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For: Connolly SJ, Crowther M, Eikelboom JW, Gibson CM, Curnutte JT, Lawrence JH, Yue P, Bronson MD, Lu G, Conley PB, Verhamme P, Schmidt J, Middeldorp S, Cohen AT, Beyer-Westendorf J, Albaladejo P, Lopez-Sendon J, Demchuk AM, Pallin DJ, Concha M, Goodman S, Leeds J, Souza S, Siegal DM, Zotova E, Meeks B, Ahmad S, Nakamya J, Milling TJ. Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors. N Engl J Med 2019;380:1326-1335. [PMID: 30730782 PMCID: PMC6699827 DOI: 10.1056/nejmoa1814051] [Citation(s) in RCA: 643] [Impact Index Per Article: 107.2] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/18/2022]
Number Cited by Other Article(s)
1
Abdulla A, Donahue KR, Hall C, Culver LG, Morton C. Incidence of Venous Thromboembolism Post-Oral Anticoagulation Reversal in Intracranial Hemorrhage Patients. Ann Pharmacother 2025;59:501-510. [PMID: 39563016 DOI: 10.1177/10600280241297701] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/21/2024]  Open
2
Morello G, Alampi D, Aspide R, Beretta A, Bertuetti R, Bilotta F, Brogi E, Buscema G, Caricato A, Caruzzo D, Castioni CA, Chieregato A, Cortegiani A, De Cassai A, Fabbri A, Gelormini D, Gritti P, Guadrini L, Librizzi A, Latronico N, Limbucci N, Munari M, Picetti E, Pipitone G, Pucciarelli G, Robba C, Toni D, Sardo S, Zerbi SM, Zugni N, Rasulo F. Golden hour management in the patient with intraparenchymal cerebral hemorrhage: an Italian intersociety document. JOURNAL OF ANESTHESIA, ANALGESIA AND CRITICAL CARE 2025;5:25. [PMID: 40346657 PMCID: PMC12065239 DOI: 10.1186/s44158-025-00244-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Subscribe] [Scholar Register] [Received: 03/09/2025] [Accepted: 04/16/2025] [Indexed: 05/11/2025]
3
D’Abrantes S, Male C, Brown N, Bjursell M, Ambery P, Berggren A, Mattsson U. Anticoagulant prescribing trends, bleeding events, and reversal agent use in pediatric patients: A retrospective, real-world study. PLoS One 2025;20:e0323137. [PMID: 40338907 PMCID: PMC12061172 DOI: 10.1371/journal.pone.0323137] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/07/2023] [Accepted: 04/01/2025] [Indexed: 05/10/2025]  Open
4
Griffin M, Kwok CS, Qureshi AI, Lip GYH. The latest therapeutic advances with spontaneous intracerebral hemorrhage. Expert Rev Neurother 2025:1-13. [PMID: 40323128 DOI: 10.1080/14737175.2025.2502048] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/24/2025] [Accepted: 05/01/2025] [Indexed: 05/08/2025]
5
Selph L, Allison TA, Samuel S. Blood pressure management in the first 24 hours for intracerebral hemorrhage patients on oral anticoagulant therapy. Curr Med Res Opin 2025:1-8. [PMID: 40257438 DOI: 10.1080/03007995.2025.2495853] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/12/2024] [Revised: 04/15/2025] [Accepted: 04/16/2025] [Indexed: 04/22/2025]
6
Mishima Y, Townsend G, Clifton SC, Butt AL, Vandyck KB, Stewart KE, Boylan PM, Tanaka KA. Andexanet-induced heparin resistance in cardiac surgery-a rapid review of case reports and series. J Thromb Haemost 2025;23:1522-1530. [PMID: 39920998 DOI: 10.1016/j.jtha.2025.01.008] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/11/2024] [Revised: 12/16/2024] [Accepted: 01/27/2025] [Indexed: 02/10/2025]
7
Maegele M, Ntalouka M. Con: The Patient With Recent Intake of Direct Oral Anticoagulants-Problems Are Not Solved With the Approval of Reversal Agents. J Cardiothorac Vasc Anesth 2025;39:1348-1351. [PMID: 39952835 DOI: 10.1053/j.jvca.2025.01.031] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/13/2024] [Revised: 01/13/2025] [Accepted: 01/22/2025] [Indexed: 02/17/2025]
