Endoscopic retrograde cholangiopancreatography guided interventions in the management of pancreatic cancer

doi:10.4253/wjge.v12.i10.323

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Oct 16, 2020 (publication date) through Feb 26, 2026

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World Journal of Gastrointestinal Endoscopy

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World J Gastrointest Endosc. Oct 16, 2020; 12(10): 323-340
Published online Oct 16, 2020. doi: 10.4253/wjge.v12.i10.323

Endoscopic retrograde cholangiopancreatography guided interventions in the management of pancreatic cancer

Muhammad Nadeem Yousaf, Hamid Ehsan, Ahsan Wahab, Ahmad Muneeb, Fizah S Chaudhary, Richard Williams, Christopher J Haas

Muhammad Nadeem Yousaf, Hamid Ehsan, Fizah S Chaudhary, Richard Williams, Christopher J Haas, Department of Medicine, Medstar Union Memorial Hospital, Baltimore, MD 21218, United States

Muhammad Nadeem Yousaf, Fizah S Chaudhary, Richard Williams, Christopher J Haas, Department of Medicine, MedStar Good Samaritan Hospital, Baltimore, MD 21239, United States

Muhammad Nadeem Yousaf, Fizah S Chaudhary, Richard Williams, Christopher J Haas, Department of Medicine, Medstar Franklin Square Medical Center, Baltimore, MD 21237, United States

Muhammad Nadeem Yousaf, Fizah S Chaudhary, Richard Williams, Christopher J Haas, Department of Medicine, MedStar Harbor Hospital, Baltimore, MD 21225, United States

Ahsan Wahab, Department of Hospital Medicine, Baptist Medical Center South, Montgomery, AL 36116, United States

Ahmad Muneeb, Department of Medicine, Faisalabad Medical University, Faisalabald 38000, Punjab, Pakistan

Author contributions: Yousaf MN and Ehsan H were involved in manuscript writing and overalled data collection; Wahab A, Muneeb A and Chaudhary FS did the review of manuscript and data; Williams R and Haas CJ did the manuscript supervision, review, and revision.

Conflict-of-interest statement: The authors have no conflict-of-interests.

Corresponding author: Muhammad Nadeem Yousaf, MD, Doctor, Department of Medicine, Medstar Union Memorial Hospital, 201 E University Pkwy, Baltimore, MD 21218, United States. nadeem.yousaf200@gmail.com

Received: June 16, 2020
Peer-review started: June 16, 2020
First decision: July 21, 2020
Revised: July 23, 2020
Accepted: September 22, 2020
Article in press: September 22, 2020
Published online: October 16, 2020
Processing time: 119 Days and 10.6 Hours

Core Tip

Core Tip: Endoscopic retrograde cholangiopancreatography (ERCP)-guided interventions have an important role in the diagnosis, treatment, and palliation of pancreatic cancer. ERCP-guided biliary tissue sampling assists in diagnosing pancreatic cancer and permit therapeutic interventions during the same procedure (if needed). Advanced pancreatic cancers may result in biliary or gastric outlet obstruction. ERCP-guided deployment of either biliary or enteral stents provides effective palliation and improves the quality of life. The selection of biliary stent subtype depends on multiple factors including life expectancy, risk of complications, cost, and the need for ERCP-guided reinterventions. Self-expandable metal stents are preferred over plastic stents because of longer luminal patency, lower rates of stent dysfunction, and overall cost.