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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Nov 16, 2014; 6(11): 555-563
Published online Nov 16, 2014. doi: 10.4253/wjge.v6.i11.555
Published online Nov 16, 2014. doi: 10.4253/wjge.v6.i11.555
Endoscopic submucosal dissection vs endoscopic mucosal resection for early gastric cancer: A meta-analysis
Antonio Facciorusso, Matteo Antonino, Marianna Di Maso, Nicola Muscatiello, Gastroenterology Section, Department of Medical Sciences, University of Foggia, 71100 Foggia, Italy
Author contributions: All the authors contributed to the article.
Correspondence to: Dr. Antonio Facciorusso, Gastroenterology Section, Department of Medical Sciences, University of Foggia, AOU Ospedali Riuniti, Viale Pinto, 1, 71100 Foggia, Italy. antonio.facciorusso@virgilio.it
Telephone: +39-881-732154 Fax: +39-881-733848
Received: May 2, 2014
Revised: June 30, 2014
Accepted: October 1, 2014
Published online: November 16, 2014
Processing time: 200 Days and 14.9 Hours
Revised: June 30, 2014
Accepted: October 1, 2014
Published online: November 16, 2014
Processing time: 200 Days and 14.9 Hours
Core Tip
Core tip: Endoscopic submucosal dissection (ESD) represents a promising approach to the therapy of Early Gastric Cancer. Preliminar studies showed better outcomes in terms of complete en bloc and histologic resection rate with respect to classical Endoscopic Mucosal Resection (EMR). Some concerns raise due to higher complication rate (particularly perforation) and longer operation times related to the complexity of the procedure. The current meta-analysis outline the superiority of ESD in obtaining higher radical resection rate and lower recurrence rates compared to EMR but confirms the aforementioned concerns on higher incidences of perforation and bleeding (in this case non significantly) after ESD.