8
Arnaoutoglou E, Ntalouka MP. Pro: The Patient With the Recent Intake of DOACs Problems Are Solved With the Approval of Reversal Agents. J Cardiothorac Vasc Anesth 2025;39:1345-1347. [PMID: 39984366 DOI: 10.1053/j.jvca.2025.02.002] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/27/2024] [Revised: 01/20/2025] [Accepted: 02/02/2025] [Indexed: 02/23/2025]
9
Gikandi A, Connors JM, Nabzdyk CG, Zenati MA. Perioperative risks associated with administration of andexanet alfa during emergency cardiac surgery with circulatory arrest. Perfusion 2025;40:1045-1048. [PMID: 39052758 DOI: 10.1177/02676591241268395] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 07/27/2024]
10
Eikelboom JW, Sharma M, Xu L, Bamberg K, Beyer-Westendorf J, Falkenberg C, Ladenvall P, Narayan R, Penland RC, Verhamme P, Shoamanesh A. Association of Biomarkers With Intracerebral Hematoma Expansion and Arterial Thromboembolic Events in Patients With Acute Intracranial Hemorrhage: The ANNEXA-I Biomarker Substudy. Stroke 2025. [PMID: 40289797 DOI: 10.1161/strokeaha.124.049966] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2024] [Revised: 03/12/2025] [Accepted: 04/04/2025] [Indexed: 04/30/2025]
11
Martyak M, Soult A, Britt LD. Diagnosis and management of gastrointestinal hemorrhage: What you need to know. J Trauma Acute Care Surg 2025:01586154-990000000-00961. [PMID: 40205645 DOI: 10.1097/ta.0000000000004599] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/11/2025]
12
Crescioli G, Lombardi N, Arzenton E, Luxi N, Fumagalli S, Bonaiuti R, Cacini C, Mannaioni G, Trifirò G, Moretti U, Vannacci A. Safety of direct oral anticoagulants reversal agents in older patients: an analysis of individual case safety reports of adverse drug reaction from VigiBase®. Aging Clin Exp Res 2025;37:120. [PMID: 40192996 PMCID: PMC11976745 DOI: 10.1007/s40520-025-03025-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/27/2025] [Accepted: 03/23/2025] [Indexed: 04/10/2025]
13
Seiffge D, Polymeris A, Pfeilschifter W, Apostolaki-Hansson T, Ip B, Kristoffersen ES, Kuramatsu JB, Siepen BM. Reversal of anticoagulation in patients with intracerebral haemorrhage related to oral anticoagulants: State of the evidence. Eur Stroke J 2025;10:14-23. [PMID: 40401655 DOI: 10.1177/23969873241281477] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/23/2025]  Open
14
Sarhan K, Mohamed RG, Elmahdi RR, Mohsen Y, Elsayed A, Zayed DM, Elkholi MA, Gabr N, El-Bialy EM, Serag I. Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis. Neurocrit Care 2025;42:701-714. [PMID: 39379749 PMCID: PMC11950062 DOI: 10.1007/s12028-024-02130-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/12/2024] [Accepted: 09/06/2024] [Indexed: 10/10/2024]
15
Mehrara S, Patel R, DeRon N. Andexanet alfa for reversal of intracerebral haemorrhage resulting in ST-segment myocardial infarction: a case report. Eur Heart J Case Rep 2025;9:ytaf136. [PMID: 40201406 PMCID: PMC11975805 DOI: 10.1093/ehjcr/ytaf136] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/18/2024] [Revised: 01/16/2025] [Accepted: 03/19/2025] [Indexed: 04/10/2025]
16
Nagesh VK, Pulipaka SP, Bhuju R, Martinez E, Badam S, Nageswaran GA, Tran HHV, Elias D, Mansour C, Musalli J, Bhattarai S, Shobana LS, Sethi T, Sethi R, Nikum N, Trivedi C, Jarri A, Westman C, Ahmed N, Philip S, Weissman S, Weinberger J, Bangolo AI. Management of gastrointestinal bleed in the intensive care setting, an updated literature review. World J Crit Care Med 2025;14:101639. [DOI: 10.5492/wjccm.v14.i1.101639] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/21/2024] [Revised: 11/08/2024] [Accepted: 12/02/2024] [Indexed: 12/11/2024]  Open
