• Humans
• Endosonography/methods
• Male
• Female
• Aged
• Middle Aged
• Magnetic Resonance Imaging/methods
• Tomography, X-Ray Computed/methods
• Pancreatic Neoplasms/diagnostic imaging
• Pancreatic Neoplasms/pathology
• Pancreatic Intraductal Neoplasms/diagnostic imaging
• Pancreatic Intraductal Neoplasms/pathology
• ROC Curve
• Carcinoma, Pancreatic Ductal/diagnostic imaging
• Carcinoma, Pancreatic Ductal/pathology
• Carcinoma, Pancreatic Ductal/diagnosis
• Adenocarcinoma, Mucinous/diagnostic imaging
• Adenocarcinoma, Mucinous/pathology
• Aged, 80 and over
• Retrospective Studies
• Adult
• Reproducibility of Results

• Abbreviated protocol
• Guidelines
• Intraductal papillary mucinous neoplasm
• Magnetic resonance imaging
• Surveillance

• Humans
• Pancreatic Intraductal Neoplasms
• Pancreatic Neoplasms
• Carcinoma, Pancreatic Ductal
• Magnetic Resonance Imaging
• Retrospective Studies

• IPMN
• Intraductal papillary mucinous neoplasms
• Pancreas
• Pancreatectomy
• Pancreatic cysts

• Diagnosis
• Early Detection
• Pancreas
• Pancreatic Cancer
• Pancreatic Neoplasm

• Humans
• Retrospective Studies
• Cystadenoma, Serous/diagnosis
• Prospective Studies
• Pancreatic Neoplasms/diagnosis
• Pancreatic Neoplasms/genetics
• Pancreatic Neoplasms/surgery
• Pancreatic Cyst/diagnosis
• Pancreatic Cyst/genetics
• Pancreatic Cyst/therapy
• High-Throughput Nucleotide Sequencing
• Endoscopic Ultrasound-Guided Fine Needle Aspiration
• Genomics
• Mitogen-Activated Protein Kinases/genetics

• R37 CA263622 NCI NIH HHS
• U01 CA200466 NCI NIH HHS
• P30 DK120531 NIDDK NIH HHS
• P30 CA015083 NCI NIH HHS
• P50 CA062924 NCI NIH HHS
• P30 CA006973 NCI NIH HHS

• Carcinoembryonic antigen
• Mucinous cyst
• Non-mucinous cyst
• Pancreatic cancer
• Pancreatic cyst

• CEA
• EUS-FNA
• SPINK1
• cystic fluid glucose
• pancreatic cystic lesions

The commonly used magnetic resonance (MRI) criteria can be insufficient for discriminating mucinous from non-mucinous pancreatic cystic lesions (PCLs). The histological differences between PCLs’ fluid composition may be reflected in MRI images, but cannot be assessed by visual evaluation alone. We investigate whether additional MRI quantitative parameters such as signal intensity measurements (SIMs) and radiomics texture analysis (TA) can aid the differentiation between mucinous and non-mucinous PCLs. Fifty-nine PCLs (mucinous, n = 24; non-mucinous, n = 35) are retrospectively included. The SIMs were performed by two radiologists on T2 and diffusion-weighted images (T2WI and DWI) and apparent diffusion coefficient (ADC) maps. A total of 550 radiomic features were extracted from the T2WI and ADC maps of every lesion. The SIMs and TA features were compared between entities using univariate, receiver-operating, and multivariate analysis. The SIM analysis showed no statistically significant differences between the two groups (p = 0.69, 0.21–0.43, and 0.98 for T2, DWI, and ADC, respectively). Mucinous and non-mucinous PLCs were successfully discriminated by both T2-based (83.2–100% sensitivity and 69.3–96.2% specificity) and ADC-based (40–85% sensitivity and 60–96.67% specificity) radiomic features. SIMs cannot reliably discriminate between PCLs. Radiomics have the potential to augment the common MRI diagnosis of PLCs by providing quantitative and reproducible imaging features, but validation is required by further studies.

