Retrospective Cohort Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Apr 16, 2023; 15(4): 285-296
Published online Apr 16, 2023. doi: 10.4253/wjge.v15.i4.285
Relationships of hospitalization outcomes and timing to endoscopy in non-variceal upper gastrointestinal bleeding: A nationwide analysis
Simcha Weissman, Muhammad Aziz, Ayrton I Bangolo, Dean Ehrlich, Arnold Forlemu, Anthony Willie, Manesh K Gangwani, Danish Waqar, Hannah Terefe, Amritpal Singh, Diego MC Gonzalez, Jayadev Sajja, Fatma L Emiroglu, Nicholas Dinko, Ahmed Mohamed, Mark A Fallorina, David Kosoy, Ankita Shenoy, Anvit Nanavati, Joseph D Feuerstein, James H Tabibian
Simcha Weissman, Ayrton I Bangolo, Anthony Willie, Danish Waqar, Hannah Terefe, Amritpal Singh, Diego MC Gonzalez, Jayadev Sajja, Fatma L Emiroglu, Nicholas Dinko, Ahmed Mohamed, Mark A Fallorina, David Kosoy, Ankita Shenoy, Anvit Nanavati, Department of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States
Muhammad Aziz, Manesh K Gangwani, Department of Gastroenterology, University of Toledo Medical Center, Toledo, OH 43614, United States
Dean Ehrlich, Division of Digestive Diseases, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, CA 90095, United States
Arnold Forlemu, Department of Internal Medicine, Creighton University School of Medicine, Phoenix, AZ 85012, United States
Joseph D Feuerstein, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States
James H Tabibian, Division of Gastroenterology, Department of Medicine, Olive View- University of California at Los Angeles Medical Center, Sylmar, CA 91342, United States
Author contributions: Weissman S, Aziz M, and Bangolo A searched the literature, wrote, and revised the manuscript; Ehrlich D, Forlemu A, Willie A, Gangwani MK, Waqar D, Terefe H, Singh A, Gonzalez DMC, Sajja J, Emiroglu FL, Dinko N, Mohamed A, Fallorina MA, Kosoy D, Shenoy A, and Nanavati A revised and edited the manuscript; Feuerstein JD and Tabibian JH approved the final version and are the article’s guarantors; All authors certify that they contributed sufficiently to the intellectual content and data analysis; Each author has reviewed the final version of the manuscript and approved it for publication.
Conflict-of-interest statement: All the authors have no potential conflict of interest to disclose.
Data sharing statement: The National Inpatient Sample is a publicly available dataset.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ayrton I Bangolo, MBBS, MD, Doctor, Department of Internal Medicine, Palisades Medical Center, 7600 River Road, North Bergen, NJ 07047, United States. ayrtonbangolo@yahoo.com
Received: December 16, 2022
Peer-review started: December 16, 2022
First decision: February 20, 2023
Revised: February 22, 2023
Accepted: March 15, 2023
Article in press: March 15, 2023
Published online: April 16, 2023
Processing time: 119 Days and 1.8 Hours
Core Tip

Core Tip: Patients are often admitted for nonvariceal upper gastrointestinal bleeding (NVUGIB). There is not enough data on the importance and timing of esophagogastroduodenoscopy (EGD) in those scenarios. We investigated a nationally representative database to identify independent predictors of outcomes in patients with NVUGIB, with a particular focus on EGD timing, anticoagulation (AC) status, and demographic features. We found that early EGD in NVUGIB is associated with lower mortality and decreased healthcare usage, irrespective of AC status.