyses. On this way, the differential diagnosis of solid gastrointestinal neoplasms may be more easily achieved and the background of contaminant non-neoplastic gastrointestinal avoided, with an evident gain compared to the traditional cytological techniques. In the present review, the application of CBP in gastrointestinal solid lesions approached by endoscopic ultrasound-guided-fine-needle-aspiration, the methodological aspects and the accuracy of this diagnostic process are analyzed and discussed.