Although the probability of pancreatic cystic neoplasms (PCNs) being detected is raising year by year, their differential diagnosis and individualized treatment are still a challenge in clinical work. PCNs are tumors containing cystic components with different biological behaviors, and their clinical manifestations, epidemiology, imaging features, and malignant risks are different. Some are benign [e.g., serous cystic neoplasms (SCNs)], with a barely possible that turning into malignant, while others display a low or higher malignant risk [e.g., solid pseudopapillary neoplasms (SPNs), intraductal papillary mucinous neoplasms (IPMNs), and mucinous cystic neoplasms (MCNs)]. PCN management should concentrate on preventing the progression of malignant tumors while preventing complications caused by unnecessary surgical intervention. Clinically, various advanced imaging equipment are usually combined to obtain a more reliable preoperative diagnosis. The challenge for clinicians and radiologists is how to accurately diagnose PCNs before surgery so that corresponding surgical methods and follow-up strategies can be developed or not, as appropriate. The objective of this review is to sum up the clinical features, imaging findings and management of the most common PCNs according to the classic literature and latest guidelines.

• intraductal papillary mucinous neoplasms (IPMNs)
• mucinous cystic neoplasms (MCNs)
• pancreatic cystic neoplasms (PCNs)
• radiology
• serous cystic neoplasms (SCN)
• solid pseudopapillary neoplasms (SPN)

• inflammatory markers
• intraductal papillary mucinous neoplasm
• malignancy risk
• nomogram
• pancreatic cancer

• Carcinoma, Pancreatic Ductal/diagnosis
• Carcinoma, Pancreatic Ductal/pathology
• Carcinoma, Pancreatic Ductal/surgery
• Humans
• Neoplasm Invasiveness
• Nomograms
• Pancreas/pathology
• Pancreatic Neoplasms/diagnosis
• Pancreatic Neoplasms/pathology
• Pancreatic Neoplasms/surgery
• Retrospective Studies

• commentary
• incidental findings
• pancreas
• pancreatic cysts
• patient management

• Microscopy
• adverse effect
• confocal
• diagnosis
• endosonography
• pancreatic cyst

• Diffusion magnetic resonance imaging
• Magnetic resonance imaging
• Pancreatic cyst
• Pancreatic intraductal neoplasms

Cystic lesions of the pancreas may range from benign to precursors of pancreatic cancer. Simple mucinous cyst (SMC) is larger than 1 cm, has a gastric-type flat mucinous lining, and minimal atypia without ovarian-type stroma. We report a new case of pancreatic SMC, coupling a systematic review of the English literature mainly focused on their clinic-pathological features. We reviewed 103 cases of SMC in adults (73 women), averaging 57 (range, 26–70) years. The SMCs were located in the body-tail region of the pancreas in 60 (58%) cases, presenting as single cystic lesions in 94% of cases; 43% of patients were asymptomatic. A preoperative fine-needle aspiration of the cyst fluid detected amylase and carcinoembryonic antigen positivity in 71% and 76% of cases, respectively. Patients underwent surgery mostly for suspected malignancy; in 83% of cases, a standard pancreatic resection was performed. Mean SMC size was 4.9 (range, 1.5–12.0) cm. Mucins MUC5AC and MUC6 resulted positive in 77% and 81% of cases performed, respectively, whereas MUC2 was negative in all but one patient. The SMC from our institution was characterized by a KRAS somatic mutation. The diagnosis of SMC should be considered when a solitary pancreatic cyst larger than 1 cm is detected in asymptomatic patients. To establish a correct diagnosis, an extensive histologic/immunohistochemical analysis is essential. The presence of a KRAS mutation highlights that SMC may represent another potential pancreatic cancer precursor.

• Cystadenoma mucinous
• Pancreas
• Pancreatic cancer
• Pancreatic cyst

• Branch-duct intraductal papillary mucinous neoplasm
• Pancreas
• Pancreatic cancer
• Pancreatic cysts

• Adenocarcinoma, Mucinous
• Adult
• Aged
• Aged, 80 and over
• Carcinoma, Pancreatic Ductal/mortality
• Carcinoma, Pancreatic Ductal/pathology
• Clinical Decision-Making
• Female
• Follow-Up Studies
• Humans
• Incidence
• Male
• Middle Aged
• Pancreatectomy
• Pancreatic Cyst/epidemiology
• Pancreatic Cyst/pathology
• Pancreatic Ducts/pathology
• Pancreatic Neoplasms/mortality
• Pancreatic Neoplasms/pathology
• Retrospective Studies
• Treatment Outcome
• Young Adult

