Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Endosc. Jun 16, 2026; 18(6): 122027
Published online Jun 16, 2026. doi: 10.4253/wjge.v18.i6.122027
Published online Jun 16, 2026. doi: 10.4253/wjge.v18.i6.122027
Lower gastrointestinal bleeding attributed to xanthogranulomatous appendicitis: A case report
Bing-Xi Tang, Xiao-Dong Li, Department of Gastroenterology, Zibo Central Hospital, Zibo 255000, Shandong Province, China
Xin-Li Li, Laboratory Section, Zibo Central Hospital, Zibo 255000, Shandong Province, China
Author contributions: Tang BX performed the colonoscopy and drafted the manuscript; Li XL designed the research; Li XD helped collect the medical data; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Xin-Li Li, Associate Professor, Laboratory Section, Zibo Central Hospital, No. 54 Gongqingtuan Road, Zibo 255000, Shandong Province, China.
Received: April 8, 2026
Revised: April 27, 2026
Accepted: May 20, 2026
Published online: June 16, 2026
Processing time: 63 Days and 22.3 Hours
Revised: April 27, 2026
Accepted: May 20, 2026
Published online: June 16, 2026
Processing time: 63 Days and 22.3 Hours
Core Tip
Core Tip: Lower gastrointestinal bleeding (LGIB) has diverse etiologies, yet identifying the source remains challenging in approximately 10% of cases. Appendiceal bleeding is a rare condition that often necessitates repeated colonoscopy for diagnosis. Appendicitis is a recognized cause of LGIB, but bleeding due to xanthogranulomatous appendicitis (XGA) has not been reported in the literature. We present possibly the first case of XGA presenting with LGIB, which was diagnosed endoscopically and confirmed surgically.