Prevalence of significant liver disease in human immunodeficiency virus-infected patients exposed to Didanosine: A cross sectional study

Table 1 Characteristics of those with liver disease identified as a result of study screening

Subject number	Gender	Age (yr)	Ethnicity	Prior DDI exposure (mo)	Time since DDI (yr)	BMI (kg/m2)	MAST score	ALT (IU/mL)	PLTs (106/L)	PTT	Alk Phos (U/L)	FS (kPa)	Ultrasound results	Biopsy results	HVPG	Fib 4
Participants who accepted to undergo TJLB as a result of study screening
1	Male	43	White British	81	7	25.58	0	77	175	14.0	83	10	Splenomegaly	NRH with mild steatosis	5	1.29
2	Male	59	White British	40	6	24.42	0	36	175	14.8	93	8	Normal	NRH	4	2.39
3	Male	48	White British	9	6	29.76	0	32	184	14.3	108	NR	Fatty liver, Splenomegaly	Moderate steatosis	3	1.08
4	Male	52	White British	70	7	24.69	0	50	242	11.7	44	5.6	Fatty liver	Mild steatosis	3	0.79
5	Male	49	White Other	34	4	28.54	1	60	215	14.0	83	12.6	Fatty liver	Moderate steatosis, moderate fibrosis	3	1.38
6	Male	52	White British	21	11	28.67	1	58	257	13.4	43	NR	Fatty liver	Moderate steatosis	Not done	1.02
7	Male	62	White Other	13	13	32.56	2	56	175	11.1	45	NR	Fatty liver	Moderate steatosis	2	2.25
8	Male	50	White British	117	3	31.18	0	125	204	10.7	58	8.7	Fatty liver	Mild fibrosis with mild steatosis	2	1.71
9	Female	56	Black African	24	11	36.96	0	27	208	12.3	67	4.4	Coarse echotexture	Normal Architecture	5	1.07
10	Male	57	White British	61	4		0	40	190	13.9	71	NR	Splenomegaly	Normal Architecture	3	1.74
11	Male	51	White Irish	103	4	20.30	0	56	228	10.8	154	4.8	Coarse echotexture	Normal Architecture	3	1.04
12	Male	52	White Other	44	5	21.07	6	24	224	11.4	62	9.1	Normal	Normal Architecture	2	1.16
Participants who refused TJLB offered as a result of study screening
13	Male	46	White British	74	2	21.46	0	18	177		60	10	Normal	Declined		1.41
14	Male	41	White British	97	3	25.65	0	63	188		101	7.6	Splenomegaly	Declined		1.30
15	Male	47	White British	33	5	24.39	0	34	238		58	7.1	Fatty liver, dampened waveform	Declined		0.99
16	Male	61	White British	110	2	20.75	1	35	246		71	9.2	Normal	Declined		1.39
17	Male	54	White British	28	5	28.93	1	32	333		58	4.3	Fatty liver	Declined		0.67

DDI: Didanosine; BMI: Body mass index; MAST: Michigan Alcoholism Screening test; ALT: Alanine transaminase; PLT: Platelet count; FS: FibroScan; TJLB: Trans-jugular liver biopsy.