Obesity and non-alcoholic fatty liver disease: Disparate associations among Asian populations

Table 1 Increased odds of hypertension and diabetes associated with one unit increase in body mass index

	Hypertension			Diabetes
	OR	95%CI	P value	OR	95%CI	P value
Asian	1.15	1.13-1.18	< 0.001	1.15	1.13-1.18	< 0.001
Non-Hispanic White	1.11	1.10-1.11	< 0.001	1.11	1.11-1.12	< 0.001
Black	1.08	1.07-1.10	< 0.001	1.07	1.06-1.09	< 0.001
Hispanic	1.08	1.07-1.09	< 0.001	1.08	1.07-1.09	< 0.001

Table 2 Etiology of liver disease among liver transplantation recipients in the United States, 1992-2012, United Network for Organ Sharing database n (%)

Liver disease etiology	Pre-MELD (1992-2002)	Post-MELD (2003-2007)	Post-MELD (2008-2012)
Acute liver failure	2390 (7.9)	1639 (6.9)	1285 (5.1)
Chronic HCV	9248 (30.7)	7970 (33.5)	7803 (31.2)
Chronic HBV	1419 (4.7)	802 (3.4)	604 (2.4)
HCC	466 (1.6)	1714 (7.2)	3423 (13.7)
ALD	5027 (16.7)	3704 (15.6)	3636 (14.6)
ALD + HCV	2495 (8.3)	1845 (7.8)	1529 (6.1)
NASH	8 (0.1)	796 (3.3)	2162 (8.7)
AIH	1277 (4.2)	715 (3.0)	693 (2.8)
Cryptogenic	3460 (11.5)	2115 (8.9)	1634 (6.5)
PBC	1992 (6.6)	1009 (4.2)	795 (3.2)
PSC	1648 (5.5)	1 (4.3)	922 (3.7)
Metabolic	729 (2.4)	478 (2.0)	491 (2.0)

Metabolic includes Wilson disease, alpha-1 antitrypsin disease and hemochromatosis. MELD: Model for end stage liver disease; HCV: Hepatitis C virus; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; ALD: Alcoholic liver disease; NASH: Non-alcoholic steatohepatitis; AIH: Autoimmune hepatitis; PBC: Primary biliary cirrhosis; PSC: Primary sclerosing cholangitis.