Current status of endoscopic treatment for esophageal diverticulum based on diverticular peroral endoscopic myotomy

doi:10.4253/wjge.v17.i6.106799

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Jun 16, 2025 (publication date) through Jun 11, 2025

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Jun 16, 2025; 17(6): 106799
Published online Jun 16, 2025. doi: 10.4253/wjge.v17.i6.106799

Current status of endoscopic treatment for esophageal diverticulum based on diverticular peroral endoscopic myotomy

Guo-Yao Sun, Yong Sun, Xue-Zhu Wang, Wen Jia, Jiao Liu, Zhuo Yang, Jiang-Ning Gu

Guo-Yao Sun, Yong Sun, Xue-Zhu Wang, Wen Jia, Jiao Liu, Zhuo Yang, Jiang-Ning Gu, Department of Endoscopy, General Hospital of Northern Theater Command, Shenyang 110000, Liaoning Province, China

Co-first authors: Guo-Yao Sun and Yong Sun.

Co-corresponding authors: Zhuo Yang and Jiang-Ning Gu.

Author contributions: Yang Z and Gu JN contributed to concept and design; Sun GY, Sun Y contributed to writing original draft; Gu JN, Yang Z, Sun GY and Sun Y contributed to review and editing the manuscript; Wang XZ contributed to statistical analysis and software; Jia W contributed to visualization and data curation; Liu J contributed to project administration and investigation; Yang Z and Gu JN contributed to validation and supervision; Sun GY and Sun Y have contributed equally to this work and are co-first authors; Yang Z and Gu JN are co-corresponding authors.

Supported by the Department of Science and Technology of Liaoning Province, No. 2024JH2/102600288.

Conflict-of-interest statement: The authors declare that they have no conflict of interest.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Zhuo Yang, Associate Chief Physician, Professor, Department of Endoscopy, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenhe District, Shenyang 110000, Liaoning Province, China. yangzhuocy@163.com

Received: March 9, 2025
Revised: April 9, 2025
Accepted: May 18, 2025
Published online: June 16, 2025
Processing time: 94 Days and 19 Hours

Core Tip

Core Tip: Since submucosal tunneling endoscopic septum division was introduced for the endoscopic treatment of Zenker’s diverticulum, it has been proven to offer superior safety and clinical success rates. The treatment of esophageal diverticulum based on Zenker’s peroral endoscopic myotomy and its various technical modifications is collectively referred to as diverticular peroral endoscopic myotomy; however, the nomenclature and abbreviations for these techniques have not yet been fully standardized. This review will summarize the characteristics of esophageal diverticulum and key aspects of the diverticular peroral endoscopic myotomy procedure.