Observational Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Nov 16, 2018; 10(11): 340-347
Published online Nov 16, 2018. doi: 10.4253/wjge.v10.i11.340
Polysomnographic assessment of respiratory disturbance during deep propofol sedation for endoscopic submucosal dissection of gastric tumors
Ryuma Urahama, Masaya Uesato, Mizuho Aikawa, Yukiko Yamaguchi, Koichi Hayano, Tomoaki Matsumura, Makoto Arai, Reiko Kunii, Shiroh Isono, Hisahiro Matsubara
Ryuma Urahama, Masaya Uesato, Mizuho Aikawa, Yukiko Yamaguchi, Koichi Hayano, Hisahiro Matsubara, Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan
Tomoaki Matsumura, Department of Gastroenterology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan
Makoto Arai, Department of Medical Oncology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan
Reiko Kunii, Staff of Clinical Laboratory, Chiba University Hospital, Chiba 260-8677, Japan
Shiroh Isono, Department of Anesthesiology, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan
Author contributions: Uesato M contributed to study conception; Urahama R and Uesato M contributed to study design and writing of article; Urahama R, Uesato M, Aikawa M, Yamaguchi Y, Hayano K, Matsumura T, Arai M contributed to diagnosis and treatment; Urahama R and Kunii R contributed to data acquisition; Urahama R, Uesato M and Isono S contributed to data analysis and interpretation; all authors discussed the results on article and contributed to final approval.
Supported by a grant received from Japan Society for the Promotion of Science, NO. 15K09056.
Institutional review board statement: This study was approved by the institutional Ethics Committee (#1902-2014, Graduate School of Medicine, Chiba University, Chiba, Japan).
Informed consent statement: The patients involved in this study gave his written informed consent authorizing use and disclosure of his protected health information.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Data sharing statement: No additional data are available.
STROBE statement: The guidelines of the STROBE statement have been adopted.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Masaya Uesato, MD, PhD, Assistant Professor, Department of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8670, Japan. uesato@faculty.chiba-u.jp
Telephone: +81-43-226-2110 Fax: +81-43-226-2113
Received: July 5, 2018
Peer-review started: July 5, 2018
First decision: July 19, 2018
Revised: August 21, 2018
Accepted: October 8, 2018
Article in press: October 9, 2018
Published online: November 16, 2018
Processing time: 134 Days and 14.9 Hours
Core Tip

Core tip: Our aim was to demonstrate respiratory disturbances using polysomnography (PSG) during propofol sedation for gastric endoscopic submucosal dissection. Among the ten patients, 207 respiratory disturbances were identified by PSG. Apnea hypopnea index (AHI), defined as the number of apnea and hypopnea per hour, detected by PSG was significantly greater than that detected by pulse oximeter. Obstructive AHI was significantly greater than central AHI. The 25 instances of respiratory disturbances with hypoxemia were detected on an average of 107.4 s before they were detected by pulse oximetry. PSG would be useful for monitoring respiratory conditions with better detectability of AHI.