Ilhan E, Cengiz F. Endoscopic submucosal dissection, transanal endoscopic microsurgical submucosal dissection, and transanal minimally invasive surgery in rectal lesions. World J Gastrointest Endosc 2025; 17(10): 107792 [DOI: 10.4253/wjge.v17.i10.107792]
Corresponding Author of This Article
Enver Ilhan, Full Professor, Department of General Surgery, University of Health Sciences Turkey, Izmir Faculty of Medicine, Izmir City Hospital, Şevket İnce Mahallesi, 2148/11 Sokak No. 1/11, Turkey, İzmir 35040, Türkiye. enverhan60@gmail.com
Research Domain of This Article
Surgery
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Minireviews
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Oct 16, 2025 (publication date) through Oct 19, 2025
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Publication Name
World Journal of Gastrointestinal Endoscopy
ISSN
1948-5190
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Ilhan E, Cengiz F. Endoscopic submucosal dissection, transanal endoscopic microsurgical submucosal dissection, and transanal minimally invasive surgery in rectal lesions. World J Gastrointest Endosc 2025; 17(10): 107792 [DOI: 10.4253/wjge.v17.i10.107792]
World J Gastrointest Endosc. Oct 16, 2025; 17(10): 107792 Published online Oct 16, 2025. doi: 10.4253/wjge.v17.i10.107792
Endoscopic submucosal dissection, transanal endoscopic microsurgical submucosal dissection, and transanal minimally invasive surgery in rectal lesions
Enver Ilhan, Fevzi Cengiz
Enver Ilhan, Department of General Surgery, University of Health Sciences Turkey, Izmir Faculty of Medicine, Izmir City Hospital, İzmir 35040, Türkiye
Fevzi Cengiz, Department of General Surgery, Katip Celebi University Ataturk Training and Research Hospital, İzmir 35150, Türkiye
Author contributions: Ilhan E contributed by writing-reviewing and editing the manuscript; Cengiz F contributed by writing the manuscript and reviewing the literature; All authors read and approved the final version of the manuscript.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest related to this research/study/project. All authors have no personal or financial relationships that could influence the manuscript.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Enver Ilhan, Full Professor, Department of General Surgery, University of Health Sciences Turkey, Izmir Faculty of Medicine, Izmir City Hospital, Şevket İnce Mahallesi, 2148/11 Sokak No. 1/11, Turkey, İzmir 35040, Türkiye. enverhan60@gmail.com
Received: April 1, 2025 Revised: May 30, 2025 Accepted: August 19, 2025 Published online: October 16, 2025 Processing time: 201 Days and 11.5 Hours
Core Tip
Core Tip: Minimally invasive en bloc resection techniques have revolutionized the management of large rectal lesions, especially non-pedunculated polyps and early rectal cancers. This minireview compares three major approaches, namely, endoscopic submucosal dissection (ESD), transanal endoscopic microsurgical submucosal dissection (TEM-ESD), and transanal minimally invasive surgery (TAMIS), in terms of efficacy, safety, and technical feasibility. While ESD and TEM-ESD offer high en bloc resection rates with low recurrence, TAMIS is gaining popularity for its ergonomic advantages and ease of use. The minireview provides a critical perspective on indications, limitations, and future innovations, guiding clinicians in selecting the most appropriate technique based on lesion characteristics and institutional expertise.
