Non-invasive monitoring of inflammatory bowel disease using intestinal ultrasound

doi:10.4253/wjge.v17.i3.97016

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 3

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (2845)

All Articles published online

The chart showing PDF series, HTML series, Tables (1-1) series.

Item

Count

PDF

HTML

1342

Tables (1-1)

340

Sum=1770

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

201

Download

756

Sum=957

Mar 16, 2025 (publication date) through Feb 27, 2026

Times Cited of This Article

Times Cited (2)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Endoscopy

ISSN

1948-5190

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

World J Gastrointest Endosc. Mar 16, 2025; 17(3): 97016
Published online Mar 16, 2025. doi: 10.4253/wjge.v17.i3.97016

Non-invasive monitoring of inflammatory bowel disease using intestinal ultrasound

Hakima Abid, Hajar Cherkaoui, Fatima Benahsine, Asmae Lamine, Maria Lahlali, Ismail Chaouche, Fatima Bartal, Nada Lahmidani, Amine Elmekkaoui, Dafr Allah Benajah, Mohammed Abkari, Sidi Adil Ibrahimi, Karima Elghazi, Mustapha Maaroufi, Mounia Elyousfi, Faculty of Medicine, Pharmacy and Dental Medicine of Fez, University of Sidi Mohammed Benabdellah, Laboratory of Human Pathology, Biomedicine and Environment of The Faculty of Medicine, Pharmacy and Dental Medicine of Fez, Fez 30000, Morocco

Hakima Abid, Hajar Cherkaoui, Fatima Benahsine, Asmae Lamine, Maria Lahlali, Nada Lahmidani, Amine Elmekkaoui, Dafr Allah Benajah, Mohammed Abkari, Sidi Adil Ibrahimi, Mounia Elyousfi, Department of Gastroenterology, University Hospital Hassan II, Fez 30000, Morocco

Ismail Chaouche, Mustapha Maaroufi, Department of Radiology, University Hospital Hassan II, Fez 30000, Morocco

Fatima Bartal, Karima Elghazi, Department of Epidemiology, University Hospital Hassan II, Fez 30000, Morocco

Co-first authors: Hakima Abid and Hajar Cherkaoui.

Author contributions: Abid H performed intestinal ultrasound; Cherkaoui H designed the study and wrote the manuscript; Cherkaoui H, Benahsine F, Lamine A, Lahlali M, Lahmidani N, Elmekkaoui A, Benajah DA, Abkari M, Ibrahimi SA, and Elyousfi M contributed to patient outreach; Benahsine F helped with study design; Abid H and Elyousfi M contributed to the manuscript correction; Chaouche I and Maaroufi M provided radiological images; Bartal F and Elghazi K participated in the statistical analysis.

Institutional review board statement: The local ethics committee of the Fez University Hospital has given its consent to conduct this study.

Clinical trial registration statement: The study was registered at the Ethics Department in the University Hospital Hassan II as a prospective non interventional study.

Informed consent statement: All patients presented their informed consent before conducting this study.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.

Data sharing statement: We agree to sharing the data gathered from this study.

Corresponding author: Hajar Cherkaoui, MD, Department of Gastroenterology, University Hospital Hassan II, 3 Sidi Hrazem Street, Fes 30000, Morocco. hajar.cherkaouitangi@gmail.com

Received: May 20, 2024
Revised: August 26, 2024
Accepted: December 2, 2024
Published online: March 16, 2025
Processing time: 297 Days and 17.2 Hours

Abstract

BACKGROUND

Intestinal ultrasound (IUS) is a safe and effective way for the diagnosis and surveillance of patients with inflammatory bowel disease (IBD). It allows a noninvasive and reproducible follow-up for patients with IBD.

AIM

To compare the outcomes of colonoscopy and IUS in diagnosing and monitoring patients with IBD.

METHODS

A prospective study was conducted over a three-year period (January 2021 to April 2024) comparing endoscopic and IUS findings. A total of 101 patients were included in the study (68 with Crohn’s disease and 33 with ulcerative colitis). All patients underwent both IUS and colonoscopy within a 10-day period.

RESULTS

The study found a strong correlation between bowel thickening on IUS and inflammatory activity (P = 0.004), IUS remission and endoscopic remission (P = 0.03), IUS and endoscopic location (P = 0.04), as well as IUS and computed tomography scan findings for collection diagnosis (P < 0.01).

CONCLUSION

The study’s findings demonstrated excellent results for using IUS in the diagnosis and follow-up of IBD patients.

Keywords: Inflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Intestinal ultrasound; Endoscopy

Core Tip: This is the first single-blind prospective study conducted to compare the results of ultrasound and colonoscopy. Our goal is to present an objective comparison between intestinal ultrasound (IUS) and colonoscopy. All the patients with inflammatory bowel disease (Crohn’s or ulcerative colitis) were contacted by the same investigator (Dr. Hajar Cherkaoui) in a delay of 10 days of colonoscopies. The operator (Dr. Hakima Abid) did not know the results of colonoscopies while performing the IUS. This ensured objective, unbiased evaluation of IUS in the diagnosis and follow-up of inflammatory bowel disease patients.