Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2024; 16(9): 509-518
Published online Sep 16, 2024. doi: 10.4253/wjge.v16.i9.509
Predictors of stricture after endoscopic submucosal dissection of the esophagus and steroids application
Qing-Xia Wang, Yuan Ding, Qi-Liu Qian, Yin-Nan Zhu, Rui-Hua Shi
Qing-Xia Wang, Yuan Ding, Qi-Liu Qian, Yin-Nan Zhu, Rui-Hua Shi, Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Medical School, Nanjing 210009, Jiangsu Province, China
Author contributions: Wang QX design the study and write the report; Ding Y, Qian QL and Zhu YN collect, analyze, and interpret the data; Shi RH provide guidance on thesis design; all authors agree to submit for publication.
Supported by Jiangsu Province Chinese Medicine Science and Technology Development Program, No. ZT202119.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: No benefits in any form have been received. All authors declare there are no conflicts of interest regarding the publication of this paper.
Data sharing statement: No data available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rui-Hua Shi, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Medical School, No. 87 Dingjiaqiao, Gulou District, Nanjing 210009, Jiangsu Province, China. ruihuashi@126.com
Received: June 21, 2024
Revised: August 21, 2024
Accepted: August 29, 2024
Published online: September 16, 2024
Processing time: 82 Days and 21.6 Hours
Core Tip

Core Tip: Steroid administration can help prevent post-esophageal endoscopic submucosal dissection (ESD) stricture. This study was clarified the risk factors of stricture even with steroid administration. Although steroids were administered to prevent esophageal strictures after ESD, the lesion circumference and submucosal injection of sodium hyaluronate remained independent predictors of esophageal stricture formation. Among them, submucosal injection of sodium hyaluronate was the first influential factor that may be a guide for clinical prevention.