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World J Gastrointest Endosc. Aug 16, 2024; 16(8): 451-461
Published online Aug 16, 2024. doi: 10.4253/wjge.v16.i8.451
Unveiling hidden outcomes in malignant gastric outlet obstruction research – insights from a "Pancreas 2000" review
Filipe Vilas-Boas, Giacomo Emanuele Maria Rizzo, Charles De Ponthaud, Stuart Robinson, Sebastien Gaujoux, Gabriele Capurso, Giuseppe Vanella, Bahadır Bozkırlı
Filipe Vilas-Boas, Department of Gastroenterology, São João University Hospital, Porto 4200, Portugal
Giacomo Emanuele Maria Rizzo, Endoscopy Service, Department of Diagnostic and Therapeutic Services, Scientific Institute for Research, Hospitalization and Healthcare - The Mediterranean Institute for Transplantation and Highly Specialized Therapies, Palermo 90127, Sicilia, Italy
Charles De Ponthaud, Sebastien Gaujoux, Department of Digestive, Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Pitié-Salpêtriere, Sorbonne Université, Paris 75013, Île-de-France, France
Stuart Robinson, Department of Hepatobiliary, Pancreatic and Transplant Surgery, Freeman Hospital, Newcastle NE7 7DN, Newcastle upon Tyne, United Kingdom
Gabriele Capurso, Giuseppe Vanella, Division of Pancreato-Biliary Endoscopy and Endosonography, Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano 20132, Italy
Bahadır Bozkırlı, Department of General Surgery, HPB-Unit, Acıbadem Maslak Hospital, Istanbul 34398, Türkiye
Author contributions: Vilas-Boas F and Bozkirli B contributed to literature search, compilation of relevant literature and drafting of the manuscript; Capurso G, Robinson S, and Gaujoux S contributed to article conception and critical revision of the manuscript; Vanella G, De Ponthaud C and Rizzo G contributed to compilation of relevant literature, critical review and revision of the manuscript; All the authors approved the final version of the article to be published.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Giuseppe Vanella, MD, PhD, Adjunct Professor, Doctor, Division of Pancreato-Biliary Endoscopy and Endosonography, Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, Milan 20132, Italy. vanella.giuseppe@hsr.it
Received: June 15, 2024
Revised: July 6, 2024
Accepted: July 16, 2024
Published online: August 16, 2024
Processing time: 47 Days and 9.6 Hours
Core Tip

Core Tip: Gastric outlet obstruction (GOO) is a common complication in pancreatobiliary malignancies, with growing research on its surgical and endoscopic management. However, current studies often overlook the patient's perspective and important clinical outcomes. This publication discusses the need to incorporate body mass composition, nutritional status, chemotherapy tolerance, and quality of life into future GOO research to provide a more comprehensive understanding of patient well-being and treatment effectiveness.