Background: Current efforts in the identification of new biomarkers are directed towards an accurate differentiation between benign and premalignant cysts. Thermal Liquid Biopsy (TLB) has been previously applied to inflammatory and tumor diseases and could offer an interesting point of view in this type of pathology. Methods: In this work, twenty patients (12 males and 8 females, average ages 62) diagnosed with a pancreatic cyst benign (10) and premalignant (10) cyst lesions were recruited, and biological samples were obtained during the endoscopic ultrasonography procedure. Results: Proteomic content of cyst liquid samples was studied and several common proteins in the different groups were identified. TLB cyst liquid profiles reflected protein content. Also, TLB serum score was able to discriminate between healthy and cysts patients (71% sensitivity and 98% specificity) and between benign and premalignant cysts (75% sensitivity and 67% specificity). Conclusions: TLB analysis of plasmatic serum sample, a quick, simple and non-invasive technique that can be easily implemented, reports valuable information on the observed pancreatic lesion. These preliminary results set the basis for a larger study to refine TLB serum score and move closer to the clinical application of TLB providing useful information to the gastroenterologist during patient diagnosis.

• diagnosis
• differential scanning calorimetry
• generalized linear models
• pancreatic cysts
• thermal liquid biopsy

• pancreatic cancer
• biomarkers
• early detection research network
• edrn
• surveillance
• early detection

• Aged
• Biomarkers, Tumor/metabolism
• Early Detection of Cancer/methods
• Female
• Humans
• Male
• Pancreatic Neoplasms/diagnosis
• Pancreatic Neoplasms

• U01 CA200468 NCI NIH HHS
• U01 CA200466 NCI NIH HHS
• P50 CA221707 NCI NIH HHS
• U01 CA152653 NCI NIH HHS
• R01 CA218004 NCI NIH HHS
• U01 CA226158 NCI NIH HHS
• U01 CA196403 NCI NIH HHS
• U01 CA210240 NCI NIH HHS
• U24 CA086368 NCI NIH HHS
• U01 CA086368 NCI NIH HHS

• fine-needle aspiration
• nondiagnostic
• pancreas
• root cause analysis

The prevalence of pancreatic cystic lesions (PCLs) has increased recently due to the increased use of cross-sectional abdominal imaging and the ageing global population. Current diagnostic techniques are inadequate to distinguish between PCLs that require surgery, close surveillance, or expectant management. This has resulted in increased morbidity from both inappropriately aggressive and conservative management strategies. Needle-based confocal laser endomicroscopy (nCLE) has allowed microscopic examination and visual delineation of the surface epithelium of PCLs. Landmark studies in this decade have correlated nCLE and histological findings and identified characteristics differentiating various types of PCLs. Subsequent studies have confirmed the high diagnostic yield of nCLE and its diagnostic utility in PCLs with an equivocal diagnosis. Moreover, nCLE has been shown to improve the diagnostic yield of PCLs. This will help avoid unnecessary pancreatic surgery, which carries significant morbidity and mortality risks. The early detection of high-grade dysplasia in PCLs will provide early surgical treatment and improve outcomes for pancreatic cancer. Despite the high upfront cost of nCLE, the improved diagnostic accuracy and resultant appropriate management have resulted in improved cost effectiveness. Refining the procedure technique and limiting the procedure length have significantly improved the safety of nCLE. A structured training program and device improvements to allow more complete mapping of the pancreatic cyst epithelium will be crucial for the widespread adoption of this promising technology.

• Cost effectiveness
• Endoscopic ultrasound
• Fine needle aspiration
• Needle-based confocal laser endomicroscopy
• Pancreatic cyst

Texture analysis of medical images has been reported to be a reliable method for differential diagnosis of neoplasms. This study was to investigate the performance of textural features and the combined performance of textural features and morphological characteristics in the differential diagnosis of pancreatic serous and mucinous cystadenomas.

We retrospectively reviewed 59 patients with pancreatic serous cystadenoma and 32 patients with pancreatic mucinous cystadenoma at our hospital. A three-dimensional region of interest (ROI) around the margin of the lesion was drawn manually in the CT images of each patient, and textural parameters were retrieved from the ROI. Textural features were extracted using the LifeX software. The least absolute shrinkage and selection operator (LASSO) method was applied to select the textural features. The differential diagnostic capabilities of morphological features, textural features, and their combination were evaluated using receiver operating characteristic (ROC) analysis, and the area under the receiver operating characteristic curve (AUC) was used as the main indicator. The diagnostic accuracy based on the AUC value is defined as follows: 0.9–1.0, excellent; 0.8–0.9, good; 0.7–0.8, moderate; 0.6–0.7, fair; 0.5–0.6, poor.

