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Retrospective Study
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Nov 16, 2025; 17(11): 109909
Published online Nov 16, 2025. doi: 10.4253/wjge.v17.i11.109909
Endoscopic retrograde cholangiopancreatography in pediatric and adult populations: 17-year experience from Pakistan with trends, complications, and global comparison
Noval Zakaria, Muhammad U Tahseen, Talha S Niaz, Muhammad Asim, Asma Yaseen, Shanil Kadir, Sajida Qureshi, Shahriyar Ghazanfar, Aftab Leghari, Muhammad A Taj, Arif R Siddiqui, Abeer Altaf, Naseer Ahmed, Areeba Raza, Javeria Salman, Umer B Shoaib, Mehreen Siyal, Abdul K Durvesh, Saad K Niaz
Noval Zakaria, Muhammad U Tahseen, Muhammad Asim, Asma Yaseen, Shanil Kadir, Sajida Qureshi, Shahriyar Ghazanfar, Aftab Leghari, Muhammad A Taj, Arif R Siddiqui, Abeer Altaf, Naseer Ahmed, Areeba Raza, Javeria Salman, Umer B Shoaib, Mehreen Siyal, Abdul K Durvesh, Saad K Niaz, Department of Gastroenterology, Sindh Institute of Advanced Endoscopy and Gastroenterology, Karachi 75000, Sindh, Pakistan
Talha S Niaz, Department of Gastroenterology, Darent Valley Hospital, Dartford DA2 8DA, Kent, United Kingdom
Co-first authors: Noval Zakaria and Muhammad U Tahseen.
Author contributions: Zakaria N designed the report and supervised the project; Tahseen MU and Niaz TS collected the patients’ clinical data; Asim M and Yaseen A performed the data analysis; Kadir S and Qureshi S contributed to the literature review and interpretation of findings; Ghazanfar S and Laghari A contributed to data visualization and formatting; Taj MA and Siddiqui A revised the manuscript critically for important intellectual content; Altaf A and Ahmed N coordinated ethical approvals and institutional communication; Raza A and Salman J assisted in drafting the manuscript; Shoaib UB, Siyal M, Durvesh AK, and Niaz SK finalized the manuscript for submission. Zakaria N and Tahseen MU contributed equally to this manuscript and are co-first authors. All authors reviewed and approved the final version of the manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of the Dow University of Health Sciences (Approval No: IRB-2222/DUHS/EXEMPTION/2021/339).
Informed consent statement: As this was a retrospective study using anonymized patient data, informed consent was waived by the Institutional Review Board.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.
Corresponding author: Shanil Kadir, PhD, Assistant Professor, Consultant, FRCP, Department of Gastroenterology, Sindh Institute of Advanced Endoscopy and Gastroenterology, Heritage Building, Dr Ruth K.M. Pfau Civil Hospital, Karachi 75000, Sindh, Pakistan. shanildr@yahoo.com
Received: June 10, 2025
Revised: July 4, 2025
Accepted: October 10, 2025
Published online: November 16, 2025
Processing time: 160 Days and 3.8 Hours
Core Tip

Core Tip: We performed a retrospective analysis of 13215 endoscopic retrograde cholangiopancreatography (ERCP) procedures at a single tertiary care hospital in Karachi, Pakistan. We aimed to identify the quality, safety, and efficacy of ERCP in South Asia. The findings demonstrated the dependability of ERCP in a resource-constrained environment with excellent cannulation success rates (over 93%) and a low incidence of significant problems. The findings highlighted the critical need to increase ERCP access and specialized training throughout the region to improve outcomes for individuals with pancreatobiliary illnesses.

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