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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Endosc. Mar 16, 2026; 18(3): 115257
Published online Mar 16, 2026. doi: 10.4253/wjge.v18.i3.115257
Giant rectal intramural hematoma following endoscopic submucosal dissection successfully treated with conservative therapy: A case report
Yan-Ling Xu, Man-Li Zhang, Hong-Jie Zhou, Pu-Jun Gao, Xiu-Na Zhang, Min Rao
Yan-Ling Xu, Pu-Jun Gao, Department of Hepatology, The First Hospital of Jilin University, Changchun 130000, Jilin Province, China
Man-Li Zhang, Hong-Jie Zhou, Xiu-Na Zhang, Min Rao, Department of Gastroenterology, Lequn Branch, The First Hospital of Jilin University, Changchun 130000, Jilin Province, China
Co-first authors: Yan-Ling Xu and Man-Li Zhang.
Author contributions: Xu YL and Zhang ML contributed equally to this work as co-first authors; Xu YL was the principal physician in charge of the patient’s management, collected the clinical data, and was the primary author of the manuscript; Zhang ML assisted in the endoscopic procedure, data collection, and literature review; Zhou HJ and Gao PJ participated in the patient’s clinical care and data analysis; Zhang XN contributed to the data interpretation and revision of the manuscript; Rao M supervised the entire clinical management, provided critical intellectual input, and is the corresponding author responsible for the manuscript. All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Min Rao, Department of Gastroenterology, Lequn Branch, The First Hospital of Jilin University, No. 3302 Jilin Road, Changchun 130000, Jilin Province, China. raomin@jlu.edu.cn
Received: October 15, 2025
Revised: December 9, 2025
Accepted: January 15, 2026
Published online: March 16, 2026
Processing time: 150 Days and 23.3 Hours
Core Tip

Core Tip: This report describes a case of delayed intramural hematoma occurring on the fourth day after endoscopic submucosal dissection of a rectal laterally spreading tumor. The intramural hematoma was successfully treated non-surgically, resulting in complete recovery. In contrast to previously reported fatal outcomes, this case provides valuable clinical evidence that careful non-surgical management can achieve excellent results, highlighting an important strategy for endoscopists to avoid unnecessary invasive interventions.