Malignant gastric outlet obstruction: The emerging role of endoscopic ultrasound-guided gastroenterostomy

doi:10.4253/wjge.v17.i8.110301

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Aug 16, 2025 (publication date) through Aug 15, 2025

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Gastrointest Endosc. Aug 16, 2025; 17(8): 110301
Published online Aug 16, 2025. doi: 10.4253/wjge.v17.i8.110301

Malignant gastric outlet obstruction: The emerging role of endoscopic ultrasound-guided gastroenterostomy

Filippo Antonini, Giacomo Emanuele Maria Rizzo, Lorenzo Fuccio, Ilaria Tarantino

Filippo Antonini, Gastroenterology and Interventional Endoscopy Unit, C. e G. Mazzoni Hospital, Ascoli Piceno 63100, Marche, Italy

Giacomo Emanuele Maria Rizzo, Ilaria Tarantino, Gastroenterology and Endoscopy Unit, IRCCS-ISMETT (Mediterranean Institute for Transplantation and Highly Specialized Therapies), Palermo 90127, Sicilia, Italy

Lorenzo Fuccio, Department of Medical and Surgical Sciences, University of Bologna, Bologna 40138, Emilia-Romagna, Italy

Author contributions: Antonini F wrote the original draft and contributed to conceptualization and reviewing; Rizzo GEM and Fuccio L contributed to writing, reviewing and editing; Tarantino I participated in drafting the manuscript and supervised the manuscript preparation; all authors have read and approved the final version of the manuscript.

Conflict-of-interest statement: The authors declare no conflicts of interest.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Filippo Antonini, MD, Gastroenterology and Interventional Endoscopy Unit, C. e G. Mazzoni Hospital, Via Augusto Murri 1, Ascoli Piceno 63100, Marche, Italy. filippore@yahoo.it

Received: June 4, 2025
Revised: June 27, 2025
Accepted: July 25, 2025
Published online: August 16, 2025
Processing time: 72 Days and 10.7 Hours

Core Tip

Core Tip: Endoscopic ultrasound-guided gastroenterostomy is gaining clinical application in the palliative management of malignant gastric outlet obstruction. It provides superior long-term patency and lower reintervention rates compared to enteral stenting, while offering faster recovery and fewer complications than surgical gastrojejunostomy.