Vertical hepatitis C virus transmission: Main questions and answers

doi:10.4254/wjh.v6.i8.538

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Aug 27, 2014 (publication date) through Nov 15, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Aug 27, 2014; 6(8): 538-548
Published online Aug 27, 2014. doi: 10.4254/wjh.v6.i8.538

Table 1 Clinical factors and risk of vertical transmission

Associated with vertical transmission

Pregnant woman: High HCV viral load

Elevated ALT levels before pregnancy

HIV-HCV co-infection iv drug abuse¹

Obstetric procedures:

Prolonged rupture of membranes vaginal and/or perineal lacerations invasive monitoring of fetus intrauterine pressure catheter amniocentesis (debated)

Father HCV infection¹

Fetus gender¹

Not associated with vertical transmission

Maternal HCV genotype

Mode of delivery²

Breastfeeding²

¹To be confirmed;

²Except in the presence of HIV-HCV coinfection. HCV: Hepatitis C virus; HIV: Human immunodeficiency virus.

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Citation: Tosone G, Maraolo AE, Mascolo S, Palmiero G, Tambaro O, Orlando R. Vertical hepatitis C virus transmission: Main questions and answers. World J Hepatol 2014; 6(8): 538-548
URL: https://www.wjgnet.com/1948-5182/full/v6/i8/538.htm
DOI: https://dx.doi.org/10.4254/wjh.v6.i8.538