In the differential diagnosis of pancreatic serous and mucinous cystadenomas, the combination of morphological characteristics and textural features (AUC 0.893, 95% CI 0.816–0.970) is better than morphological characteristics (AUC 0.783, 95% CI 0.665–0.900) or textural features (AUC 0.777, 95% CI 0.673–0.880) alone.

In conclusion, our preliminary results highlighted the potential of CT texture analysis in discriminating pancreatic serous cystadenoma from mucinous cystadenoma. Furthermore, the combination of morphological characteristics and textural features can significantly improve the diagnostic performance, which may provide a reliable method for selecting patients with surgical intervention indications in consideration of the different treatment principles of the two diseases.

• Diagnosis
• Mucinous cystadenoma
• Multidetector computed tomography
• Pancreas
• Serous cystadenoma

• Serous cystic neoplasm
• malignancy
• risk
• surgical treatment

• Cyst diagnosis
• Cyst management
• Cyst treatment
• Mucinous cysts
• Pancreatic cysts

Mucinous nonneoplastic cyst of the pancreas is a rare disease defined as a cystic lesion lined with mucinous epithelium, supported by hypocellular stroma and not communicating with the pancreatic ducts. Mucinous nonneoplastic cyst of the pancreas has no malignant potential and does not require surgical resection or surveillance. However, its preoperative differentiation from other cystic lesions of the pancreas is difficult because of several overlapping clinical, radiological, and biochemical features. We report a rare case of large mucinous nonneoplastic cyst of the pancreas in which surgery was required due to infection and the possibility of malignancy.

A 75-year-old Japanese man was found to have a pancreatic cyst in 2006 while undergoing postoperative evaluation for colon cancer. In 2015, the cyst ruptured, and it was treated conservatively. In 2017, he fell down on a road with a fever of 40 °C and was transported emergently to a nearby hospital. Enhanced computed tomography revealed a cystic lesion in the body of the pancreas measuring 119 mm × 100 mm and an adjacent left renal cyst measuring 63 mm in diameter. The wall of the pancreatic cyst was thickened. Magnetic resonance imaging demonstrated a liquid surface in the pancreatic cyst. Pancreatic cyst infection was diagnosed as the source of infection. However, identification of the organism was difficult. Furthermore, due to the increase in the size and wall thickness of the cyst, it was unclear whether the cystic mass was neoplastic with malignant potential. For these reasons, the patient underwent distal pancreatectomy and splenectomy with deroofing of the left renal cyst. Intraoperatively, the pancreatic cyst adhered to the descending colon, and partial resection of the colon was added. Pathologic analysis of the resected cyst demonstrated a simple cyst lined by mucinous epithelium. There was no underlying stromal condensation or epithelial dysplasia, and communication with the native pancreatic ducts was not observed. Based on the operative and histological findings, a final diagnosis of mucinous nonneoplastic cyst of the pancreas with colonic communication was made. The colonic fistula was presumed to be the source of infection.

Mucinous nonneoplastic cyst of the pancreas is generally benign and requires little follow-up, but large cysts may penetrate other organs and cause severe complications.

• Colon fistula
• Infection
• Mucinous nonneoplastic cyst (MNNC)
• Pancreatic cyst

Widespread abdominal imaging has led to a substantial increase in the detection of incidentalomas. Currently, an increasing number of centers offer surveillance of the pancreas to individuals at high risk (IARs) of pancreatic ductal adenocarcinoma (PDAC).

The aims of this study were to evaluate the frequency and type of incidental findings in a magnetic resonance imaging (MRI)-based surveillance program for IARs for PDAC, and to discuss the benefit of detecting these lesions.

The outcome of MRI screening was reviewed in 568 individuals from three long-term pancreas surveillance programs conducted at three large European expert centers. All MRIs were studied in detail for the presence of incidental lesions.

The most common lesions were liver cysts, renal cysts and liver hemangioma, which together comprised 75% of all lesions. Only five (0.9%) patients underwent surgery for a benign lesion. Cancer was detected in 11 patients (1.9%); early detection of tumors was beneficial in at least five cases.

