Regulation of hepatic microRNA expression by hepatocyte nuclear factor 4 alpha

doi:10.4254/wjh.v9.i4.191

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Feb 8, 2017; 9(4): 191-208
Published online Feb 8, 2017. doi: 10.4254/wjh.v9.i4.191

Table 1 Targeting of human and mouse genes by liver-predominant microRNAs predicted by TargetScan

	Predicted pairing of target region (top) and microRNA (bottom)	Seed match	Context score percentile
Position 1085-1091 of human H3F3B 3’UTR	5’ ...AUUUACUGAAGUUUUUAGGUCAA...	8 mer	96
miR-192/215	\|\|\|\|\|\|\|
	3’ CCGACAGUUAAGUAUCCAGUC
Position 1064-1070 of mouse H3f3b 3’UTR	5’ ...UCCUAUUGAAGUUUUUAGGUCAA...	8 mer	99
miR-192/215	\|\|\|\|\|\|\|
	3’ CCGACAGUUAAGUAUCCAGUC
Position 1109-1115 of human CHD1 3’UTR	5’ ...GACUUUUAAUAUAAACUGUUACA...	8 mer	99
miR-194	\|\|\|\|\|\|\|
	3’ AGGUGUACCUCAACGACAAUGU
Position 1100-1106 of mouse Chd1 3’UTR	5’ ...GCUUUAAUAUAAAAACUGUUACA...	8 mer	99
miR-194	\|\|\|\|\|\|\|
	3’ AGGUGUACCUCAACGACAAUGU

3’UTR: Untranslated regions.

Citation: Lu H, Lei X, Liu J, Klaassen C. Regulation of hepatic microRNA expression by hepatocyte nuclear factor 4 alpha. World J Hepatol 2017; 9(4): 191-208
URL: https://www.wjgnet.com/1948-5182/full/v9/i4/191.htm
DOI: https://dx.doi.org/10.4254/wjh.v9.i4.191