Peres NP, Galbiatti-Dias ALS, Castanhole-Nunes MMU, da Silva RF, Pavarino ÉC, Goloni-Bertollo EM, Ruiz-Cintra MT. Polymorphisms of folate metabolism genes in patients with cirrhosis and hepatocellular carcinoma. World J Hepatol 2016; 8(29): 1234-1243 [PMID: 27803768 DOI: 10.4254/wjh.v8.i29.1234]
Corresponding Author of This Article
Eny Maria Goloni-Bertollo, MD, São José do Rio Preto Medical School, FAMERP and Medical School Fundation, FUNFARME, Av. Brigadeiro Faria Lima, 5416, São José do Rio Preto 15090-000, Brazil. eny.goloni@famerp.br
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Control Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 2 Association of MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G polymorphisms with hepatocellular carcinoma, adjusted for gender, age, smoking and alcohol consumption
Table 3 Association of MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G polymorphisms with Liver Cirrhosis, adjusted for gender, age, smoking and alcohol consumption
Table 4 Interaction between MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G polymorphisms and smoking habits or alcohol drinking on the risk of hepatocellular carcinoma
Table 5 Interaction between MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G polymorphisms and smoking habits or alcohol drinking on the risk of liver cirrhosis
Table 6 Regression analysis of data from multiple logistic analyzed clinical parameters and polymorphisms in patients with hepatocellular carcinoma tumors divided into stages 0 and tumore in stages A and B, C and D according barcelona clinic liver cancer criteria
Citation: Peres NP, Galbiatti-Dias ALS, Castanhole-Nunes MMU, da Silva RF, Pavarino ÉC, Goloni-Bertollo EM, Ruiz-Cintra MT. Polymorphisms of folate metabolism genes in patients with cirrhosis and hepatocellular carcinoma. World J Hepatol 2016; 8(29): 1234-1243