The present study demonstrates that extrapancreatic incidentaloma is a common finding in IARs for PDAC, but rarely requires additional treatment. CDKN2A-p16-Leiden mutation carriers were the only patient group found to harbor a substantial number of cancers, and detection resulted in benefit in several cases.

• High-risk individuals
• PDAC
• genetic predisposition
• incidental findings
• incidentaloma
• screening
• surveillance

Technological advances and the widespread use of medical imaging have led to an increase in the identification of pancreatic cysts in patients who undergo cross-sectional imaging. Current methods for the diagnosis and risk-stratification of pancreatic cysts are suboptimal, resulting in both unnecessary surgical resection and overlooked cases of neoplasia. Accurate diagnosis is crucial for guiding how a pancreatic cyst is managed, whether with surveillance for low-risk lesions or surgical resection for high-risk lesions. This review aims to summarize the current literature on confocal endomicroscopy and cyst fluid molecular analysis for the evaluation of pancreatic cysts. These recent technologies are promising adjuncts to existing approaches with the potential to improve diagnostic accuracy and ultimately patient outcomes.

• Pancreatic cysts
• Confocal endomicroscopy
• Molecular analysis
• Molecular biomarkers
• Pancreatic cancer

• Biomarkers/analysis
• Cyst Fluid/chemistry
• Diagnosis, Differential
• Endoscopy/methods
• Humans
• Intravital Microscopy/methods
• Microscopy, Confocal/methods
• Pancreas/diagnostic imaging
• Pancreas/pathology
• Pancreatic Cyst/diagnosis
• Pancreatic Cyst/pathology
• Pancreatic Neoplasms/diagnosis
• Pancreatic Neoplasms/pathology
• Watchful Waiting/methods

• Biomarker
• Pre-diagnostic
• Risk Stratification

• Animals
• Biomarkers, Tumor/analysis
• Biomarkers, Tumor/genetics
• Carcinoma, Pancreatic Ductal/diagnosis
• Carcinoma, Pancreatic Ductal/mortality
• Carcinoma, Pancreatic Ductal/therapy
• Diagnostic Imaging
• Early Detection of Cancer/methods
• Humans
• Incidence
• Molecular Imaging
• Pancreatic Neoplasms/diagnosis
• Pancreatic Neoplasms/mortality
• Pancreatic Neoplasms/therapy
• Precancerous Conditions/diagnosis
• Precancerous Conditions/mortality
• Precancerous Conditions/therapy
• Predictive Value of Tests
• Risk Assessment
• Risk Factors

• U01 CA200468 NCI NIH HHS
• P30 CA016672 NCI NIH HHS
• U01 DK108288 NIDDK NIH HHS
• P50 CA221707 NCI NIH HHS
• R01 CA218004 NCI NIH HHS
• U01 CA196403 NCI NIH HHS

• CT
• Serous pancreatic neoplasm
• growth rate
• pancreas
• serous cystadenoma
• serous cystic neoplasm

• Intraductal papillary mucinous neoplasm
• Pancreatic cancer
• Pancreatic ductal adenocarcinoma

• Carcinoma, Pancreatic Ductal/pathology
• Carcinoma, Pancreatic Ductal/surgery
• Clinical Decision-Making/methods
• Decision Support Techniques
• Disease Progression
• Humans
• Medical Oncology/standards
• Neoplasms, Second Primary/pathology
• Neoplasms, Second Primary/surgery
• Pancreatectomy/standards
• Pancreatic Intraductal Neoplasms/pathology
• Pancreatic Intraductal Neoplasms/surgery
• Practice Guidelines as Topic

To examine the practice pattern in Kaiser Permanente Southern California (KPSC), i.e., gastroenterology (GI)/surgery referrals and endoscopic ultrasound (EUS), for pancreatic cystic neoplasms (PCNs) after the region-wide dissemination of the PCN management algorithm.

Retrospective review was performed; patients with PCN diagnosis given between April 2012 and April 2015 (18 mo before and after the publication of the algorithm) in KPSC (integrated health system with 15 hospitals and 202 medical offices in Southern California) were identified.

