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©The Author(s) 2017.
World J Hepatol. Sep 28, 2017; 9(27): 1125-1132
Published online Sep 28, 2017. doi: 10.4254/wjh.v9.i27.1125
Published online Sep 28, 2017. doi: 10.4254/wjh.v9.i27.1125
Table 1 Baseline characteristics of the 87 patients at enrollment
Characteristic | |
Age (yr) | 58.1 ± 7.6 |
Male | 68 (78.2) |
Etiology of cirrhosis | |
Alcohol | 71 (81.6) |
Viruses | 12 (13.8) |
NASH | 7 (8.0) |
Others | 2 (2.3) |
TIPS indication | |
Recurrent bleeding | 30 (34.5) |
Refractory ascites | 59 (67.8) |
Hydrothorax | 4 (4.6) |
Child-Pugh score, n = 86 | 7.8 ± 1.6 |
Child-Pugh score, n = 86 | |
A | 18 (20.9) |
B | 58 (67.4) |
C | 10 (11.6) |
MELD score | 11.6 ± 3.4 |
Table 2 Suspicion of dysfunction based on the conclusion of the operator, according to the localization of the stenosis n (%)
Dysfunction suspected (n = 21 stenosis) | Not suspected (n = 18 stenosis) | |
Lower part of the stent | 6 (28.6) | 2 (11.1) |
Middle part of the stent | 4 (19.1) | 4 (22.2) |
Upper part of the stent | 8 (38.1) | 8 (44.4) |
Hepatic vein | 3 (14.3) | 4 (22.2) |
Table 3 Performance of Doppler-ultrasonography binary criteria for the diagnosis of transjugular intrahepatic portosystemic shunt dysfunction
Variables | n paired | n patients | Sensitivity (95%CI) | Specificity (95%CI) | PPV | NPV (95%CI) |
Portal flow modulation | 177 | 73 | 44.4 (31.2-57.6) | 79.6 (67.3-91.4) | 56.4 (37.8-76.3) | 71.1 (62.6-78.8) |
Direction in right branch | 173 | 76 | 57.2 (44.6-70.1) | 61.7 (48.9-73.1) | 45.2 (33.7-58.3) | 72.4 (62.6-80.5) |
Direction in left branch | 171 | 77 | 54.7 (39.6-69.7) | 66.8 (54.4-78.1) | 48.5 (34.8-63.8) | 72.1 (61.3-82.3) |
Stent filling | 140 | 64 | 31.3 (18.8-44.2) | 81.8 (72.4-89.8) | 54.1 (36.0-71.0) | 63.4 (52.2-73.6) |
Ascites | 218 | 87 | 27.9 (16.9-39.7) | 90.6 (84.0-95.4) | 62.9 (43.7-79.1) | 68.7 (61.0-76.1) |
Conclusion | 218 | 87 | 39.1 (27.6-51.4) | 87.1 (79.3-93.3) | 63.5 (45.8-79.8) | 71.5 (63.6-78.5) |
Table 4 Performance of Doppler-ultrasonography quantitative criteria for the diagnosis of transjugular intrahepatic portosystemic shunt dysfunction
Patients | Paired procedures | AUC | 95%CI | |
Portal velocity | 80 | 192 | 0.655 | 0.553-0.749 |
Stent velocity | 80 | 195 | 0.536 | 0.454-0.634 |
Portal velocity delta | 63 | 150 | 0.577 | 0.485-0.679 |
Delta + right direction | 58 | 128 | 0.626 | 0.530-0.726 |
- Citation: Nicolas C, Le Gouge A, d’Alteroche L, Ayoub J, Georgescu M, Vidal V, Castaing D, Cercueil JP, Chevallier P, Roumy J, Trillaud H, Boyer L, Le Pennec V, Perret C, Giraudeau B, Perarnau JM, STIC-TIPS group. Evaluation of Doppler-ultrasonography in the diagnosis of transjugular intrahepatic portosystemic shunt dysfunction: A prospective study. World J Hepatol 2017; 9(27): 1125-1132
- URL: https://www.wjgnet.com/1948-5182/full/v9/i27/1125.htm
- DOI: https://dx.doi.org/10.4254/wjh.v9.i27.1125