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World J Gastrointest Endosc. Jul 16, 2024; 16(7): 376-384
Published online Jul 16, 2024. doi: 10.4253/wjge.v16.i7.376
Advancements in endoscopic hemostasis for non-variceal upper gastrointestinal bleeding
Xue Jing Li, Brian M Fung
Xue Jing Li, Department of Gastroenterology and Hepatology, Banner-University Medical Center Phoenix, Phoenix, AZ 85006, United States
Brian M Fung, Department of Gastroenterology, Arizona Digestive Health, Mesa, AZ 85210, United States
Author contributions: Li XJ drafted the manuscript and prepared figures and tables; Fung BM designed the manuscript outline, prepared figures, and critically reviewed the manuscript. All authors provided critical input and approved the final version of the manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial See: Https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Brian M Fung, MD, Doctor, Department of Gastroenterology, Arizona Digestive Health, 603 W Baseline Rd, Ste 200, Mesa, AZ 85210, United States. brianfung@outlook.com
Received: March 27, 2024
Revised: June 6, 2024
Accepted: June 26, 2024
Published online: July 16, 2024
Processing time: 103 Days and 3.7 Hours
Abstract

Non-variceal upper gastrointestinal (GI) bleeding is a significant cause of morbidity and mortality. Traditionally, through-the-scope (TTS) clips, thermal therapy, and injection therapies are used to treat GI bleeding. In this review, we provide an overview of novel endoscopic treatments that can be used to achieve hemostasis. Specifically, we discuss the efficacy and applicability of over-the-scope clips, hemostatic agents, TTS doppler ultrasound, and endoscopic ultrasound, each of which offer an effective method of reducing rates of GI rebleeding.

Keywords: Doppler probe; Endoscopic ultrasound; Endoscopy techniques; Gastrointestinal bleeding; Hemospray; Hemostasis; Hemostatic agents; Over-the-scope clips; Ovesco

Core Tip: Non-variceal upper gastrointestinal bleeding is a significant cause of morbidity and mortality. In this review, we provide an overview of novel endoscopic treatments that can be used to achieve hemostasis. Specifically, we discuss the efficacy and applicability of over-the-scope clips, hemostatic agents, and adjunctive tools such as through-the-scope doppler ultrasound and endoscopic ultrasound.