17
Alhabeeb W, Tash A, Aljedai A, Morsy A, Khaliel F, Alhazmi I, AlSheef M, Arafah M, Alshammeri O, AlAhmari S. A Saudi Heart Association Position Statement on the use of DOACs in Patients With Arterial and Venous Thrombosis. J Saudi Heart Assoc 2025;37:2. [PMID: 40134412 PMCID: PMC11932698 DOI: 10.37616/2212-5043.1423] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/24/2024] [Revised: 02/07/2025] [Accepted: 02/11/2025] [Indexed: 03/27/2025]  Open
18
Salter B, Moffat K, Carlino S, Dobson-Storr J, Beckett L, Broomhead E, Onelöv L, Ge S, Atalla M, Melika R, Bansal S, Kitchen S, Crowther M, Mithoowani S. Evaluation of the MRX PT DOAC assay for detection of clinically relevant factor Xa inhibitor drug levels. J Thromb Haemost 2025;23:989-996. [PMID: 39675568 DOI: 10.1016/j.jtha.2024.12.005] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/30/2024] [Revised: 11/19/2024] [Accepted: 12/06/2024] [Indexed: 12/17/2024]
19
Bekka E, Liakoni E. Anticoagulation reversal (vitamin K, prothrombin complex concentrates, idarucizumab, andexanet-α, protamine). Br J Clin Pharmacol 2025;91:604-614. [PMID: 38926082 PMCID: PMC11862798 DOI: 10.1111/bcp.16142] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/01/2024] [Revised: 05/04/2024] [Accepted: 05/31/2024] [Indexed: 06/28/2024]  Open
20
Tallroth M, Östlundh L, Büki A, Cao Y, von Euler M, Ström JO. Reversal treatment and clinical outcomes in acute intracranial haemorrhage associated with oral anticoagulant use: protocol of a planned systematic review and meta-analysis. BMJ Open 2025;15:e090357. [PMID: 39965957 PMCID: PMC11836858 DOI: 10.1136/bmjopen-2024-090357] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 06/23/2024] [Accepted: 01/31/2025] [Indexed: 02/20/2025]  Open
21
Fujiwara G, Okada Y, Suehiro E, Yatsushige H, Hirota S, Hasegawa S, Karibe H, Miyata A, Kawakita K, Haji K, Aihara H, Yokobori S, Inaji M, Maeda T, Onuki T, Oshio K, Komoribayashi N, Suzuki M, Shiomi N. Development of Machine-learning Model to Predict Anticoagulant Use and Type in Geriatric Traumatic Brain Injury Using Coagulation Parameters. Neurol Med Chir (Tokyo) 2025;65:61-70. [PMID: 39721668 PMCID: PMC11891141 DOI: 10.2176/jns-nmc.2024-0066] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/15/2024] [Accepted: 10/03/2024] [Indexed: 12/28/2024]  Open
22
Iwasaki YK, Noda T, Akao M, Fujino T, Hirano T, Inoue K, Kusano K, Nagai T, Satomi K, Shinohara T, Soejima K, Sotomi Y, Suzuki S, Yamane T, Kamakura T, Kato H, Katsume A, Kondo Y, Kuroki K, Makimoto H, Murata H, Oka T, Tanaka N, Ueda N, Yamasaki H, Yamashita S, Yasuoka R, Yodogawa K, Aonuma K, Ikeda T, Minamino T, Mitamura H, Nogami A, Okumura K, Tada H, Kurita T, Shimizu W. JCS/JHRS 2024 Guideline Focused Update on Management of Cardiac Arrhythmias. Circ J 2025:CJ-24-0073. [PMID: 39956587 DOI: 10.1253/circj.cj-24-0073] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/18/2025]
23
Veltkamp R, Haas K, Rücker V, Malzahn U, Heeger A, Kinzler D, Müller P, Rappard P, Rizos T, Schiefer J, Opherk C, Pfeilschifter W, Althaus K, Schellinger P, Gaida B, Gabriel MM, Royl G, Nabavi DG, Haeusler KG, Nolte CH, Wolf ME, Poli S, Sieber M, Mosimann P, Heuschmann PU, Purrucker JC. Association of oral anticoagulants with risk of brain haemorrhage expansion compared to no-anticoagulation. Neurol Res Pract 2025;7:12. [PMID: 39934933 PMCID: PMC11921975 DOI: 10.1186/s42466-024-00358-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/06/2024] [Accepted: 11/10/2024] [Indexed: 02/13/2025]  Open
