Kosumi K, Mima K, Kanemitsu K, Tajiri T, Takematsu T, Sakamoto Y, Inoue M, Miyamoto Y, Mizumoto T, Kubota T, Miyanari N, Baba H. Self-expanding metal stent placement and pathological alterations among obstructive colorectal cancer cases. World J Gastrointest Endosc 2022; 14(11): 704-717 [PMID: 36438885 DOI: 10.4253/wjge.v14.i11.704]
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Keisuke Kosumi, Department of Gastroenterological Surgery, Kumamoto University, Kuma- moto 860-8556, Japan
Kosuke Mima, Yuki Sakamoto, Mitsuhiro Inoue, Takao Mizumoto, Tatsuo Kubota, Nobutomo Miyanari, Department of Surgery, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan
Kosuke Kanemitsu, Takuya Tajiri, Toru Takematsu, Yuji Miyamoto, Hideo Baba, Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Honjo 860-8556, Kumamoto, Japan
Author contributions: Kosumi K, Mima K, Miyanari N and Baba H participated in study conception and design; All authors participated in data acquisition; Kosumi K and Mima K performed the statistical analyses and analyzed the data; Miyanari N and Baba H supervised the work; Kosumi K, Mima K, Miyamoto Y, Miyanari N and Baba H were the major contributors to manuscript preparation; All authors contributed to the manuscript, critically revised it, and approved the final version.
Institutional review board statement: This study was approved by the Human Ethics Review Committee of the National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan, No. 1061.
Informed consent statement: The requirement for written informed consent was waived in view of the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The analysis used anonymous clinical data.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Received: September 2, 2022 Peer-review started: September 2, 2022 First decision: September 19, 2022 Revised: September 23, 2022 Accepted: October 25, 2022 Article in press: October 25, 2022 Published online: November 16, 2022 Processing time: 72 Days and 12.7 Hours
Core Tip
Core Tip: This study aimed to determine whether self-expanding metal stent (SEMS) placement is associated with molecular or pathological features of colorectal carcinoma tissues. As a result, SEMS placement was significantly associated with venous invasion (P < 0.01), but not with the other features examined, including tumor size, disease stage, mutation status, and lymphatic invasion. In both the univariable and multivariable models with adjustment for potential factors including tumor location, histological type, and American Joint Committee on Cancer-pT stage, SEMS placement was significantly associated with severe venous invasion (P < 0.01). For the outcome category of severe venous invasion, the multivariable odds ratio for SEMS placement relative to transanal tube placement was 19.4 (95% confidence interval: 5.24–96.2).
