Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2024; 16(9): 519-525
Published online Sep 16, 2024. doi: 10.4253/wjge.v16.i9.519
Can early precut reduce post-endoscopic retrograde cholangiopancreatography pancreatitis in patients with difficult bile duct cannulation?
Tomohiro Tanikawa, Keisuke Miyake, Mayuko Kawada, Katsunori Ishii, Takashi Fushimi, Noriyo Urata, Nozomu Wada, Ken Nishino, Mitsuhiko Suehiro, Miwa Kawanaka, Hidenori Shiraha, Ken Haruma, Hirofumi Kawamoto
Tomohiro Tanikawa, Keisuke Miyake, Mayuko Kawada, Katsunori Ishii, Takashi Fushimi, Noriyo Urata, Nozomu Wada, Ken Nishino, Mitsuhiko Suehiro, Miwa Kawanaka, Hidenori Shiraha, Ken Haruma, Hirofumi Kawamoto, Department of General Internal Medicine 2, Kawasaki Medical School, Okayama 7008505, Japan
Author contributions: Tanikawa T and Kawamoto H designed the study; Miyake K, Kawada M, and Ishii K performed the study; Urata N, Kawanaka M, and Tanikawa T analyzed the data; Tanikawa T, Nishino K, and Suehiro M drafted the manuscript; Fushimi T, Wada N, and Shiraha H critically revised the manuscript for important intellectual content; Kawamoto H and Haruma K supervised the study.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Kawasaki Medical School.
Informed consent statement: This research study is a retrospective study that does not discuss individual patients.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tomohiro Tanikawa, PhD, Assistant Professor, Doctor, Department of General Internal Medicine 2, Kawasaki Medical School, 2-6-1, Nakasange, Kita-ku, Okayama 7008505, Japan. t-tanikawa@med.kawasaki-m.ac.jp
Received: July 1, 2024
Revised: August 1, 2024
Accepted: August 12, 2024
Published online: September 16, 2024
Processing time: 72 Days and 23.9 Hours
Core Tip

Core Tip: Early needle-knife precut papillotomy (NKPP) may significantly reduce the incidence of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) in patients with difficult bile duct cannulation. Our single-center retrospective study found that early NKPP (EP) within 10 min of standard cannulation attempts led to a lower PEP rate compared to delayed NKPP (DP). When EP is not feasible, inserting a pancreatic stent after DP effectively prevents PEP, demonstrating a similar protective effect as EP. These findings suggest adopting EP or pancreatic stenting for delayed procedures to improve patient outcomes.