Copyright
©The Author(s) 2016.
World J Hepatol. May 28, 2016; 8(15): 637-643
Published online May 28, 2016. doi: 10.4254/wjh.v8.i15.637
Published online May 28, 2016. doi: 10.4254/wjh.v8.i15.637
Characteristic | Treatment group | Control group | P-value |
No. | 20 | 40 | |
Mean age at entry in year ± SD | 33.80 ± 11.45 | 33.85 ± 8.37 | 0.985 |
Age > 40 yr, n (%) | 4 (20.0) | 11 (27.5) | 0.527 |
Men:women, n | 15:5 | 30:10 | 1.000 |
Mean baseline ALT (U/L) ± SD | 23.46 ± 8.78 | 21.24 ± 10.26 | 0.874 |
HBsAg level (IU/mL) | |||
Mean ± SD | 26.22 ± 33.00 | 25.72 ± 5.58 | 0.949 |
Median (Q1, Q3) | 11.36 (3.52-37.40) | 15.81 (4.59-40.15) | 0.714 |
95%CI of patients with 10-100 IU/mL, n (%) | (10.77, 41.75), 10 (50.0) | (17.54, 33.90), 22 (55.0) | |
Patients with < 10 IU/mL, n (%) | 10 (50.0) | 18 (45.0) | |
Mean decline in HBsAg level at EOT (IU/mL) ± SD | 22.33 ± 29.45 | 5.76 ± 17.67 | 0.009 |
Median HBsAg level at EOT (IU/mL) | 0.04 (0.02, 0.55) | 13.21 (2.97, 30.31) | 0.003 |
(Q1, Q3) | 95%CI: (-0.68, 8.53) | 95%CI: (12.8, 27.12) | |
Mean decline in HBsAg level at EOF (IU/mL) ± SD | 23.36 ± 29.47 | 8.61 ± 19.32 | 0.023 |
Median HBsAg level at EOF (IU/mL) | 0.045 (0.02, 2.44) | 5.69 (1.50, 20.88) | 0.007 |
(Q1, Q3) | 95%CI: (-1.63, 7.43) | 95%CI: (10.20, 24.03) | |
HBsAg loss, n (%) | 13 (65.0) | 0 (0) | 0.000 |
HBsAg seroconversion, n (%) | 12 (60.0) | 0 (0) | 0.000 |
HBV DNA reactivation, n (%) | 0 (0) | 2 (5.0) | 0.309 |
- Citation: Li MH, Xie Y, Zhang L, Lu Y, Shen G, Wu SL, Chang M, Mu CQ, Hu LP, Hua WH, Song SJ, Zhang SF, Cheng J, Xu DZ. Hepatitis B surface antigen clearance in inactive hepatitis B surface antigen carriers treated with peginterferon alfa-2a. World J Hepatol 2016; 8(15): 637-643
- URL: https://www.wjgnet.com/1948-5182/full/v8/i15/637.htm
- DOI: https://dx.doi.org/10.4254/wjh.v8.i15.637