Review
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jan 16, 2015; 7(1): 13-36
Published online Jan 16, 2015. doi: 10.4253/wjge.v7.i1.13
Small bowel capsule endoscopy: Where are we after almost 15 years of use?
Cedric Van de Bruaene, Danny De Looze, Pieter Hindryckx
Cedric Van de Bruaene, Danny De Looze, Pieter Hindryckx, Department of Gastro-enterology, University Hospital Ghent, 9000 Ghent, Belgium
Author contributions: Van de Bruaene C, De Looze D and Hindryckx P analyzed data; Van de Bruaene C and Hindryckx P wrote the paper; Van de Bruaene C, De Looze D and Hindryckx P revised the paper.
Conflict-of-interest: The authors declare that they have no competing interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Pieter Hindryckx, MD, Department of Gastro-enterology, University Hospital Ghent, de pintelaan 185, 1K12, 9000 Ghent, Belgium. hindryckx@ugent.be
Telephone: +32-9-3322371 Fax: +32-9-2404984
Received: August 29, 2014
Peer-review started: August 29, 2014
First decision: September 30, 2014
Revised: October 16, 2014
Accepted: December 3, 2014
Article in press: December 10, 2014
Published online: January 16, 2015
Processing time: 139 Days and 10.3 Hours
Abstract

The development of capsule endoscopy (CE) in 2001 has given gastroenterologists the opportunity to investigate the small bowel in a non-invasive way. CE is most commonly performed for obscure gastrointestinal bleeding, but other indications include diagnosis or follow-up of Crohn’s disease, suspicion of a small bowel tumor, diagnosis and surveillance of hereditary polyposis syndromes, Nonsteroidal anti-inflammatory drug-induced small bowel lesions and celiac disease. Almost fifteen years have passed since the release of the small bowel capsule. The purpose of this review is to offer the reader a brief but complete overview on small bowel CE anno 2014, including the technical and procedural aspects, the possible complications and the most important indications. We will end with some future perspectives of CE.

Keywords: Capsule endoscopy; Small bowel; Preparation; Procedure; Technology; Complications; Features; Enhancements; Indications; Future

Core tip: This review covers all the relevant aspects of small bowel capsule endoscopy anno 2014. The current techniques, procedures, analyses, indications and future perspectives are discussed thoroughly. Easy-to-use flowcharts are provided to help the readers in their decision-making when confronted with small bowel pathology.