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Case Report
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2026; 18(2): 115745
Published online Feb 16, 2026. doi: 10.4253/wjge.v18.i2.115745
Huge esophagogastric submucosal hematoma associated with arterial malformations: A case report
Jia-Jia Wu, Dan Chen, Dong Liu, Ding-Fu Zhong
Jia-Jia Wu, Dan Chen, Dong Liu, Ding-Fu Zhong, Department of Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People’s Hospital, Jinhua 213000, Zhejiang Province, China
Co-first authors: Jia-Jia Wu and Dan Chen.
Author contributions: Wu JJ and Chen D contributed equally to this manuscript and are co-first authors; Wu JJ contributed to the original draft; Chen D and Zhong DF contributed to the conceptualization and validation; Liu D contributed to the review and editing; Zhong DF contributed to the supervision; Wu JJ and Zhong DF wrote the review and edited; Liu D and Zhong DF contributed to the visualization.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ding-Fu Zhong, Chief Physician, Department of Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People’s Hospital, No. 267 Danxi Road, Jinhua 213000, Zhejiang Province, China. 18757923011@sohu.com
Received: October 24, 2025
Revised: November 25, 2025
Accepted: December 23, 2025
Published online: February 16, 2026
Processing time: 103 Days and 12.8 Hours
Core Tip

Core Tip: Submucosal hematoma of the stomach or esophagus is rare and can result due to endoscopic therapy, coagulopathy, trauma, anticoagulation therapy, or repeated vomiting. The presence of both esophageal and gastric submucosal hematomas is rare. We present a 57-year-old male with huge gastric and esophageal submucosal hematomas. Endoscopy showed esophageal stenosis; computed tomography confirmed the diagnosis of gastric and esophageal submucosal hematomas associated with arterial malformations. The patient has a history of hypertension. The appearance of vascular malformations in the patient may be due to long-term hypertension causing endothelial damage in the blood vessels. Vascular embolization of the malformed arteries was performed first, followed by conservative treatment of the hematomas. The patient’s symptoms were relieved, and the hematomas were reduced.