Systematic Reviews
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jul 16, 2025; 17(7): 108264
Published online Jul 16, 2025. doi: 10.4253/wjge.v17.i7.108264
Diagnostic yield of video capsule endoscopy vs simple balloon enteroscopy in small intestinal disorders: A systematic review
Eyad Gadour, Bogdan Miutescu, Hussein Hassan Okasha, Ana Maria Ghiuchici, Mohammed S AlQahtani
Eyad Gadour, Mohammed S AlQahtani, Multiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia
Eyad Gadour, Internal Medicine, Faculty of Medicine, Zamzam University College, Khartoum 11113, Sudan
Bogdan Miutescu, Ana Maria Ghiuchici, Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara 300041, Romania
Bogdan Miutescu, Advanced Regional Research Centre in Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, Timisoara 300041, Romania
Hussein Hassan Okasha, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kasr Al-Aini School of Medicine, Cairo University, Cairo 11562, Egypt
Ana Maria Ghiuchici, Advanced Regional Research Center in Gastroenterology and Hepatology, “Victor Babes” University of Medicine and Pharmacy, Timisoara 300041, Romania
Mohammed S AlQahtani, Department of Surgery, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia
Author contributions: Gadour E and AlQahtani MS contributed to conceptualization; Miutescu B, Ghiurchici AM and Okasha HH contributed to methodology; Miutescu B and Gadour E contributed to validation; Okasha HH, AlQahtani MS and Ghiurchici AM contributed to formal analysis, investigation and resources; Miutescu B and Okasha HH contributed to writing original draft preparation; Ghiurchici AM, Gadour E and AlQahtani MS contributed to writing, reviewing and editing; Miutescu B contributed to visualization; AlQahtani MS contributed to supervision; Gadour E contributed to project administration, data curation; All authors have read and agreed to the published version of the manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bogdan Miutescu, MD, PhD, Assistant Professor, Consultant, Department of Gastroenterology and Hepatology, Victor Babes University of Medicine and Pharmacy, "Victor Babes" Timisoara, Timisoara 300041, Romania. bmiutescu@yahoo.com
Received: April 10, 2025
Revised: April 21, 2025
Accepted: June 17, 2025
Published online: July 16, 2025
Processing time: 90 Days and 12.9 Hours
Core Tip

Core Tip: Video capsule endoscopy (VCE) and simple balloon enteroscopy (SBE) are complementary techniques for evaluating small intestinal disorders. VCE is preferred as an initial non-invasive diagnostic tool, while SBE excels in therapeutic interventions and histopathological confirmations. VCE shows superior performance in detecting vascular lesions, whereas SBE is more effective for ulcerative lesions and Crohn's disease. The choice between modalities depends on the suspected lesion type and need for intervention. Combining both techniques enhances diagnostic accuracy and patient management. Future research should focus on improving diagnostic concordance and refining interpretation of VCE findings to optimize the diagnostic pathway for small bowel disorders.