Fiori E, Lamazza A, Crocetti D, Sterpetti AV. Editorial article to: Animal experimental study on magnetic anchor technique-assisted endoscopic submucosal dissection of early gastric cancer. World J Gastrointest Endosc 2024; 16(2): 51-54 [PMID: 38464819 DOI: 10.4253/wjge.v16.i2.51]
Corresponding Author of This Article
Enrico Fiori, MD, Chief Doctor, Director, Full Professor, Surgeon, Surgical Oncologist, Department of Surgery, Sapienza University of Rome, Policlinico “Umberto I”, Viale del Policlinico 155, Rome 00161, Italy. enrico.fiori@uniroma1.it
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Feb 16, 2024; 16(2): 51-54 Published online Feb 16, 2024. doi: 10.4253/wjge.v16.i2.51
Editorial article to: Animal experimental study on magnetic anchor technique-assisted endoscopic submucosal dissection of early gastric cancer
Enrico Fiori, Antonietta Lamazza, Daniele Crocetti, Antonio V Sterpetti
Enrico Fiori, Daniele Crocetti, Antonio V Sterpetti, Department of Surgery, Sapienza University of Rome, Rome 00161, Italy
Antonietta Lamazza, Department of Surgery, University of Rome La Sapienza, Rome 00161, Italy
Author contributions: Fiori E, Lamazza A, Crocetti D, and Sterpetti AV contributed to this paper; Fiori E designed the overall concept and outline of the manuscript; Lamazza A and Crocetti D contributed to the discussion and design of the manuscript; Sterpetti AV contributed to the writing, editing the manuscript, and review of literature.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Enrico Fiori, MD, Chief Doctor, Director, Full Professor, Surgeon, Surgical Oncologist, Department of Surgery, Sapienza University of Rome, Policlinico “Umberto I”, Viale del Policlinico 155, Rome 00161, Italy. enrico.fiori@uniroma1.it
Received: November 13, 2023 Peer-review started: November 13, 2023 First decision: December 7, 2023 Revised: December 7, 2023 Accepted: January 11, 2024 Article in press: January 11, 2024 Published online: February 16, 2024 Processing time: 78 Days and 19.9 Hours
Abstract
In this editorial we comment on the article published in the recent issue of the World Journal of Gastrointestinal Endoscopy 2023; 15 (11): 634-680. Gastric cancer (GC) remains the fifth most common malignancy and the fourth leading cause of cancer-related death worldwide. The overall prevalence of GC has declined, although that of proximal GC has increased over time. Thus, a significant proportion of GC cases and deaths can be avoided if preventive interventions are taken. Early GC (EGC) is defined as GC confined to the mucosa or submucosa. Endoscopic resection is considered the most appropriate treatment for precancerous gastrointestinal lesions improving patient quality of life, with reduced rates of complications, shorter hospitalization period, and lower costs when compared to surgical resection. Endoscopic mucosal resection (EMR) and endoscopic sub-mucosal dissection (ESD) are representative endoscopic treatments for EGC and precancerous gastric lesions. Standard EMR implies injection of a saline solution into the sub-mucosal space, followed by excision of the lesion using a snare. Complete resection rates vary depending on the size and severity of the lesion. When using conventional EMR methods for lesions less than 1 cm in size, the complete resection rate is approximately 60%, whereas for lesions larger than 2 cm, the complete resection rate is low (20%-30%). ESD can be used to remove tumors exceeding 2 cm in diameter and lesions associated with ulcers or submucosal fibrosis. Compared with EMR, ESD has higher en bloc resection rates (90.2% vs 51.7%), higher complete resection rates (82.1 vs 42.2%), and lower recurrence rates (0.65% vs 6.05%). Thus, innovative techniques have been introduced.
Core Tip: Endoscopic resection (ER) is considered the most appropriate treatment for precancerous gastrointestinal lesions improving patient quality of life, with reduced rates of complications, shorter hospitalization period, and lower costs when compared to surgical resection. Complete ER rates and recurrence rates after procedure vary depending on the size and severity of the lesion. Innovative techniques could improve endoscopic rate and clinical outcomes.