2558 (1157 pre- and 1401 post-algorithm) received a new diagnosis of PCN in the study period. There was no difference in the mean cyst size (pre- 19.1 mm vs post- 18.5 mm, P = 0.119). A smaller percentage of PCNs resulted in EUS after the implementation of the algorithm (pre- 45.5% vs post- 34.8%, P < 0.001). A smaller proportion of patients were referred for GI (pre- 65.2% vs post- 53.3%, P < 0.001) and surgery consultations (pre- 24.8% vs post- 16%, P < 0.001) for PCN after the implementation. There was no significant change in operations for PCNs. Cost of diagnostic care was reduced after the implementation by 24%, 18%, and 36% for EUS, GI, and surgery consultations, respectively, with total cost saving of 24%.

In the current healthcare climate, there is increased need to optimize resource utilization. Dissemination of an algorithm for PCN management in an integrated health system resulted in fewer EUS and GI/surgery referrals, likely by aiding the physicians ordering imaging studies in the decision making for the management of PCNs. This translated to cost saving of 24%, 18%, and 36% for EUS, GI, and surgical consultations, respectively, with total diagnostic cost saving of 24%.

• Pancreatic cyst
• Algorithm incorporation
• Pancreas
• Optimization of resource utilization
• Fukuoka criteria
• Sendai criteria
• Pancreatic cancer
• Intraductal papillary mucinous neoplasm
• Practice management
• Algorithm

• Biomarker
• Prognostic Factor
• Surveillance
• Tumor

• Pancreaticoduodenectomy
• Whipple procedure
• pregnancy
• solid pseudopapillary neoplasm

• endosonography
• pancreatic cyst

• cancer/malignancy/neoplasia
• clinical decision-making
• clinical research/practice
• complication
• pancreas/simultaneous pancreas-kidney transplantation

Increases in the quality as well as utilization of cross-sectional imaging have led to rising diagnoses of pancreatic cystic lesions (PCL). Accurate presurgical diagnosis enables appropriate triage of PCLs. Unfortunately, current diagnostic approaches have suboptimal accuracy and may lead to unnecessary surgical resections or missed diagnoses of advanced neoplasia. Additionally, early detection represents an opportunity for intervention to prevent the progression to pancreatic adenocarcinoma. Our aim for this review is to systematically review the current literature on confocal endomicroscopy and molecular biomarkers in the evaluation of PCLs. Confocal laser endomicroscopy is a novel technology that allows for real-time in vivo microscopic imaging with multiple clinical trials identifying characteristic endomicroscopy findings of various pancreatic cystic lesions. DNA-based molecular markers have also emerged as another diagnostic modality as the pattern of genetic alternations present in cyst fluid can provide both diagnostic and prognostic data. We propose that both techniques can be utilized to improve patient outcomes.

• Pancreas
• Pancreatic cyst
• Pancreatic adenocarcinoma
• Confocal endomicroscopy
• Next generation sequencing
• Molecular marker

• 16S rRNA gene
• Bacterial translocation
• Cystic tumors
• Fusobacterium spp.
• Human Microbiome Project
• NGS
• Pancreatic cyst fluid

• Aged
• Bacteria/classification
• Bacteria/genetics
• Bacteria/isolation & purification
• Bacterial Translocation
• Bacteroides/genetics
• Bacteroides/isolation & purification
• DNA, Bacterial/genetics
• DNA, Bacterial/isolation & purification
• Female
• Fusobacterium/genetics
• Fusobacterium/isolation & purification
• Gastrointestinal Tract/microbiology
• High-Throughput Nucleotide Sequencing
• Humans
• Male
• Microbiota/genetics
• Middle Aged
• Neoplastic Processes
• Pancreas/microbiology
• Pancreas/physiopathology
• Pancreatic Cyst/microbiology
• Phylogeny
• Polymerase Chain Reaction
• RNA, Ribosomal, 16S/genetics
• Sequence Analysis, DNA
• Staphylococcus/genetics
• Staphylococcus/isolation & purification

• Endosonographic characteristics of pancreatic cysts
• Endosonographic-guided pancreas cyst ablation
• Fine needle aspiration
• Intraductal papillary mucinous neoplasm
• Mucinous cystic neoplasm
• Pancreatic cysts
• Serous cystic neoplasm

• Diagnostics
• Genetics
• Intraductal papillary mucinous neoplasm
• Mucinous cystic neoplasm
• Pancreas
• Pancreatic ductal adenocarcinoma
• Serous cystadenoma
• Solid-pseudopapillary neoplasm

• Endoscopic ultrasound
• Intraductal papillary mucinous neoplasm
• Mucinous cystic neoplasm
• Pancreatic cancer
• Pancreatic intraepithelial neoplasia