Case Report
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World J Gastrointest Endosc. Oct 16, 2013; 5(10): 514-518
Published online Oct 16, 2013. doi: 10.4253/wjge.v5.i10.514
Duodenal subepithelial hyperechoic lesions of the third layer: Not always a lipoma
Pedro C Figueiredo, Pedro Pinto-Marques, Evelina Mendonça, Pedro Oliveira, Maria Brito, David Serra
Pedro C Figueiredo, Pedro Pinto-Marques, Gastroenterology Department, Hospital Garcia de Orta, Avenida Torrado da Silva, 2801-951 Almada, Portugal
Evelina Mendonça, Pedro Oliveira, Pathology Department, Hospital da Luz, Avenida Lusíada nº100, 1500-650 Lisboa, Portugal
Maria Brito, Pathology Department, Hospital Garcia de Orta, Avenida Torrado da Silva, 2801-951 Almada, Portugal
David Serra, Gastroenterology Department, Hospital da Luz, Avenida Lusíada nº100, 1500-650 Lisboa, Portugal
Author contributions: Figueiredo PC and Pinto-Marques P performed the echoendoscopic examinations; Mendonça E, Oliveira P and Brito M performed, reviewed the pathology examinations; Serra D performed the endoscopic therapeutic procedures; Figueiredo PC and Pinto-Marques P organized the report; Figueiredo PC wrote the paper; all authors read and approved the final manuscript.
Correspondence to: Pedro C Figueiredo, MD, Gastroenterology Department, Hospital Garcia de Orta, Avenida Torrado da Silva, Pragal, 2801-951 Almada, Portugal. pedro.c.figueiredo@hotmail.com
Telephone: +351-212-940294 Fax: +351-212-957004
Received: June 11, 2013
Revised: August 28, 2013
Accepted: September 3, 2013
Published online: October 16, 2013
Processing time: 126 Days and 16.5 Hours
Abstract

Endoscopic ultrasonography is the most accurate procedure for the evaluation of subepithelial lesions. The finding of a homogeneous, hyperechoic, well-delimited lesion, originating from the third layer of the gastrointestinal tract (submucosa) suggests a benign tumor, generally lipoma. As other differential diagnoses have not been reported, echoendoscopists might not pursue a definitive pathological diagnosis or follow-up the patient. This case series aims to broaden the spectrum of differential diagnosis for duodenal hyperechoic third layer subepithelial lesions by providing four different and relevant pathologies with this echoendoscopic pattern.

Keywords: Endoscopic ultrasonography; Endoscopic ultrasound-guided fine needle aspiration; Duodenum; Subepithelial tumor; Lipoma

Core tip: This case series reports four different and relevant pathologies with an echoendoscopic pattern usually suggestive of lipoma.