Chen JL, Zhi HX, Pan JY, Chen ZH, Huang JL, Yao J. Hyperbaric oxygen therapy in the treatment of severe gastric laceration with active bleeding: A case report. World J Gastrointest Endosc 2025; 17(1): 100904 [DOI: 10.4253/wjge.v17.i1.100904]
Corresponding Author of This Article
Jun Yao, MD, PhD, Professor, Department of Gastroenterology, Shenzhen People’s Hospital (Jinan University of Second Clinical Medical Sciences), No. 1017 East Gate Road, Shenzhen 518020, Guangdong Province, China. yao.jun@szhospital.com
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Jan 16, 2025; 17(1): 100904 Published online Jan 16, 2025. doi: 10.4253/wjge.v17.i1.100904
Hyperbaric oxygen therapy in the treatment of severe gastric laceration with active bleeding: A case report
Jie-Li Chen, Hui-Xin Zhi, Jun-Yu Pan, Ze-Han Chen, Jia-Lan Huang, Jun Yao
Jie-Li Chen, Hui-Xin Zhi, Jun-Yu Pan, Ze-Han Chen, Jia-Lan Huang, Jun Yao, Department of Gastroenterology, Shenzhen People’s Hospital (Jinan University of Second Clinical Medical Sciences), Shenzhen 518020, Guangdong Province, China
Author contributions: Chen JL and Zhi HX drafted the manuscript; Yao J revised the manuscript; Pan JY and Chen ZH acquired the data and figures; Huang JL managed the patient and provided the case; and all authors had access and approved the last version of the manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Yao, MD, PhD, Professor, Department of Gastroenterology, Shenzhen People’s Hospital (Jinan University of Second Clinical Medical Sciences), No. 1017 East Gate Road, Shenzhen 518020, Guangdong Province, China. yao.jun@szhospital.com
Received: August 30, 2024 Revised: November 6, 2024 Accepted: December 12, 2024 Published online: January 16, 2025 Processing time: 139 Days and 15.7 Hours
Abstract
BACKGROUND
Endoscopic therapy is the primary approach for treating Mallory-Weiss syndrome, particularly under conditions of mucosal protection and gastric acid suppression. However, for a subset of patients who cannot undergo endoscopic intervention or for whom such treatment proves ineffective, alternative measures like arterial embolization or surgical intervention may be required. While hyperbaric oxygen therapy (HBOT) has been applied across a range of medical conditions, its application in managing hemorrhage due to gastric tears remains undocumented.
CASE SUMMARY
A 52-year-old patient was admitted with symptoms of hematemesis and melena, and an endoscopy revealed a gastric fundus tear approximately 4 cm × 5 cm in size. The lesion was considered unsuitable for endoscopic repair by the attending endoscopist. Despite conservative measures, including fasting and acid suppression, the patient experienced persistent bleeding and a substantial decrease in hemoglobin levels relative to admission values. Following a multidisciplinary consultation, HBOT was initiated, resulting in the cessation of bleeding and rapid wound healing.
CONCLUSION
For patients with gastric tears presenting with active hemorrhage, HBOT might offer an effective alternative when conventional endoscopic therapies are not viable or have been unsuccessful.
Core Tip: This case highlights the rapid healing of a gastric laceration using hyperbaric oxygen therapy, an approach not previously reported for treating gastric mucosal tears. Our findings suggest that hyperbaric oxygen therapy can be a viable treatment option for managing severe gastric lacerations with active bleeding, especially in cases where conservative or endoscopic therapies have failed and surgical intervention is not indicated.