24
Diener HC, Kuklik N, Hüsing A, Alonso A, Nabavi DG, Poli S, Gabriel MM, Maier IL, Grans J. Andexanet alfa in patients with factor Xa inhibitor-associated intracranial hemorrhage: The prospective observational multicenter ASTRO-DE study. Int J Stroke 2025:17474930251317385. [PMID: 39834067 DOI: 10.1177/17474930251317385] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/22/2025]
25
Goldin M, Tsaftaridis N, Jnani J, Spyropoulos AC. Reversal of Direct Oral Anticoagulants (DOACs) for Critical Bleeding or Urgent Procedures. J Clin Med 2025;14:1013. [PMID: 39941682 PMCID: PMC11818480 DOI: 10.3390/jcm14031013] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/15/2024] [Revised: 01/23/2025] [Accepted: 02/03/2025] [Indexed: 02/16/2025]  Open
26
Leafloor C, Green R, Sharif S. Andexanet for factor Xa inhibitor-associated acute intracerebral hemorrhage. CAN J EMERG MED 2025;27:104-106. [PMID: 39760938 DOI: 10.1007/s43678-024-00845-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/28/2024] [Accepted: 11/21/2024] [Indexed: 01/07/2025]
27
Kopp SL, Vandermeulen E, McBane RD, Perlas A, Leffert L, Horlocker T. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (fifth edition). Reg Anesth Pain Med 2025:rapm-2024-105766. [PMID: 39880411 DOI: 10.1136/rapm-2024-105766] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/13/2024] [Accepted: 11/14/2024] [Indexed: 01/31/2025]
28
Qiu D, Wang L, Wang L, Dong Y. Human platelet lysate: a potential therapeutic for intracerebral hemorrhage. Front Neurosci 2025;18:1517601. [PMID: 39881806 PMCID: PMC11774881 DOI: 10.3389/fnins.2024.1517601] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/26/2024] [Accepted: 12/30/2024] [Indexed: 01/31/2025]  Open
29
Simioni P, Cipriano A, D'Angelo A, Giannasi G, Ricci G, Campello E, Susi B, Andreone V, Candelaresi P. The efficacy and safety of andexanet alfa in the treatment of anticoagulation-related major bleedings: An Italian perspective. Thromb Res 2025;245:109241. [PMID: 39700713 DOI: 10.1016/j.thromres.2024.109241] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/12/2024] [Revised: 12/04/2024] [Accepted: 12/08/2024] [Indexed: 12/21/2024]
30
Chabata CV, Yu H, Ke L, Frederiksen JW, Patel PA, Sullenger BA, Thalji NK. Andexanet Alfa-Associated Heparin Resistance in Cardiac Surgery: Mechanism and In Vitro Perspectives. Arterioscler Thromb Vasc Biol 2025;45:144-156. [PMID: 39569519 DOI: 10.1161/atvbaha.124.321650] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/07/2024] [Accepted: 11/04/2024] [Indexed: 11/22/2024]
31
Buka RJ. Andexanet alfa: trials just leave us with more questions. Res Pract Thromb Haemost 2025;9:102628. [PMID: 39868401 PMCID: PMC11760292 DOI: 10.1016/j.rpth.2024.102628] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/07/2024] [Revised: 10/27/2024] [Accepted: 11/04/2024] [Indexed: 01/28/2025]  Open
32
Frol S, Cortez GM, Pretnar-Oblak J, Ntaios G, Siddiqui AH, Levy EI. Letter: Use of Andexanet Alfa Before Urgent Neurosurgical and Neurointerventional Procedures: An Unresolved Issue. Neurosurgery 2025;96:e11-e13. [PMID: 39485026 DOI: 10.1227/neu.0000000000003254] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/09/2024] [Accepted: 09/13/2024] [Indexed: 11/03/2024]  Open
33
