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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2025; 17(5): 105158
Published online May 16, 2025. doi: 10.4253/wjge.v17.i5.105158
Efficacy and safety of endoscopic gastroplasty for treatment of obesity: An overview of comparative meta-analyses
Román Turró Arau, Jehad AlQamish, Nafeesa Mohammed, Maheeba Abdulla
Maheeba Abdulla, Jehad AlQamish, Department of Internal Medicine, Ibn Al Nafees Hospital, Manama 54533, Bahrain
Nafeesa Mohammed, Department of Intensive Care Unit, Salmaniya Medical Complex, Manama 5616, Bahrain
Román Turró Arau, Centro Medico Teknon, 08022, Barcelona, Spain
Author contributions: All authors contributed to the study conception and design; Material preparation, data collection, and analysis were performed by Abdulla M, Mohammed N, and AlQamish J; The first draft of the manuscript was written by Abdulla M; all authors commented on previous versions of the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Maheeba Abdulla, MD, Department of Internal Medicine, Ibn Al Nafees Hospital, PO Box 54533, Manama 54533, Bahrain. amaheeba@hotmail.com
Received: January 14, 2025
Revised: March 10, 2025
Accepted: April 22, 2025
Published online: May 16, 2025
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Core Tip

Core Tip: Endoscopic gastroplasty treatments were significantly better in reducing total body weight, excessive weight, and average weight among obese population. No significant difference between endoscopic transoral outlet reduction and full-thickness suturing plus argon plasma mucosal coagulation. Lack of comparative, long-term follow-up and randomized studies, reporting and selection bias, high level of heterogeneity were the major limitations in the currently available meta-analyses.