Published online Jan 16, 2015. doi: 10.4253/wjge.v7.i1.73
Peer-review started: August 13, 2014
First decision: September 16, 2014
Revised: October 17, 2014
Accepted: October 31, 2014
Article in press: November 3, 2014
Published online: January 16, 2015
Processing time: 156 Days and 17.4 Hours
Russell bodies are eosinophilic intracytoplasmic globules which are likely the result of disturbed secretion of immunoglobulins that accumulate within the plasma cell. Russell body collections have been identified within the stomach, known as Russell body gastritis. Similar lesions within the duodenum are referred to as Russell body duodenitis, which is rare. Several Russell body gastritis case reports are associated with Helicobacter pylori. However, the etiology of Russell body duodenitis remains unclear. Here we report the first case of Russell body duodenitis with immunoglobulin light chain restriction in a background of peptic duodenitis.
Core tip: Russell body duodenitis is rare and the etiology is unclear. We report a case of Russell body duodenitis with immunoglobulin light chain restriction in a background of peptic duodenitis.