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World J Gastrointest Endosc. Feb 16, 2023; 15(2): 32-43
Published online Feb 16, 2023. doi: 10.4253/wjge.v15.i2.32
Endoscopic fluorescent lymphography for gastric cancer
Calcedonio Calcara, Sila Cocciolillo, Ylenia Marten Canavesio, Vincenzo Adamo, Silvia Carenzi, Daria Ilenia Lucci, Alberto Premoli
Calcedonio Calcara, Silvia Carenzi, Daria Ilenia Lucci, Alberto Premoli, Digestive Endoscopy Unit, S. Andrea Hospital, Vercelli 13100, Italy
Sila Cocciolillo, Digestive Endoscopy Unit, Padre Pio Hospital, Vasto 66054, Italy
Ylenia Marten Canavesio, Postgraduate School of Gastroenterology, Genova University, Genova 16132, Italy
Vincenzo Adamo, General Surgery Unit, S. Andrea Hospital, Vercelli 13100, Italy
Author contributions: Calcara C and Cocciolillo S wrote the manuscript; Canavesio YM, Adamo V, Carenzi S, Lucci DI and Premoli A reviewed the literature; All authors have read and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Calcedonio Calcara, MD, Director, Digestive Endoscopy Unit, S. Andrea Hospital, Corso Mario Abbiate No. 21, Vercelli 13100, Italy. calcedonio.calcara@aslvc.piemonte.it
Received: September 20, 2022
Peer-review started: September 20, 2022
First decision: November 25, 2022
Revised: December 18, 2022
Accepted: February 7, 2023
Article in press: February 7, 2023
Published online: February 16, 2023
Processing time: 133 Days and 14.2 Hours
Core Tip

Core Tip: Endoscopic injection of indocyanine green (ICG) the day before surgery is a simple technique that could increase the number of lymph nodes recovered during lymphadenectomy for advanced gastric cancer. In addition, ICG-guided sentinel lymph node detection could reduce unnecessary extensive lymphadenectomy and the amount of gastric resection in early gastric cancer. However, further research is needed to confirm its usefulness in both scenarios. Currently, D1/D2 Lymphadenectomy remains the standard of care for gastric cancer with suspected metastasis. Our review explores this topic in depth and provides practical information for the endoscopic use of ICG.