Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2024; 16(9): 526-532
Published online Sep 16, 2024. doi: 10.4253/wjge.v16.i9.526
Prevalence and resistance of Helicobacter pylori in a predominantly Hispanic population
Alireza Tabesh, Ricardo Alberto Antillon, Manvel Kondradzhyan, Ann Zera Tan
Alireza Tabesh, Manvel Kondradzhyan, Internal Medicine, Adventist Health White Memorial, Los Angeles, CA 90033, United States
Ricardo Alberto Antillon, Family Medicine, UCLA, Los Angeles, CA 90024, United States
Ann Zera Tan, Department of Pathology, Adventist Health White Memorial, Los Angeles, CA 90033, United States
Author contributions: Tabesh A, Kondradzhyan M, and Tan AZ designed the research study; Tabesh A enrolled patients, performed all endoscopies, and gathered data; Antillon RA was in charge of data analysis; Kondradzhyan M did preliminary research and presentations necessary to obtain funding and IRB; Tan AZ oversaw microbiology and pathology department and management of specimen; and all authors have read and approved the final manuscript.
Institutional review board statement: Institutional review board approval was obtained via WCG for the study, consent form and questionnaire as well as their Spanish translation effective September 1, 2017 (Approval No. 1177305).
Informed consent statement: An informed signed written consent was obtained from each patient in either English or Spanish, depending on the patient preference, prior to their enrollment.
Conflict-of-interest statement: None of the authors of this manuscript have any conflicts-of-interest that need to be disclosed.
Data sharing statement: All data, analytic methods, and study materials will be available upon request.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ricardo Alberto Antillon, MS, Researcher, Family Medicine, UCLA, 885 Tiverton Dr, Los Angeles, CA 90024, United States. rantillon@mednet.ucla.edu
Received: March 28, 2024
Revised: May 29, 2024
Accepted: July 30, 2024
Published online: September 16, 2024
Processing time: 167 Days and 3.9 Hours
Core Tip

Core Tip: Gastric biopsies obtained from patients with gastritis in a predominantly indigent immigrant community in Los Angeles were tested for Helicobacter pylori in order to better understand its prevalence and resistance. Immigrants from Mexico found to have a significantly higher risk of infection regardless of length of time in the United States. Infection is significantly higher in those who did not take a proton pump inhibitor. Clarithromycin and levofloxacin should be avoided as first line therapy in this region, particularly in patients of Latin American origin. Infection appears to be associated with low socioeconomic status and poor living conditions early in life.