Published online Sep 25, 2015. doi: 10.4253/wjge.v7.i13.1088
Peer-review started: April 24, 2015
First decision: June 2, 2015
Revised: June 17, 2015
Accepted: August 30, 2015
Article in press: September 7, 2015
Published online: September 25, 2015
Processing time: 153 Days and 17.7 Hours
Upper non-variceal gastrointestinal bleeding is a condition that requires immediate medical intervention and has a high associated mortality rate (exceeding 10%). The vast majority of upper gastrointestinal bleeding cases are due to peptic ulcers. Helicobacter pylori infection, non-steroidal anti-inflammatory drugs and aspirin are the main risk factors for peptic ulcer disease. Endoscopic therapy has generally been recommended as the first-line treatment for upper gastrointestinal bleeding as it has been shown to reduce recurrent bleeding, the need for surgery and mortality. Early endoscopy (within 24 h of hospital admission) has a greater impact than delayed endoscopy on the length of hospital stay and requirement for blood transfusion. This paper aims to review and compare the efficacy of the types of endoscopic hemostasis most commonly used to control non-variceal gastrointestinal bleeding by pooling data from the literature.
Core tip: Review and comparison the efficacy of the most commonly used types of endoscopic hemostasis for the control of non-variceal gastrointestinal bleeding in clinical practice by pooling data from the literature.