Mithoowani S, Bungard T, Castellucci L, Crowther M, de Wit K, Dowlatshahi D, Forbes N, Lin K, Siegal DM. Multidisciplinary Expert Guidance for the Management of Severe Bleeding on Oral Anticoagulation: An Algorithm for Practicing Clinicians. Thromb Haemost 2024. [PMID: 39515380 DOI: 10.1055/a-2464-2887] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/16/2024]
34
Mithoowani S, Siegal D. DOACs: role of anti-Xa and drug level monitoring. HEMATOLOGY. AMERICAN SOCIETY OF HEMATOLOGY. EDUCATION PROGRAM 2024;2024:178-185. [PMID: 39643984 DOI: 10.1182/hematology.2024000666] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 12/09/2024]
35
Seiffge DJ, Fandler-Höfler S, Du Y, Goeldlin MB, Jolink WMT, Klijn CJM, Werring DJ. Intracerebral haemorrhage - mechanisms, diagnosis and prospects for treatment and prevention. Nat Rev Neurol 2024;20:708-723. [PMID: 39548285 DOI: 10.1038/s41582-024-01035-w] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 10/11/2024] [Indexed: 11/17/2024]
36
Ageno W, Caramelli B, Donadini MP, Girardi L, Riva N. Changes in the landscape of anticoagulation: a focus on direct oral anticoagulants. Lancet Haematol 2024;11:e938-e950. [PMID: 39433055 DOI: 10.1016/s2352-3026(24)00281-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/07/2024] [Revised: 08/27/2024] [Accepted: 08/30/2024] [Indexed: 10/23/2024]
37
Dobesh PP, Coleman CI, Danese M, Lesén E, Chang RC, Odelade O, Fermann GJ. Management of factor Xa inhibitor-related traumatic non-intracranial bleeding events with andexanet alfa or four-factor prothrombin complex concentrate in a US multicenter observational study. J Am Coll Emerg Physicians Open 2024;5:e13333. [PMID: 39524040 PMCID: PMC11543631 DOI: 10.1002/emp2.13333] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/19/2024] [Revised: 09/18/2024] [Accepted: 09/27/2024] [Indexed: 11/16/2024]  Open
38
Sin CF, Wong KP, Siu CW, Wong TF, Wong HM. Utilization of international normalized ratio-derived formula to predict plasma rivaroxaban level-Validation study and real-world experience. Int J Lab Hematol 2024;46:1101-1108. [PMID: 39019497 DOI: 10.1111/ijlh.14347] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/01/2023] [Accepted: 06/27/2024] [Indexed: 07/19/2024]
39
Schönichen C, Sun S, Middelveld H, Huskens D, de Groot PG, Heemskerk JWM, Roest M, de Laat B. Functionally distinct anticoagulant mechanisms of endothelial cells. Thromb Res 2024;244:109208. [PMID: 39522336 DOI: 10.1016/j.thromres.2024.109208] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/30/2024] [Revised: 10/29/2024] [Accepted: 11/06/2024] [Indexed: 11/16/2024]
40
Røed-Undlien H, Schultz NH, Husebråten IM, Wollmann BM, Akerkar RR, Molden E, Amundsen EK, Bjørnstad JL. Apixaban removal during emergency surgery for type A acute aortic dissection: a prospective cohort study. Int J Surg 2024;110:7782-7790. [PMID: 39806740 PMCID: PMC11634093 DOI: 10.1097/js9.0000000000002137] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/21/2024] [Accepted: 11/05/2024] [Indexed: 01/16/2025]
41
Rodrigues A, Gonçalves LR, Gregório T, Baldaia C, Santo GC, Gouveia J. Urgent Reversal of Direct Oral Anticoagulants in Critical and Life-Threatening Bleeding: A Multidisciplinary Expert Consensus. J Clin Med 2024;13:6842. [PMID: 39597986 PMCID: PMC11595216 DOI: 10.3390/jcm13226842] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/18/2024] [Revised: 11/08/2024] [Accepted: 11/11/2024] [Indexed: 11/29/2024]  Open
42
Wienhold J, Rossaint R, Vandeput E, Grottke O. The Efficacy of Andexanet Alfa for the Reversal of Factor Xa Inhibitors Is Not Influenced by Hemodilution with Different Volume Expanders. J Clin Med 2024;13:6706. [PMID: 39597850 PMCID: PMC11594903 DOI: 10.3390/jcm13226706] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/09/2024] [Revised: 10/29/2024] [Accepted: 11/02/2024] [Indexed: 11/29/2024]  Open
43
Gigante B, Tamargo J, Agewall S, Atar D, Ten Berg J, Campo G, Cerbai E, Christersson C, Dobrev D, Ferdinandy P, Geisler T, Gorog DA, Grove EL, Kaski JC, Rubboli A, Wassmann S, Wallen H, Rocca B. Update on antithrombotic therapy and body mass: a clinical consensus statement of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy and the European Society of Cardiology Working Group on Thrombosis. EUROPEAN HEART JOURNAL. CARDIOVASCULAR PHARMACOTHERAPY 2024;10:614-645. [PMID: 39237457 DOI: 10.1093/ehjcvp/pvae064] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 07/24/2024] [Revised: 08/16/2024] [Indexed: 09/07/2024]
44
Mair A, Sahli SD, Studt JD, Braun J, Lunkiewicz J, Spahn DR, Kaserer A. Impact of elevated direct factor Xa inhibitor plasma levels on perioperative blood loss in patients undergoing urgent surgery. Transfusion 2024;64:2114-2123. [PMID: 39319425 DOI: 10.1111/trf.18021] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/28/2024] [Revised: 09/06/2024] [Accepted: 09/07/2024] [Indexed: 09/26/2024]
45
Wilson SJ, Gelovani D, Von A, Kaatz S, Grant PJ. Medical Clinics of North America-Periprocedural Antithrombotics: Prophylaxis and Interruption. Med Clin North Am 2024;108:1017-1037. [PMID: 39341611 DOI: 10.1016/j.mcna.2024.04.005] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/01/2024]
46
Hou H, Qu Z, Liu R, Jiang B, Wang L, Li A. Traumatic brain injury: Advances in coagulopathy (Review). Biomed Rep 2024;21:156. [PMID: 39268405 PMCID: PMC11391523 DOI: 10.3892/br.2024.1844] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/26/2024] [Accepted: 08/05/2024] [Indexed: 09/15/2024]  Open
47
von Heymann C, Afshari A, Ahmed A, Arnaoutoglou E, Bolliger D, Fenger-Eriksen C, Grottke O. Commentary on the ANNEXA-I trial from the guideline group of the European Society of Anaesthesiology and Intensive Care (ESAIC) on the reversal of direct oral anticoagulants in patients with life threatening bleeding. Eur J Anaesthesiol 2024;41:867-868. [PMID: 39514740 DOI: 10.1097/eja.0000000000002061] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/16/2024]
48
Roman C, Mihaila R, Cindea CN, Iliescu A, Roman-Filip I, Stingaciu AR, Breazu A, Saceleanu V. Anticoagulation Reversal in Intracerebral Hemorrhage: A Case Report on the Efficacy of Andexanet Alfa in an Apixaban-Treated Patient. Cureus 2024;16:e74750. [PMID: 39734980 PMCID: PMC11682709 DOI: 10.7759/cureus.74750] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 11/29/2024] [Indexed: 12/31/2024]  Open
49
Shaw JR, Almujalli AA, Xu Y, Levy JH, Schulman S, Siegal D, Dowlatshahi D, Tokessy M, Buyukdere H, Carrier M, Castellucci LA. Prothrombin complex concentrate for direct factor Xa inhibitor-associated bleeding or before urgent surgery. Thromb Res 2024;243:109172. [PMID: 39362177 DOI: 10.1016/j.thromres.2024.109172] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/17/2024] [Revised: 09/20/2024] [Accepted: 09/23/2024] [Indexed: 10/05/2024]
50
Levy JH, Shaw JR, Castellucci LA, Connors JM, Douketis J, Lindhoff-Last E, Rocca B, Samama CM, Siegal D, Weitz JI. Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH. J Thromb Haemost 2024;22:2889-2899. [PMID: 39029742 DOI: 10.1016/j.jtha.2024.07.009] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/15/2024] [Revised: 07/04/2024] [Accepted: 07/08/2024] [Indexed: 07/21/2024]
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